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Literature summary extracted from

  • Dreiseitel, A.; Korte, G.; Schreier, P.; Oehme, A.; Locher, S.; Domani, M.; Hajak, G.; Sand, P.G.
    Berry anthocyanins and their aglycons inhibit monoamine oxidases A and B (2009), Pharmacol. Res., 59, 306-311.
    View publication on PubMed

Inhibitors

EC Number Inhibitors Comment Organism Structure
1.4.3.4 3-(4-hydroxyphenyl)propionic acid
-
Homo sapiens
1.4.3.4 3-hydroxyphenylacetic acid
-
Homo sapiens
1.4.3.4 4-hydroxyphenylacetic acid
-
Homo sapiens
1.4.3.4 cyanidin competitive interaction of cyanidin with MAO A plus a mixed competitive and non-competitive mode of interaction of cyanidin with MAO B Homo sapiens
1.4.3.4 cyanidin-3,5-diglucoside
-
Homo sapiens
1.4.3.4 cyanidin-3-O-beta-D-galactoside
-
Homo sapiens
1.4.3.4 cyanidin-3-O-beta-D-glucoside mixed competitive and non-competitive mode of interaction with both enzyme isozymes Homo sapiens
1.4.3.4 cyanidin-3-O-beta-D-rutinoside
-
Homo sapiens
1.4.3.4 delphinidin
-
Homo sapiens
1.4.3.4 delphinidin-3-O-beta-D-glucoside
-
Homo sapiens
1.4.3.4 malvidin
-
Homo sapiens
1.4.3.4 malvidin 3-O,5-O-di-beta-D-glucoside
-
Homo sapiens
1.4.3.4 malvidin-3-O-beta-D-galactoside
-
Homo sapiens
1.4.3.4 malvidin-3-O-beta-D-glucoside
-
Homo sapiens
1.4.3.4 additional information 25 anthocyanidins, anthocyanidin-3-glycosides, anthocyanidin-3,5-diglucosides, proanthocyanidins, and phenolic metabolites are examined as MAO inhibitors, overview Homo sapiens
1.4.3.4 pelargonidin
-
Homo sapiens
1.4.3.4 pelargonidin 3-O,5-O-di-beta-D-glucoside
-
Homo sapiens
1.4.3.4 peonidin
-
Homo sapiens
1.4.3.4 peonidin-3-O-beta-D-glucoside
-
Homo sapiens
1.4.3.4 petunidin
-
Homo sapiens
1.4.3.4 syringic acid
-
Homo sapiens
1.4.3.4 vanillic acid
-
Homo sapiens

Localization

EC Number Localization Comment Organism GeneOntology No. Textmining
1.4.3.4 mitochondrion
-
Homo sapiens 5739
-

Organism

EC Number Organism UniProt Comment Textmining
1.4.3.4 Homo sapiens
-
-
-

Source Tissue

EC Number Source Tissue Comment Organism Textmining
1.4.3.4 brain
-
Homo sapiens
-
1.4.3.4 commercial preparation recombinant isozymes MAO A and MAO B, expressed in baculovirus-infected insect cells BTI-TN-5B1-4 Homo sapiens
-

Synonyms

EC Number Synonyms Comment Organism
1.4.3.4 MAO-A
-
Homo sapiens
1.4.3.4 MAO-B
-
Homo sapiens
1.4.3.4 monoamine oxidase A
-
Homo sapiens
1.4.3.4 monoamine oxidase B
-
Homo sapiens

Ki Value [mM]

EC Number Ki Value [mM] Ki Value maximum [mM] Inhibitor Comment Organism Structure
1.4.3.4 0.0204
-
cyanidin pH not specified in the publication, temperature not specified in the publication, MAO-A Homo sapiens
1.4.3.4 0.0317
-
cyanidin pH not specified in the publication, temperature not specified in the publication, MAO-B Homo sapiens
1.4.3.4 0.0474
-
cyanidin-3-O-beta-D-glucoside pH not specified in the publication, temperature not specified in the publication, MAO-A Homo sapiens
1.4.3.4 0.0586
-
cyanidin pH not specified in the publication, temperature not specified in the publication, MAO-B Homo sapiens
1.4.3.4 0.0611
-
cyanidin-3-O-beta-D-glucoside pH not specified in the publication, temperature not specified in the publication, MAO-B Homo sapiens

