Literature summary extracted from

Kong, Y.; Guo, Q.; Yu, C.; Dong, D.; Zhao, J.; Cai, C.; Hou, L.; Song, X.; Fu, L.; Xu, J.; Chen, W.
Fusion protein of DELTA 27LFn and EFn has the potential as a novel anthrax toxin inhibitor (2009), FEBS Lett., 583, 1257-1260.

Inhibitors

EC Number	Inhibitors	Comment	Organism	Structure
3.4.24.83	additional information	fusion protein of N-terminal 27 amino acids deletion of protective antigen-binding domain of anthrax lethal factor Delta27LFn and protective antigen-binding domain of edema factor is a 62-fold more potent toxin inhibitor than protective antigen-binding domain of anthrax lethal factor or protective antigen-binding domain of edema factor in a cell model of intoxication, and this increased activity corresponds to a 39-fold higher protective antigen-binding affinity by Biacore analysis. The fusion protein can protect the highly susceptible Fischer 344 rats from anthrax lethal toxin challenge	Bacillus anthracis

Organism

EC Number	Organism	UniProt	Comment	Textmining
3.4.24.83	Bacillus anthracis	-	-	-

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Release 2023.1 (January 2023)