BRENDA - Enzyme Database

Genetic analysis of central carbon metabolism unveils an amino acid substitution that alters maize NAD-dependent isocitrate dehydrogenase activity

Zhang, N.; Gur, A.; Gibon, Y.; Sulpice, R.; Flint-Garcia, S.; McMullen, M.D.; Stitt, M.; Buckler, E.S.; PLoS ONE 5, e9991 (2010)

Data extracted from this reference:

Cloned(Commentary)
EC Number
Commentary
Organism
1.1.1.41
DNA and amino acid sequence determination and analysis, genotyping and sequence comparison with the acient ancestor teosinte, Zea mays ssp. Parviglumis, overview
Zea mays
Natural Substrates/ Products (Substrates)
EC Number
Natural Substrates
Organism
Commentary (Nat. Sub.)
Natural Products
Commentary (Nat. Pro.)
Organism (Nat. Pro.)
Reversibility
1.1.1.41
isocitrate + NAD+
Zea mays
-
2-oxoglutarate + NADH + H+ + CO2
-
-
?
Organism
EC Number
Organism
Primary Accession No. (UniProt)
Commentary
Textmining
1.1.1.41
Zea mays
-
-
-
Substrates and Products (Substrate)
EC Number
Substrates
Commentary Substrates
Literature (Substrates)
Organism
Products
Commentary (Products)
Literature (Products)
Organism (Products)
Reversibility
1.1.1.41
isocitrate + NAD+
-
713380
Zea mays
2-oxoglutarate + NADH + H+ + CO2
-
-
-
?
Cofactor
EC Number
Cofactor
Commentary
Organism
Structure
1.1.1.41
NAD+
-
Zea mays
Cloned(Commentary) (protein specific)
EC Number
Commentary
Organism
1.1.1.41
DNA and amino acid sequence determination and analysis, genotyping and sequence comparison with the acient ancestor teosinte, Zea mays ssp. Parviglumis, overview
Zea mays
Cofactor (protein specific)
EC Number
Cofactor
Commentary
Organism
Structure
1.1.1.41
NAD+
-
Zea mays
Natural Substrates/ Products (Substrates) (protein specific)
EC Number
Natural Substrates
Organism
Commentary (Nat. Sub.)
Natural Products
Commentary (Nat. Pro.)
Organism (Nat. Pro.)
Reversibility
1.1.1.41
isocitrate + NAD+
Zea mays
-
2-oxoglutarate + NADH + H+ + CO2
-
-
?
Substrates and Products (Substrate) (protein specific)
EC Number
Substrates
Commentary Substrates
Literature (Substrates)
Organism
Products
Commentary (Products)
Literature (Products)
Organism (Products)
Reversibility
1.1.1.41
isocitrate + NAD+
-
713380
Zea mays
2-oxoglutarate + NADH + H+ + CO2
-
-
-
?
General Information
EC Number
General Information
Commentary
Organism
1.1.1.41
evolution
efficacy of association mapping for dissecting natural variation in primary metabolic pathways, the considerable genetic diversity observed in maize CCM genes underlies heritable phenotypic variation in enzyme activities and can be useful to identify putative functional sites
Zea mays
General Information (protein specific)
EC Number
General Information
Commentary
Organism
1.1.1.41
evolution
efficacy of association mapping for dissecting natural variation in primary metabolic pathways, the considerable genetic diversity observed in maize CCM genes underlies heritable phenotypic variation in enzyme activities and can be useful to identify putative functional sites
Zea mays