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Literature summary extracted from

  • Sale, C.; Saunders, B.; Harris, R.
    Effect of beta-alanine supplementation on muscle carnosine concentrations and exercise performance (2010), Amino Acids, 39, 321-333.
    View publication on PubMed

Natural Substrates/ Products (Substrates)

EC Number Natural Substrates Organism Comment (Nat. Sub.) Natural Products Comment (Nat. Pro.) Rev. Reac.
6.3.2.11 ATP + L-His + beta-Ala Homo sapiens the concentration of histidine in muscle and plasma is high relative to its Km with muscle carnosine synthase, whereas beta-alanine exists in low concentration in muscle and has a higher Km with muscle carnosine synthase, which indicates that it is the availability of beta-alanine that is limiting to the synthesis of carnosine in skeletal muscle ADP + phosphate + carnosine
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Organism

EC Number Organism UniProt Comment Textmining
6.3.2.11 Homo sapiens
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-
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Substrates and Products (Substrate)

EC Number Substrates Comment Substrates Organism Products Comment (Products) Rev. Reac.
6.3.2.11 ATP + L-His + beta-Ala the concentration of histidine in muscle and plasma is high relative to its Km with muscle carnosine synthase, whereas beta-alanine exists in low concentration in muscle and has a higher Km with muscle carnosine synthase, which indicates that it is the availability of beta-alanine that is limiting to the synthesis of carnosine in skeletal muscle Homo sapiens ADP + phosphate + carnosine
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?

Synonyms

EC Number Synonyms Comment Organism
6.3.2.11 carnosine synthase
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Homo sapiens