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Literature summary extracted from

  • Lee, F.P.; Shih, C.M.; Shen, H.Y.; Chen, C.M.; Chen, C.M.; Ko, W.C.
    Ayanin, a non-selective phosphodiesterase 1-4 inhibitor, effectively suppresses ovalbumin-induced airway hyperresponsiveness without affecting xylazine/ketamine-induced anesthesia (2010), Eur. J. Pharmacol., 635, 198-203.
    View publication on PubMed

Inhibitors

EC Number Inhibitors Comment Organism Structure
3.1.4.53 AWD 12-281 selective PDE4 inhibitor Mus musculus
3.1.4.53 ayanin i.e. quercetin-3,7,4'-O-trimethylether, non-selective phosphodiesterase 1-4 inhibitor Mus musculus
3.1.4.53 cilomilast
-
 Mus musculus
3.1.4.53 Ro 20-1724 selective PDE4 inhibitor Mus musculus
3.1.4.53 roflumilast
-
 Mus musculus
3.1.4.53 rolipram PDE4-selective inhibitor Mus musculus

Natural Substrates/ Products (Substrates)

EC Number Natural Substrates Organism Comment (Nat. Sub.) Natural Products Comment (Nat. Pro.) Rev. Reac.
3.1.4.53 3',5'-cAMP + H2O Mus musculus
-
 5'-AMP
-
 ?

Organism

EC Number Organism UniProt Comment Textmining
3.1.4.53 Mus musculus
-
-
-

Substrates and Products (Substrate)

EC Number Substrates Comment Substrates Organism Products Comment (Products) Rev. Reac.
3.1.4.53 3',5'-cAMP + H2O
-
 Mus musculus 5'-AMP
-
 ?

Synonyms

EC Number Synonyms Comment Organism
3.1.4.53 PDE4
-
 Mus musculus
3.1.4.53 phosphodiesterase 4
-
 Mus musculus