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Literature summary extracted from

  • Tagawa, N.; Yuda, R.; Kubota, S.; Wakabayashi, M.; Yamaguchi, Y.; Kiyonaga, D.; Mori, N.; Minamitani, E.; Masuzaki, H.; Kobayashi, Y.
    17Beta-estradiol inhibits 11beta-hydroxysteroid dehydrogenase type 1 activity in rodent adipocytes (2009), J. Endocrinol., 202, 131-139.
    View publication on PubMed

Inhibitors

EC Number Inhibitors Comment Organism Structure
1.1.1.146 17beta-estradiol non-competitive Mus musculus
1.1.1.146 17beta-estradiol
-
 Rattus norvegicus
1.1.1.146 17beta-estradiol-3-acetate
-
 Mus musculus

KM Value [mM]

EC Number KM Value [mM] KM Value Maximum [mM] Substrate Comment Organism Structure
1.1.1.146 0.00025
-
 11-Dehydrocorticosterone pH 7.4, 37°C Mus musculus

Organism

EC Number Organism UniProt Comment Textmining
1.1.1.146 Mus musculus
-
-
-
1.1.1.146 Rattus norvegicus
-
-
-

Source Tissue

EC Number Source Tissue Comment Organism Textmining
1.1.1.146 3T3-L1 cell
-
 Mus musculus
-
1.1.1.146 adipocyte
-
 Rattus norvegicus
-

Substrates and Products (Substrate)

EC Number Substrates Comment Substrates Organism Products Comment (Products) Rev. Reac.
1.1.1.146 11-dehydrocorticosterone + NADPH + H+
-
 Mus musculus corticosterone + NADP+
-
 ?
1.1.1.146 11-dehydrocorticosterone + NADPH + H+
-
 Rattus norvegicus corticosterone + NADP+
-
 ?

Synonyms

EC Number Synonyms Comment Organism
1.1.1.146 11-oxoreductase
-
 Mus musculus
1.1.1.146 11-oxoreductase
-
 Rattus norvegicus
1.1.1.146 11beta-hydroxysteroid dehydrogenase type 1
-
 Mus musculus
1.1.1.146 11beta-hydroxysteroid dehydrogenase type 1
-
 Rattus norvegicus