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Literature summary extracted from

  • Jurkowska, H.; Placha, W.; Nagahara, N.; Wrobel, M.
    The expression and activity of cystathionine-gamma-lyase and 3-mercaptopyruvate sulfurtransferase in human neoplastic cell lines (2011), Amino Acids, 41, 151-158.
    View publication on PubMed

Natural Substrates/ Products (Substrates)

EC Number Natural Substrates Organism Comment (Nat. Sub.) Natural Products Comment (Nat. Pro.) Rev. Reac.
2.8.1.2 3-mercaptopyruvate + cyanide Homo sapiens
-
 pyruvate + thiocyanate
-
 ?

Organism

EC Number Organism UniProt Comment Textmining
2.8.1.2 Homo sapiens
-
-
-
4.4.1.1 Homo sapiens
-
-
-

Source Tissue

EC Number Source Tissue Comment Organism Textmining
2.8.1.2 A-375 cell
-
 Homo sapiens
-
2.8.1.2 astrocytoma cell
-
 Homo sapiens
-
2.8.1.2 melanoma cell
-
 Homo sapiens
-
2.8.1.2 neuroblastoma cell
-
 Homo sapiens
-
2.8.1.2 SH-SY5Y cell highest expression Homo sapiens
-
2.8.1.2 U-373MG cell
-
 Homo sapiens
-
2.8.1.2 WM-35 cell
-
 Homo sapiens
-
4.4.1.1 A-375 cell expression of both cystathionine gamma-lyase and 3-mercaptopyruvate sulfurtransferase, the activity of 3-mercaptopyruvate sulfurtransferase is higher than that of cystathionine gamma-lyase Homo sapiens
-
4.4.1.1 SH-SY5Y cell expression of both cystathionine gamma-lyase and 3-mercaptopyruvate sulfurtransferase, the activity of 3-mercaptopyruvate sulfurtransferase is higher than that of cystathionine gamma-lyase. The low level of cystathionine gamma-lyase and low GSH/GSSG ratio correspond with the highest cystathionine gamma-lyase activity mong the cell lines tested Homo sapiens
-
4.4.1.1 U-373MG cell expression of both cystathionine gamma-lyase and 3-mercaptopyruvate sulfurtransferase, the activity of 3-mercaptopyruvate sulfurtransferase is higher than that of cystathionine gamma-lyase. Very low activity of cystathionine gamma-lyase Homo sapiens
-
4.4.1.1 WM-35 cell expression of both cystathionine gamma-lyase and 3-mercaptopyruvate sulfurtransferase, the activity of 3-mercaptopyruvate sulfurtransferase is higher than that of cystathionine gamma-lyase Homo sapiens
-

Substrates and Products (Substrate)

EC Number Substrates Comment Substrates Organism Products Comment (Products) Rev. Reac.
2.8.1.2 3-mercaptopyruvate + cyanide
-
 Homo sapiens pyruvate + thiocyanate
-
 ?

Synonyms

EC Number Synonyms Comment Organism
2.8.1.2 MPST
-
 Homo sapiens