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Literature summary extracted from

  • Aguilar-Osorio, G.; Vankuyk, P.A.; Seiboth, B.; Blom, D.; Solomon, P.S.; Vinck, A.; Kindt, F.; Woesten, H.A.; de Vries, R.P.
    Spatial and developmental differentiation of mannitol dehydrogenase and mannitol-1-phosphate dehydrogenase in Aspergillus niger (2010), Eukaryot. Cell, 9, 1398-1402.
    View publication on PubMedView publication on EuropePMC

Cloned(Commentary)

EC Number Cloned (Comment) Organism
1.1.1.17 gene mpdA Aspergillus niger

Natural Substrates/ Products (Substrates)

EC Number Natural Substrates Organism Comment (Nat. Sub.) Natural Products Comment (Nat. Pro.) Rev. Reac.
1.1.1.17 D-mannitol 1-phosphate + NAD+ Aspergillus niger
-
 D-fructose 6-phosphate + NADH + H+
-
 r

Organism

EC Number Organism UniProt Comment Textmining
1.1.1.17 Aspergillus niger
-
 gene mpdA
-

Source Tissue

EC Number Source Tissue Comment Organism Textmining
1.1.1.17 hypha
-
 Aspergillus niger
-
1.1.1.17 additional information poor expression of MpdA in conidiospores, expression anaylsis Aspergillus niger
-

Specific Activity [micromol/min/mg]

EC Number Specific Activity Minimum [µmol/min/mg] Specific Activity Maximum [µmol/min/mg] Comment Organism
1.1.1.17 2.8
-
 premature conidiospores, pH not specified in the publication, temperature not specified in the publication Aspergillus niger
1.1.1.17 18.6
-
 mature conidiospores, pH not specified in the publication, temperature not specified in the publication Aspergillus niger
1.1.1.17 68.3
-
 non-sporulating mycelium, pH not specified in the publication, temperature not specified in the publication Aspergillus niger
1.1.1.17 453.9
-
 sporulating mycelium, pH not specified in the publication, temperature not specified in the publication Aspergillus niger

Substrates and Products (Substrate)

EC Number Substrates Comment Substrates Organism Products Comment (Products) Rev. Reac.
1.1.1.17 D-mannitol 1-phosphate + NAD+
-
 Aspergillus niger D-fructose 6-phosphate + NADH + H+
-
 r

Synonyms

EC Number Synonyms Comment Organism
1.1.1.17 mannitol-1-phosphate dehydrogenase
-
 Aspergillus niger
1.1.1.17 MpdA
-
 Aspergillus niger

Cofactor

EC Number Cofactor Comment Organism Structure
1.1.1.17 NAD+
-
 Aspergillus niger
1.1.1.17 NADH
-
 Aspergillus niger

General Information

EC Number General Information Comment Organism
1.1.1.17 metabolism the enzyme is involved in the mannitol cycle in the fungus Aspergillus niger