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Literature summary extracted from
- Etazolate improves performance in a foraging and homing task in aged rats (2010), Eur. J. Pharmacol., 634, 95-100.
Activating Compound
| EC Number | Activating Compound | Comment | Organism | Structure |
|---|---|---|---|---|
| 3.4.23.46 | etazolate | i.e. 1-ethyl-4-(N'-isopropylidene-hydrazino)-1H-pyrazolo[3,4-b]pyridine-5-carboxylic acid ethyl ester, stimulates alpha-secretase activity | Rattus norvegicus |  |
Natural Substrates/ Products (Substrates)
| EC Number | Natural Substrates | Organism | Comment (Nat. Sub.) | Natural Products | Comment (Nat. Pro.) | Rev. | Reac. |
|---|---|---|---|---|---|---|---|
| 3.4.23.46 | amyloid precursor protein + H2O | Rattus norvegicus | - |
neurotrophic soluble amyloid precursor protein + ? | - |
? | |
Organism
| EC Number | Organism | UniProt | Comment | Textmining |
|---|---|---|---|---|
| 3.4.23.46 | Rattus norvegicus | - |
- |
- |
Substrates and Products (Substrate)
| EC Number | Substrates | Comment Substrates | Organism | Products | Comment (Products) | Rev. | Reac. |
|---|---|---|---|---|---|---|---|
| 3.4.23.46 | amyloid precursor protein + H2O | - |
Rattus norvegicus | neurotrophic soluble amyloid precursor protein + ? | - |
? | |
Synonyms
| EC Number | Synonyms | Comment | Organism |
|---|---|---|---|
| 3.4.23.46 | alpha-secretase | - |
Rattus norvegicus |
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Release 2023.1 (January 2023)
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