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Literature summary extracted from

  • Blbulyan, S.; Avagyan, A.; Poladyan, A.; Trchounian, A.
    Role of Escherichia coli different hydrogenases in H+ efflux and the FOF1-ATPase activity during glycerol fermentation at different pH (2010), Biosci. Rep., 31, 179-184.
    View publication on PubMed

Inhibitors

EC Number Inhibitors Comment Organism Structure
7.1.2.2 N,N'-dicyclohexylcarbodiimide a nonspecific FOF1-ATPase inhibitor, inhibits ATPase activity and also other membrane mechanisms involved in H+ translocation, in a pH-dependent manner in hya mutants, overview Escherichia coli

Localization

EC Number Localization Comment Organism GeneOntology No. Textmining
7.1.2.2 membrane
-
 Escherichia coli 16020
-

Metals/Ions

EC Number Metals/Ions Comment Organism Structure
7.1.2.2 additional information no stimulation of ATPase activity by K+ Escherichia coli

Natural Substrates/ Products (Substrates)

EC Number Natural Substrates Organism Comment (Nat. Sub.) Natural Products Comment (Nat. Pro.) Rev. Reac.
7.1.2.2 ATP + H2O + H+/in Escherichia coli
-
 ADP + phosphate + H+/out
-
 r
7.1.2.2 ATP + H2O + H+/in Escherichia coli BW25113
-
 ADP + phosphate + H+/out
-
 r

Organism

EC Number Organism UniProt Comment Textmining
7.1.2.2 Escherichia coli
-
-
-
7.1.2.2 Escherichia coli BW25113
-
-
-

Substrates and Products (Substrate)

EC Number Substrates Comment Substrates Organism Products Comment (Products) Rev. Reac.
7.1.2.2 ATP + H2O + H+/in
-
 Escherichia coli ADP + phosphate + H+/out
-
 r
7.1.2.2 ATP + H2O + H+/in
-
 Escherichia coli BW25113 ADP + phosphate + H+/out
-
 r

Synonyms

EC Number Synonyms Comment Organism
7.1.2.2 FoF1-ATPase
-
 Escherichia coli

pH Optimum

EC Number pH Optimum Minimum pH Optimum Maximum Comment Organism
7.1.2.2 7.5
-
 assay at Escherichia coli

pH Range

EC Number pH Minimum pH Maximum Comment Organism
7.1.2.2 5.5 7.5 at pH 7.5 H+ efflux is stimulated in fhlA mutant, with defective transcriptional activator of Hyd-3 or Hyd-4, and lowered in hyaB or hybC mutants, with defective Hyd-1 or Hyd-2. At pH 5.5 H+ efflux in wild-type cells is lowered compared with that at pH 7.5, but is increased in fhlA mutant and absent in hyaB/hybC mutant, overview Escherichia coli