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Literature summary extracted from

  • Abrahan, C.E.; Miranda, G.E.; Agnolazza, D.L.; Politi, L.E.; Rotstein, N.P.
    Synthesis of sphingosine is essential for oxidative stress-induced apoptosis of photoreceptors (2010), Invest. Ophthalmol. Vis. Sci., 51, 1171-1180.
    View publication on PubMed

Activating Compound

EC Number Activating Compound Comment Organism Structure
3.5.1.23 paraquat
-
 Rattus norvegicus

Natural Substrates/ Products (Substrates)

EC Number Natural Substrates Organism Comment (Nat. Sub.) Natural Products Comment (Nat. Pro.) Rev. Reac.
3.5.1.23 ceramide + H2O Rattus norvegicus
-
 sphingosine + a fatty acid sphongosine is an apoptosis mediator ?

Organism

EC Number Organism UniProt Comment Textmining
3.5.1.23 Rattus norvegicus
-
 albino Wistar rats
-

Source Tissue

EC Number Source Tissue Comment Organism Textmining
3.5.1.23 neuron
-
 Rattus norvegicus
-
3.5.1.23 photoreceptor
-
 Rattus norvegicus
-
3.5.1.23 retina
-
 Rattus norvegicus
-

Substrates and Products (Substrate)

EC Number Substrates Comment Substrates Organism Products Comment (Products) Rev. Reac.
3.5.1.23 ceramide + H2O
-
 Rattus norvegicus sphingosine + a fatty acid
-
 ?
3.5.1.23 ceramide + H2O
-
 Rattus norvegicus sphingosine + a fatty acid sphongosine is an apoptosis mediator ?

Synonyms

EC Number Synonyms Comment Organism
3.5.1.23 alkaline ceramidase
-
 Rattus norvegicus

General Information

EC Number General Information Comment Organism
3.5.1.23 physiological function synthesis of sphingosine is essential for oxidative stress-induced apoptosis of photoreceptors, pathway regulation, overview Rattus norvegicus