EC Number | Inhibitors | Comment | Organism | Structure |
---|---|---|---|---|
1.6.5.2 | dicoumarol | - |
Homo sapiens |
EC Number | Organism | UniProt | Comment | Textmining |
---|---|---|---|---|
1.6.5.2 | Homo sapiens | - |
- |
- |
EC Number | Source Tissue | Comment | Organism | Textmining |
---|---|---|---|---|
1.6.5.2 | A-2780 cell | - |
Homo sapiens | - |
1.6.5.2 | A-549 cell | - |
Homo sapiens | - |
1.6.5.2 | AsPC-1 cell | - |
Homo sapiens | - |
1.6.5.2 | BT-474 cell | - |
Homo sapiens | - |
1.6.5.2 | DAUDI cell | - |
Homo sapiens | - |
1.6.5.2 | HCC-827 cell | - |
Homo sapiens | - |
1.6.5.2 | HCT-116 cell | - |
Homo sapiens | - |
1.6.5.2 | HT-29 cell | - |
Homo sapiens | - |
1.6.5.2 | IGROV-1 cell | - |
Homo sapiens | - |
1.6.5.2 | JIMT-1 cell | - |
Homo sapiens | - |
1.6.5.2 | L3.6pl cell | - |
Homo sapiens | - |
1.6.5.2 | MCF-7 cell | - |
Homo sapiens | - |
1.6.5.2 | MDA-MB-231 cell | - |
Homo sapiens | - |
1.6.5.2 | additional information | NQO1 is not detected in the acute myelogenous leukemia cell line MV4:11 or in the non-small cell lung cancer cell line HCC-4006 | Homo sapiens | - |
1.6.5.2 | NCI-H1650 cell | - |
Homo sapiens | - |
1.6.5.2 | NCI-H1975 cell | - |
Homo sapiens | - |
1.6.5.2 | NCI-H460 cell | - |
Homo sapiens | - |
1.6.5.2 | SK-BR-3 cell | - |
Homo sapiens | - |
1.6.5.2 | SKOV-3 cell | - |
Homo sapiens | - |
1.6.5.2 | SW-480 cell | - |
Homo sapiens | - |
EC Number | Substrates | Comment Substrates | Organism | Products | Comment (Products) | Rev. | Reac. |
---|---|---|---|---|---|---|---|
1.6.5.2 | menadione + NADH | - |
Homo sapiens | reduced menadione + NAD+ | - |
? |
EC Number | Synonyms | Comment | Organism |
---|---|---|---|
1.6.5.2 | NAD(P)H:quinone oxidoreductase 1 | - |
Homo sapiens |
1.6.5.2 | NQO1 | - |
Homo sapiens |
EC Number | Cofactor | Comment | Organism | Structure |
---|---|---|---|---|
1.6.5.2 | NADH | - |
Homo sapiens | |
1.6.5.2 | NADPH | - |
Homo sapiens |
EC Number | General Information | Comment | Organism |
---|---|---|---|
1.6.5.2 | physiological function | artificial overexpression of NQO1 is able to increase the level of hydroquinone and cell sensitivity to IPI-504. NQO1 activity is not a determinant of IPI-504 activity | Homo sapiens |