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Literature summary extracted from

  • Kao, C.C.; Wu, B.T.; Tsuei, Y.W.; Shih, L.J.; Kuo, Y.L.; Kao, Y.H.
    Green tea catechins: inhibitors of glycerol-3-phosphate dehydrogenase (2010), Planta Med., 76, 694-696.
    View publication on PubMed

Application

EC Number Application Comment Organism
1.1.1.8 nutrition green tea catechin (-)-epigallocatechin-3-gallate is a noncompetitive inhibitor of glycerol-3-phosphate dehydrogenase Oryctolagus cuniculus

Inhibitors

EC Number Inhibitors Comment Organism Structure
1.1.1.8 (-)-epigallocatechin-3-gallate noncompetitive Oryctolagus cuniculus

Organism

EC Number Organism UniProt Comment Textmining
1.1.1.8 Oryctolagus cuniculus
-
-
-

Source Tissue

EC Number Source Tissue Comment Organism Textmining
1.1.1.8 commercial preparation
-
 Oryctolagus cuniculus
-
1.1.1.8 muscle
-
 Oryctolagus cuniculus
-

Substrates and Products (Substrate)

EC Number Substrates Comment Substrates Organism Products Comment (Products) Rev. Reac.
1.1.1.8 dihydroxyacetone phosphate + NADH + H+
-
 Oryctolagus cuniculus sn-glycerol 3-phosphate + NAD+
-
 ?

Ki Value [mM]

EC Number Ki Value [mM] Ki Value maximum [mM] Inhibitor Comment Organism Structure
1.1.1.8 0.02
-
 (-)-epigallocatechin-3-gallate substrate dihydroxyacetone phosphate, pH 7.4, 25°C Oryctolagus cuniculus
1.1.1.8 0.02
-
 (-)-epigallocatechin-3-gallate substrate NADH, pH 7.4, 25°C Oryctolagus cuniculus

IC50 Value

EC Number IC50 Value IC50 Value Maximum Comment Organism Inhibitor Structure
1.1.1.8 0.02
-
 pH 7.4, 25°C Oryctolagus cuniculus (-)-epigallocatechin-3-gallate