EC Number | Activating Compound | Comment | Organism | Structure |
---|---|---|---|---|
5.6.1.2 | microtubule | the ATPase activities of the two-headed I1 dynein and the single-headed I1beta dynein are activated by microtubules, whereas the kcat of I1beta is higher than that of the intact I1d dynein | Chlamydomonas sp. | |
5.6.1.2 | additional information | I1alpha does not show any microtubule activation on its ATPase activity | Chlamydomonas sp. |
EC Number | KM Value [mM] | KM Value Maximum [mM] | Substrate | Comment | Organism | Structure |
---|---|---|---|---|---|---|
5.6.1.2 | additional information | - |
ATP | the I1alpha complex has a higher Km value than either I1 or I1beta dynein complex, indicating a lower affinity for ATP | Chlamydomonas sp. | |
5.6.1.2 | additional information | - |
additional information | the steady-state ATPase rates fit the Michaelis-Menten kinetics | Chlamydomonas sp. |
EC Number | Localization | Comment | Organism | GeneOntology No. | Textmining |
---|---|---|---|---|---|
5.6.1.2 | cytoplasm | - |
Chlamydomonas sp. | 5737 | - |
EC Number | Organism | UniProt | Comment | Textmining |
---|---|---|---|---|
5.6.1.2 | Chlamydomonas sp. | - |
several strains | - |
EC Number | Source Tissue | Comment | Organism | Textmining |
---|
EC Number | Specific Activity Minimum [µmol/min/mg] | Specific Activity Maximum [µmol/min/mg] | Comment | Organism |
---|---|---|---|---|
5.6.1.2 | additional information | - |
I1beta complex has 7fold higher ATPase activity and microtubule gliding motility compared to Ialpha complex. The ATPase activity of the two-headed I1 dynein is lower than the combined value of its I1alpha and I1beta motor domains | Chlamydomonas sp. |
EC Number | Substrates | Comment Substrates | Organism | Products | Comment (Products) | Rev. | Reac. |
---|---|---|---|---|---|---|---|
5.6.1.2 | ATP + H2O + a dynein associated with a microtubule at position n | - |
Chlamydomonas sp. | ADP + phosphate + a dynein associated with a microtubule at position n-1 (toward the minus end) | - |
? |
EC Number | Synonyms | Comment | Organism |
---|---|---|---|
5.6.1.2 | dynein I1 | a two-headed inner dynein arm for regulation of flagellar blending | Chlamydomonas sp. |
5.6.1.2 | Ialpha complex | dynein I1, single-headed inner dynein arm | Chlamydomonas sp. |
5.6.1.2 | Ibeta complex | dynein I1 inner dynein arm | Chlamydomonas sp. |
EC Number | Turnover Number Minimum [1/s] | Turnover Number Maximum [1/s] | Substrate | Comment | Organism | Structure |
---|---|---|---|---|---|---|
5.6.1.2 | additional information | - |
ATP | I1beta has a higher turnover number compared to the two-headed wild-type I1 dynein, whereas the tunrover number of I1alpha is approximately 1/8 the one of I1beta | Chlamydomonas sp. |
EC Number | General Information | Comment | Organism |
---|---|---|---|
5.6.1.2 | physiological function | a two-headed inner dynein arm for regulation of flagellar blending | Chlamydomonas sp. |