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Literature summary extracted from
- Cytochrome P450-dependent methylenedioxy bridge formation in Cicer arietinum (1996), Phytochemistry, 41, 457-460.
No PubMed abstract available
Activating Compound
| EC Number | Activating Compound | Comment | Organism | Structure |
|---|---|---|---|---|
| 1.14.19.63 | O2 | absolutely required for reaction | Cicer arietinum |  |
Inhibitors
| EC Number | Inhibitors | Comment | Organism | Structure |
|---|---|---|---|---|
| 1.14.19.63 | BAS 110 | - |
Cicer arietinum | |
| 1.14.19.63 | CO | complete inhibition | Cicer arietinum | |
| 1.14.19.63 | cytochrome c | - |
Cicer arietinum | |
| 1.14.19.63 | juglone | - |
Cicer arietinum | |
| 1.14.19.63 | ketoconazole | - |
Cicer arietinum | |
| 1.14.19.63 | N2/O2 | N2/O2 atmosphere (9:1) 15-24% inhibition | Cicer arietinum | |
| 1.14.19.63 | Plumbagin | - |
Cicer arietinum | |
| 1.14.19.63 | Tetcyclacis | - |
Cicer arietinum | |
| 1.14.19.63 | Triadimefone | - |
Cicer arietinum | |
KM Value [mM]
| EC Number | KM Value [mM] | KM Value Maximum [mM] | Substrate | Comment | Organism | Structure |
|---|---|---|---|---|---|---|
| 1.14.19.63 | 0.0012 | - |
Pratensein | pH 7.5, 12°C | Cicer arietinum | |
| 1.14.19.63 | 0.002 | - |
Calycosin | pH 7.5, 12°C | Cicer arietinum | |
| 1.14.19.63 | 0.025 | - |
NADPH | pH 7.5, 12°C, 5-hydroxypseudobaptigenin synthesis | Cicer arietinum | |
| 1.14.19.63 | 0.025 | - |
NADPH | [reduced NADPH-hemoprotein reductase] | Cicer arietinum | |
| 1.14.19.63 | 0.07 | - |
NADPH | pH 7.5, 12°C, pseudobaptigenin synthesis | Cicer arietinum | |
| 1.14.19.63 | 0.07 | - |
NADPH | [reduced NADPH-hemoprotein reductase] | Cicer arietinum | |
Localization
| EC Number | Localization | Comment | Organism | GeneOntology No. | Textmining |
|---|---|---|---|---|---|
| 1.14.19.63 | microsome | - |
Cicer arietinum | - |
- |
Organism
| EC Number | Organism | UniProt | Comment | Textmining |
|---|---|---|---|---|
| 1.14.19.63 | Cicer arietinum | - |
- |
- |
Substrates and Products (Substrate)
| EC Number | Substrates | Comment Substrates | Organism | Products | Comment (Products) | Rev. | Reac. |
|---|---|---|---|---|---|---|---|
| 1.14.19.63 | calycosin + [reduced NADPH-hemoprotein reductase] + O2 | - |
Cicer arietinum | pseudobaptigenin + [oxidized NADPH-hemoprotein reductase] + H2O | - |
? | |
| 1.14.19.63 | pratensein + [reduced NADPH-hemoprotein reductase] + O2 | - |
Cicer arietinum | 5-hydroxypseudobaptigenin + [oxidized NADPH-hemoprotein reductase] + H2O | - |
? | |
Synonyms
| EC Number | Synonyms | Comment | Organism |
|---|---|---|---|
| 1.14.19.63 | 5-hydroxy-Pss | - |
Cicer arietinum |
| 1.14.19.63 | 5-hydroxypseudobaptigenin synthase | - |
Cicer arietinum |
| 1.14.19.63 | pseudobaptigenin synthase | - |
Cicer arietinum |
| 1.14.19.63 | PSS | - |
Cicer arietinum |
Temperature Optimum [°C]
| EC Number | Temperature Optimum [°C] | Temperature Optimum Maximum [°C] | Comment | Organism |
|---|---|---|---|---|
| 1.14.19.63 | 12 | - |
assay at, facilitates detection of the reactions and yields more product | Cicer arietinum |
| 1.14.19.63 | 25 | - |
- |
Cicer arietinum |
pH Optimum
| EC Number | pH Optimum Minimum | pH Optimum Maximum | Comment | Organism |
|---|---|---|---|---|
| 1.14.19.63 | 7.5 | - |
- |
Cicer arietinum |
IC50 Value
| EC Number | IC50 Value | IC50 Value Maximum | Comment | Organism | Inhibitor | Structure |
|---|---|---|---|---|---|---|
| 1.14.19.63 | 0.001 | - |
pH 7.5, 12°C | Cicer arietinum | juglone | |
| 1.14.19.63 | 0.0025 | - |
pH 7.5, 12°C | Cicer arietinum | cytochrome c | |
| 1.14.19.63 | 0.0045 | - |
pH 7.5, 12°C | Cicer arietinum | Plumbagin | |
| 1.14.19.63 | 0.012 | - |
pH 7.5, 12°C | Cicer arietinum | Plumbagin | |
| 1.14.19.63 | 0.04 | - |
pH 7.5, 12°C | Cicer arietinum | ketoconazole | |
| 1.14.19.63 | 0.06 | - |
pH 7.5, 12°C | Cicer arietinum | ketoconazole | |
| 1.14.19.63 | 0.09 | - |
pH 7.5, 12°C | Cicer arietinum | Tetcyclacis | |
| 1.14.19.63 | 0.12 | - |
pH 7.5, 12°C | Cicer arietinum | Tetcyclacis | |
| 1.14.19.63 | 0.35 | - |
pH 7.5, 12°C | Cicer arietinum | BAS 110 | |
| 1.14.19.63 | 0.36 | - |
pH 7.5, 12°C | Cicer arietinum | Triadimefone | |
| 1.14.19.63 | 0.4 | - |
pH 7.5, 12°C | Cicer arietinum | BAS 110 | |
| 1.14.19.63 | 0.4 | - |
pH 7.5, 12°C | Cicer arietinum | Triadimefone | |
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