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Literature summary extracted from

  • Kobayashi, T.; Wada, H.; Usui, M.; Sakurai, H.; Matsumoto, T.; Nobori, T.; Katayama, N.; Uemoto, S.; Ishizashi, H.; Matsumoto, M.; Fujimura, Y.; Isaji, S.
    Decreased ADAMTS13 levels in patients after living donor liver transplantation (2009), Thromb. Res., 124, 541-545.
    View publication on PubMed

Localization

EC Number Localization Comment Organism GeneOntology No. Textmining
3.4.24.87 extracellular secrete enzyme Homo sapiens
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Natural Substrates/ Products (Substrates)

EC Number Natural Substrates Organism Comment (Nat. Sub.) Natural Products Comment (Nat. Pro.) Rev. Reac.
3.4.24.87 von Willebrand factor + H2O Homo sapiens
-
 ?
-
 ?

Organism

EC Number Organism UniProt Comment Textmining
3.4.24.87 Homo sapiens
-
-
-

Source Tissue

EC Number Source Tissue Comment Organism Textmining
3.4.24.87 hepatocyte ADAMTS13 and von Willebrand factor contents, overview Homo sapiens
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3.4.24.87 hepatoma cell ADAMTS13 and von Willebrand factor contents, overview Homo sapiens
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3.4.24.87 liver secretes the enzyme, ADAMTS13 activity in hepatic carcinoma, liver cirrhosis due to viral infection, primary biliary cirrhosis, cholestasis, and biliary atresia, overview Homo sapiens
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3.4.24.87 plasma
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 Homo sapiens
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Substrates and Products (Substrate)

EC Number Substrates Comment Substrates Organism Products Comment (Products) Rev. Reac.
3.4.24.87 von Willebrand factor + H2O
-
 Homo sapiens ?
-
 ?

Synonyms

EC Number Synonyms Comment Organism
3.4.24.87 ADAMTS13
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 Homo sapiens

General Information

EC Number General Information Comment Organism
3.4.24.87 additional information decreased ADAMTS13 levels in patients after living donor liver transplantation, overview Homo sapiens
3.4.24.87 physiological function an unusually large multimer of Von Willebrand factor and ADAMTS13 may play an important role in the onset of thrombotic microangiopathy during liver transplantation. A significant reduction of ADAMTS13 and an increase of von Willebrand factor are observed in the patients with thrombotic microangiopathy-like syndrome, overview Homo sapiens