EC Number | Inhibitors | Comment | Organism | Structure |
---|---|---|---|---|
1.14.13.8 | Methimazole | - |
Bos taurus | |
1.14.13.8 | Methimazole | - |
Oryctolagus cuniculus | |
1.14.13.8 | Methimazole | - |
Sus scrofa | |
1.14.13.8 | trimethylamine | - |
Bos taurus | |
1.14.13.8 | trimethylamine | - |
Oryctolagus cuniculus | |
1.14.13.8 | trimethylamine | - |
Sus scrofa |
EC Number | KM Value [mM] | KM Value Maximum [mM] | Substrate | Comment | Organism | Structure |
---|---|---|---|---|---|---|
1.14.13.8 | additional information | - |
additional information | Michaelis-Menten kinetics, overview | Sus scrofa | |
1.14.13.8 | additional information | - |
additional information | Michaelis-Menten kinetics, overview | Bos taurus | |
1.14.13.8 | additional information | - |
additional information | Michaelis-Menten kinetics, overview | Oryctolagus cuniculus |
EC Number | Localization | Comment | Organism | GeneOntology No. | Textmining |
---|---|---|---|---|---|
1.14.13.8 | microsome | - |
Sus scrofa | - |
- |
1.14.13.8 | microsome | - |
Bos taurus | - |
- |
1.14.13.8 | microsome | - |
Oryctolagus cuniculus | - |
- |
EC Number | Natural Substrates | Organism | Comment (Nat. Sub.) | Natural Products | Comment (Nat. Pro.) | Rev. | Reac. |
---|---|---|---|---|---|---|---|
1.14.13.8 | benzydamine + NADPH + H+ + O2 | Sus scrofa | - |
benzydamine N-oxide + NADP+ + H2O | - |
? | |
1.14.13.8 | benzydamine + NADPH + H+ + O2 | Bos taurus | - |
benzydamine N-oxide + NADP+ + H2O | - |
? | |
1.14.13.8 | benzydamine + NADPH + H+ + O2 | Oryctolagus cuniculus | - |
benzydamine N-oxide + NADP+ + H2O | - |
? | |
1.14.13.8 | additional information | Sus scrofa | benzydamine is a weak base and an indazole derivative with analgesic and antipyretic properties used in human and veterinary medicine, it is metabolized to a wide range of metabolites. One of the main metabolites, benzydamine N-oxide is produced in the liver and brain by flavin-containing monooxygenases | ? | - |
? | |
1.14.13.8 | additional information | Bos taurus | benzydamine is a weak base and an indazole derivative with analgesic and antipyretic properties used in human and veterinary medicine, it is metabolized to a wide range of metabolites. One of the main metabolites, benzydamine N-oxide is produced in the liver and brain by flavin-containing monooxygenases | ? | - |
? | |
1.14.13.8 | additional information | Oryctolagus cuniculus | benzydamine is a weak base and an indazole derivative with analgesic and antipyretic properties used in human and veterinary medicine, it is metabolized to a wide range of metabolites. One of the main metabolites, benzydamine N-oxide is produced in the liver and brain by flavin-containing monooxygenases | ? | - |
? |
EC Number | Organism | UniProt | Comment | Textmining |
---|---|---|---|---|
1.14.13.8 | Bos taurus | - |
- |
- |
1.14.13.8 | Oryctolagus cuniculus | - |
- |
- |
1.14.13.8 | Sus scrofa | - |
- |
- |
EC Number | Source Tissue | Comment | Organism | Textmining |
---|---|---|---|---|
1.14.13.8 | brain | - |
Sus scrofa | - |
1.14.13.8 | brain | - |
Bos taurus | - |
1.14.13.8 | brain | - |
Oryctolagus cuniculus | - |
1.14.13.8 | liver | - |
Sus scrofa | - |
1.14.13.8 | liver | - |
Bos taurus | - |
1.14.13.8 | liver | - |
Oryctolagus cuniculus | - |
EC Number | Substrates | Comment Substrates | Organism | Products | Comment (Products) | Rev. | Reac. |
---|---|---|---|---|---|---|---|
1.14.13.8 | benzydamine + NADPH + H+ + O2 | - |
Sus scrofa | benzydamine N-oxide + NADP+ + H2O | - |
? | |
1.14.13.8 | benzydamine + NADPH + H+ + O2 | - |
Bos taurus | benzydamine N-oxide + NADP+ + H2O | - |
? | |
1.14.13.8 | benzydamine + NADPH + H+ + O2 | - |
Oryctolagus cuniculus | benzydamine N-oxide + NADP+ + H2O | - |
? | |
1.14.13.8 | additional information | benzydamine is a weak base and an indazole derivative with analgesic and antipyretic properties used in human and veterinary medicine, it is metabolized to a wide range of metabolites. One of the main metabolites, benzydamine N-oxide is produced in the liver and brain by flavin-containing monooxygenases | Sus scrofa | ? | - |
? | |
1.14.13.8 | additional information | benzydamine is a weak base and an indazole derivative with analgesic and antipyretic properties used in human and veterinary medicine, it is metabolized to a wide range of metabolites. One of the main metabolites, benzydamine N-oxide is produced in the liver and brain by flavin-containing monooxygenases | Bos taurus | ? | - |
? | |
1.14.13.8 | additional information | benzydamine is a weak base and an indazole derivative with analgesic and antipyretic properties used in human and veterinary medicine, it is metabolized to a wide range of metabolites. One of the main metabolites, benzydamine N-oxide is produced in the liver and brain by flavin-containing monooxygenases | Oryctolagus cuniculus | ? | - |
? |
EC Number | Synonyms | Comment | Organism |
---|---|---|---|
1.14.13.8 | FMO | - |
Sus scrofa |
1.14.13.8 | FMO | - |
Bos taurus |
1.14.13.8 | FMO | - |
Oryctolagus cuniculus |
EC Number | Temperature Optimum [°C] | Temperature Optimum Maximum [°C] | Comment | Organism |
---|---|---|---|---|
1.14.13.8 | 37 | - |
assay at | Sus scrofa |
1.14.13.8 | 37 | - |
assay at | Bos taurus |
1.14.13.8 | 37 | - |
assay at | Oryctolagus cuniculus |
EC Number | pH Optimum Minimum | pH Optimum Maximum | Comment | Organism |
---|---|---|---|---|
1.14.13.8 | 7.4 | - |
assay at | Sus scrofa |
1.14.13.8 | 7.4 | - |
assay at | Bos taurus |
1.14.13.8 | 7.4 | - |
assay at | Oryctolagus cuniculus |
EC Number | Cofactor | Comment | Organism | Structure |
---|---|---|---|---|
1.14.13.8 | flavin | - |
Sus scrofa | |
1.14.13.8 | flavin | - |
Bos taurus | |
1.14.13.8 | flavin | - |
Oryctolagus cuniculus | |
1.14.13.8 | NADPH | - |
Sus scrofa | |
1.14.13.8 | NADPH | - |
Bos taurus | |
1.14.13.8 | NADPH | - |
Oryctolagus cuniculus |
EC Number | Ki Value [mM] | Ki Value maximum [mM] | Inhibitor | Comment | Organism | Structure |
---|---|---|---|---|---|---|
1.14.13.8 | additional information | - |
additional information | inhibition kinetics, overview | Sus scrofa | |
1.14.13.8 | additional information | - |
additional information | inhibition kinetics, overview | Bos taurus | |
1.14.13.8 | additional information | - |
additional information | inhibition kinetics, overview | Oryctolagus cuniculus |