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Literature summary extracted from

  • Tachibana, T.; Kato, M.; Watanabe, T.; Mitsui, T.; Sugiyama, Y.
    Method for predicting the risk of drug-drug interactions involving inhibition of intestinal CYP3A4 and P-glycoprotein (2009), Xenobiotica, 39, 430-443.
    View publication on PubMed

Application

EC Number Application Comment Organism
7.6.2.2 medicine development of a method for predicting the risk of drug-drug interactions involving inhibition of P-glycoprotein Homo sapiens

Organism

EC Number Organism UniProt Comment Textmining
7.6.2.2 Homo sapiens
-
-
-

Substrates and Products (Substrate)

EC Number Substrates Comment Substrates Organism Products Comment (Products) Rev. Reac.
7.6.2.2 ATP + H2O + digoxin/in
-
 Homo sapiens ADP + phosphate + digoxin/out
-
 ?
7.6.2.2 ATP + H2O + fexofenadine/in
-
 Homo sapiens ADP + phosphate + fexofenadine/out
-
 ?
7.6.2.2 ATP + H2O + talinolol/in
-
 Homo sapiens ADP + phosphate + talinolol/out
-
 ?

Synonyms

EC Number Synonyms Comment Organism
7.6.2.2 P-glycoprotein
-
 Homo sapiens