IC50 Value

EC Number IC50 Value IC50 Value Maximum Comment Organism Inhibitor Structure
1.4.3.4 0.0187
-
pH not specified in the publication, temperature not specified in the publication, MAO-B Homo sapiens malvidin
1.4.3.4 0.0221
-
pH not specified in the publication, temperature not specified in the publication, MAO-A Homo sapiens malvidin
1.4.3.4 0.0221
-
pH not specified in the publication, temperature not specified in the publication, MAO-B Homo sapiens peonidin
1.4.3.4 0.0268
-
pH not specified in the publication, temperature not specified in the publication, MAO-A Homo sapiens pelargonidin
1.4.3.4 0.0294
-
pH not specified in the publication, temperature not specified in the publication, MAO-A Homo sapiens delphinidin-3-O-beta-D-glucoside
1.4.3.4 0.0295
-
pH not specified in the publication, temperature not specified in the publication, MAO-A Homo sapiens cyanidin
1.4.3.4 0.0305
-
pH not specified in the publication, temperature not specified in the publication, MAO-A Homo sapiens peonidin
1.4.3.4 0.0314
-
pH not specified in the publication, temperature not specified in the publication, MAO-B Homo sapiens delphinidin-3-O-beta-D-glucoside
1.4.3.4 0.0315
-
pH not specified in the publication, temperature not specified in the publication, MAO-A Homo sapiens petunidin
1.4.3.4 0.0332
-
pH not specified in the publication, temperature not specified in the publication, MAO-A Homo sapiens cyanidin-3-O-beta-D-rutinoside
1.4.3.4 0.0341
-
pH not specified in the publication, temperature not specified in the publication, MAO-B Homo sapiens malvidin-3-O-beta-D-galactoside
1.4.3.4 0.0343
-
pH not specified in the publication, temperature not specified in the publication, MAO-A Homo sapiens cyanidin-3-O-beta-D-glucoside
1.4.3.4 0.0348
-
pH not specified in the publication, temperature not specified in the publication, MAO-A Homo sapiens delphinidin
1.4.3.4 0.0351
-
pH not specified in the publication, temperature not specified in the publication, MAO-B Homo sapiens cyanidin-3-O-beta-D-rutinoside
1.4.3.4 0.0359
-
pH not specified in the publication, temperature not specified in the publication, MAO-A Homo sapiens cyanidin-3-O-beta-D-galactoside
1.4.3.4 0.0368
-
pH not specified in the publication, temperature not specified in the publication, MAO-B Homo sapiens malvidin-3-O-beta-D-glucoside
1.4.3.4 0.038
-
pH not specified in the publication, temperature not specified in the publication, MAO-B Homo sapiens delphinidin
1.4.3.4 0.0381
-
pH not specified in the publication, temperature not specified in the publication, MAO-A Homo sapiens peonidin-3-O-beta-D-glucoside
1.4.3.4 0.0393
-
pH not specified in the publication, temperature not specified in the publication, MAO-A Homo sapiens malvidin-3-O-beta-D-galactoside
1.4.3.4 0.0407
-
pH not specified in the publication, temperature not specified in the publication, MAO-B Homo sapiens peonidin-3-O-beta-D-glucoside
1.4.3.4 0.0426
-
pH not specified in the publication, temperature not specified in the publication, MAO-B Homo sapiens pelargonidin
1.4.3.4 0.0432
-
pH not specified in the publication, temperature not specified in the publication, MAO-B Homo sapiens petunidin
1.4.3.4 0.0464
-
pH not specified in the publication, temperature not specified in the publication, MAO-B Homo sapiens cyanidin-3-O-beta-D-galactoside
1.4.3.4 0.0478
-
pH not specified in the publication, temperature not specified in the publication, MAO-A Homo sapiens malvidin-3-O-beta-D-glucoside
1.4.3.4 0.0616
-
pH not specified in the publication, temperature not specified in the publication, MAO-A Homo sapiens malvidin 3-O,5-O-di-beta-D-glucoside
1.4.3.4 0.0733
-
pH not specified in the publication, temperature not specified in the publication, MAO-B Homo sapiens malvidin 3-O,5-O-di-beta-D-glucoside
1.4.3.4 0.113
-
pH not specified in the publication, temperature not specified in the publication, MAO-A Homo sapiens cyanidin-3,5-diglucoside
1.4.3.4 0.1173
-
pH not specified in the publication, temperature not specified in the publication, MAO-A Homo sapiens pelargonidin 3-O,5-O-di-beta-D-glucoside
1.4.3.4 0.152
-
pH not specified in the publication, temperature not specified in the publication, MAO-B Homo sapiens cyanidin-3,5-diglucoside
1.4.3.4 0.242
-
pH not specified in the publication, temperature not specified in the publication, MAO-B Homo sapiens pelargonidin 3-O,5-O-di-beta-D-glucoside
1.4.3.4 3.89
-
pH not specified in the publication, temperature not specified in the publication, MAO-A Homo sapiens vanillic acid
1.4.3.4 4.16
-
pH not specified in the publication, temperature not specified in the publication, MAO-A Homo sapiens syringic acid
1.4.3.4 11.52
-
pH not specified in the publication, temperature not specified in the publication, MAO-A Homo sapiens 3-(4-hydroxyphenyl)propionic acid
1.4.3.4 17.75
-
pH not specified in the publication, temperature not specified in the publication, MAO-A Homo sapiens 3-hydroxyphenylacetic acid
1.4.3.4 20.28
-
pH not specified in the publication, temperature not specified in the publication, MAO-A Homo sapiens 4-hydroxyphenylacetic acid