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Literature summary extracted from

  • Uemura, T.; Kaikita, K.; Yamabe, H.; Soejima, K.; Matsukawa, M.; Fuchigami, S.; Tanaka, Y.; Morihisa, K.; Enomoto, K.; Sumida, H.; Sugiyama, S.; Ogawa, H.
    Changes in plasma von Willebrand factor and ADAMTS13 levels associated with left atrial remodeling in atrial fibrillation (2009), Thromb. Res., 124, 28-32.
    View publication on PubMed

Localization

EC Number Localization Comment Organism GeneOntology No. Textmining
3.4.24.87 extracellular
-
 Homo sapiens
-
-

Natural Substrates/ Products (Substrates)

EC Number Natural Substrates Organism Comment (Nat. Sub.) Natural Products Comment (Nat. Pro.) Rev. Reac.
3.4.24.87 von Willebrand factor + H2O Homo sapiens specific cleavage of ultra-large von Willebrand factor multimers ?
-
 ?

Organism

EC Number Organism UniProt Comment Textmining
3.4.24.87 Homo sapiens
-
 paroxysmal and chronic atrial fibrillation patients and healthy controls
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Source Tissue

EC Number Source Tissue Comment Organism Textmining
3.4.24.87 plasma from paroxysmal and chronic atrial fibrillation patients and healthy controls, ADAMTS13 contents and activities, overview Homo sapiens
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Substrates and Products (Substrate)

EC Number Substrates Comment Substrates Organism Products Comment (Products) Rev. Reac.
3.4.24.87 von Willebrand factor + H2O specific cleavage of ultra-large von Willebrand factor multimers Homo sapiens ?
-
 ?

Synonyms

EC Number Synonyms Comment Organism
3.4.24.87 ADAMTS13 i.e. disintegrin-like domain and Metalloprotease with ThromboSpondin type I motif 13 Homo sapiens
3.4.24.87 vWF-cleaving protease
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 Homo sapiens

General Information

EC Number General Information Comment Organism
3.4.24.87 physiological function clinical relevance of ADAMTS13 activity is demonstrated by its reduction in thrombocytopenic purpura, metastasizing malignancies, liver disease, and the post-surgical state. Changes in plasma von Willebrand factor and ADAMTS13 levels are associated with left atrial remodeling in atrial fibrillation, phenotypes, overview Homo sapiens