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Literature summary extracted from

  • Walter, W.J.; Brenner, B.; Steffen, W.
    Cytoplasmic dynein is not a conventional processive motor (2010), J. Struct. Biol., 170, 266-269.
    View publication on PubMed

Localization

EC Number Localization Comment Organism GeneOntology No. Textmining
5.6.1.2 cytoplasm
-
 Sus scrofa 5737
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Organism

EC Number Organism UniProt Comment Textmining
5.6.1.2 Sus scrofa
-
-
-

Source Tissue

EC Number Source Tissue Comment Organism Textmining
5.6.1.2 brain
-
 Sus scrofa
-

Specific Activity [micromol/min/mg]

EC Number Specific Activity Minimum [µmol/min/mg] Specific Activity Maximum [µmol/min/mg] Comment Organism
5.6.1.2 additional information
-
 at 0.001 mM ATP cytoplasm dynein only performed discrete single binding events. At this low ATP concentration dynein behaves as a non-processive motor. At low ATP dynein undergoes a -8 nm apparent working stroke and the lifetime of these binding events depends on ATP concentration Sus scrofa

Substrates and Products (Substrate)

EC Number Substrates Comment Substrates Organism Products Comment (Products) Rev. Reac.
5.6.1.2 ATP + H2O + a dynein associated with a microtubule at position n the cytoplasmic dynein is a non-processive motor at low ATP concentrations. Processivity can be restored even in the absence of dynactin by increasing the ATP concentration to 0.1 mM Sus scrofa ADP + phosphate + a dynein associated with a microtubule at position n-1 (toward the minus end)
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 ?

Synonyms

EC Number Synonyms Comment Organism
5.6.1.2 dynein
-
 Sus scrofa