Any feedback?
Please rate this page
(literature.php)
(0/150)

BRENDA support

Literature summary extracted from

  • Kosugi, N.; Tsurutani, Y.; Isonishi, A.; Hori, Y.; Matsumoto, M.; Fujimura, Y.
    Influenza A infection triggers thrombotic thrombocytopenic purpura by producing the anti-ADAMTS13 IgG inhibitor (2010), Intern. Med., 49, 689-693.
    View publication on PubMed

Inhibitors

EC Number Inhibitors Comment Organism Structure
3.4.24.87 additional information influenza A infection is sufficient to trigger thrombotic thrombocytopenic purpura by producing the anti-ADAMTS13 IgG inhibitor, overview Homo sapiens

Localization

EC Number Localization Comment Organism GeneOntology No. Textmining
3.4.24.87 extracellular
-
 Homo sapiens
-
-

Natural Substrates/ Products (Substrates)

EC Number Natural Substrates Organism Comment (Nat. Sub.) Natural Products Comment (Nat. Pro.) Rev. Reac.
3.4.24.87 von Willebrand factor + H2O Homo sapiens ADAMTS13 specifically cleaves von Willebrand factor multimers at the site of the Tyr1605-Met1606 bond of the VWF-A2 domain von Willebrand factor fragments
-
 ?

Organism

EC Number Organism UniProt Comment Textmining
3.4.24.87 Homo sapiens
-
-
-

Source Tissue

EC Number Source Tissue Comment Organism Textmining
3.4.24.87 plasma
-
 Homo sapiens
-

Substrates and Products (Substrate)

EC Number Substrates Comment Substrates Organism Products Comment (Products) Rev. Reac.
3.4.24.87 von Willebrand factor + H2O
-
 Homo sapiens von Willebrand factor fragments
-
 ?
3.4.24.87 von Willebrand factor + H2O ADAMTS13 specifically cleaves von Willebrand factor multimers at the site of the Tyr1605-Met1606 bond of the VWF-A2 domain Homo sapiens von Willebrand factor fragments
-
 ?

General Information

EC Number General Information Comment Organism
3.4.24.87 additional information Influenza A infection triggers thrombotic thrombocytopenic purpura by producing the anti-ADAMTS13 IgG inhibitor, overview Homo sapiens