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Literature summary extracted from

  • Wassermann, G.E.; Olivera-Severo, D.; Uberti, A.F.; Carlini, C.R.
    Helicobacter pylori urease activates blood platelets through a lipoxygenase-mediated pathway (2010), J. Cell. Mol. Med., 14, 2025-2034.
    View publication on PubMedView publication on EuropePMC

Cloned(Commentary)

EC Number Cloned (Comment) Organism
3.5.1.5 recombinantly expressed in Escherichia coli Helicobacter pylori

Molecular Weight [Da]

EC Number Molecular Weight [Da] Molecular Weight Maximum [Da] Comment Organism
3.5.1.5 30000
-
 SDS-PAGE, two major bands at 30 kDa and 60 kDa Helicobacter pylori
3.5.1.5 60000
-
 SDS-PAGE, two major bands at 30 kDa and 60 kDa Helicobacter pylori

Organism

EC Number Organism UniProt Comment Textmining
3.5.1.5 Helicobacter pylori
-
-
-

Purification (Commentary)

EC Number Purification (Comment) Organism
3.5.1.5 using ammonium sulfate precipitation, dialysis, and anion exchange chromatography Helicobacter pylori

Source Tissue

EC Number Source Tissue Comment Organism Textmining

Synonyms

EC Number Synonyms Comment Organism
3.5.1.5 HPU
-
 Helicobacter pylori
3.5.1.5 urease
-
 Helicobacter pylori

Temperature Optimum [°C]

EC Number Temperature Optimum [°C] Temperature Optimum Maximum [°C] Comment Organism
3.5.1.5 37
-
 assay at Helicobacter pylori

pH Optimum

EC Number pH Optimum Minimum pH Optimum Maximum Comment Organism
3.5.1.5 7.5
-
 assay at Helicobacter pylori

General Information

EC Number General Information Comment Organism
3.5.1.5 physiological function effects of urease added to rabbit platelets are assessed turbidimetrically. Fluorescein-labelled HPU bound to platelets but not to erythrocytes. HPU induces aggregation of rabbit platelets accompanied by ATP secretion. No correlation is found between platelet activation and ureolytic activity of HPU Helicobacter pylori