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Literature summary extracted from

  • Hu, Z.; Lee, K.S.; Choo, Y.M.; Yoon, H.J.; Lee, S.M.; Lee, J.H.; Kim, D.H.; Sohn, H.D.; Jin, B.R.
    Molecular cloning and characterization of 1-Cys and 2-Cys peroxiredoxins from the bumblebee Bombus ignitus (2010), Comp. Biochem. Physiol. B, 155, 272-280.
    View publication on PubMed

Cloned(Commentary)

EC Number Cloned (Comment) Organism
1.11.1.24 gene BiPrx1, encoding a 1-Cys type Prx, DNA and amino acid sequence determination and analysis, sequence comparison and phylogenetic analysis, determination of the transcriptional expression profile of BiPrx1, expression in Spodoptera frugiperda Sf9 cells using baculovirus transfection system Bombus ignitus
1.11.1.24 gene BiTPx1, encoding a 2-Cys type Prx, DNA and amino acid sequence determination and analysis, sequence comparison and phylogenetic analysis, transcriptional expression profile of BiTPx1, expression in Spodoptera frugiperda Sf9 cells using baculovirus transfection system Bombus ignitus

Protein Variants

EC Number Protein Variants Comment Organism
1.11.1.24 additional information RNAi-induced BiPrx1 knockdown in worker bees causes upregulated expression of BiTPx1. Reciprocally, BiTPx1 RNAi knockdown causes upregulation of BiPrx1 expression in the fat body Bombus ignitus

Molecular Weight [Da]

EC Number Molecular Weight [Da] Molecular Weight Maximum [Da] Comment Organism
1.11.1.24 25000
-
 x * 25000, BiTPx1, SDS-PAGE Bombus ignitus
1.11.1.24 27000
-
 x * 27000, BiPrx1, SDS-PAGE Bombus ignitus

Organism

EC Number Organism UniProt Comment Textmining
1.11.1.24 Bombus ignitus C3VVL4 BiTPrx1; gene BiTPx1 encoding a 2-Cys type Prx
-
1.11.1.24 Bombus ignitus C3VVL6 BiPrx1; gene BiPrx1 encoding a 1-Cys type Prx
-

Source Tissue

EC Number Source Tissue Comment Organism Textmining
1.11.1.24 epidermis
-
 Bombus ignitus
-
1.11.1.24 fat body
-
 Bombus ignitus
-
1.11.1.24 midgut
-
 Bombus ignitus
-
1.11.1.24 additional information not in the hemolymph Bombus ignitus
-
1.11.1.24 muscle
-
 Bombus ignitus
-

Substrates and Products (Substrate)

EC Number Substrates Comment Substrates Organism Products Comment (Products) Rev. Reac.
1.11.1.24 2 thioredoxin + ROOH
-
 Bombus ignitus thioredoxin disulfide + H2O + ROH
-
 ?

Subunits

EC Number Subunits Comment Organism
1.11.1.24 ? x * 25000, BiTPx1, SDS-PAGE Bombus ignitus
1.11.1.24 ? x * 27000, BiPrx1, SDS-PAGE Bombus ignitus

Synonyms

EC Number Synonyms Comment Organism
1.11.1.24 1-Cys type Prx
-
 Bombus ignitus
1.11.1.24 2-Cys type Prx
-
 Bombus ignitus
1.11.1.24 BiPrx1
-
 Bombus ignitus
1.11.1.24 BiTPx1
-
 Bombus ignitus

pH Optimum

EC Number pH Optimum Minimum pH Optimum Maximum Comment Organism
1.11.1.24 7
-
 assay at Bombus ignitus

Expression

EC Number Organism Comment Expression
1.11.1.24 Bombus ignitus RNAi-induced BiPrx1 knockdown in worker bees causes upregulated expression of BiTPx1. Reciprocally, BiTPx1 RNAi knockdown causes upregulation of BiPrx1 expression in the fat body up

General Information

EC Number General Information Comment Organism
1.11.1.24 additional information regulation of BiPrx1 and BiTPx1 expression via reduction of transcript levels in the fat body with RNA interference, overview. RNAi-induced BiPrx1 knockdown in worker bees causes upregulated expression of BiTPx1. Reciprocally, BiTPx1 RNAi knockdown causes upregulation of BiPrx1 expression in the fat body Bombus ignitus