EC Number | Natural Substrates | Organism | Comment (Nat. Sub.) | Natural Products | Comment (Nat. Pro.) | Rev. | Reac. |
---|---|---|---|---|---|---|---|
3.4.23.46 | beta-amyloid precursor protein + H2O | Cricetulus griseus | the loss of Niemann-Pick type C1 increases beta-secretase cleavage of beta-amyloid precursor protein | fragments of amyloid precursor protein | - |
? | |
3.4.23.46 | beta-amyloid precursor protein + H2O | Cricetulus griseus | - |
fragments of beta-amyloid precursor protein | - |
? |
EC Number | Organism | UniProt | Comment | Textmining |
---|---|---|---|---|
3.4.23.46 | Cricetulus griseus | - |
- |
- |
EC Number | Source Tissue | Comment | Organism | Textmining |
---|---|---|---|---|
3.4.23.46 | CHO cell | - |
Cricetulus griseus | - |
EC Number | Substrates | Comment Substrates | Organism | Products | Comment (Products) | Rev. | Reac. |
---|---|---|---|---|---|---|---|
3.4.23.46 | beta-amyloid precursor protein + H2O | the loss of Niemann-Pick type C1 increases beta-secretase cleavage of beta-amyloid precursor protein | Cricetulus griseus | fragments of amyloid precursor protein | - |
? | |
3.4.23.46 | beta-amyloid precursor protein + H2O | - |
Cricetulus griseus | fragments of beta-amyloid precursor protein | - |
? |
EC Number | Synonyms | Comment | Organism |
---|---|---|---|
3.4.23.46 | BACE-1 | - |
Cricetulus griseus |
3.4.23.46 | BACE1 | - |
Cricetulus griseus |
3.4.23.46 | beta-secretase | - |
Cricetulus griseus |
EC Number | Organism | Comment | Expression |
---|---|---|---|
3.4.23.46 | Cricetulus griseus | the loss of Niemann-Pick type C1 affects beta-amyloid generation by increasing beta-secretase cleavage | up |