BRENDA - Enzyme Database

Sodium-translocating NADH:quinone oxidoreductase as a redox-driven ion pump

Verkhovsky, M.I.; Bogachev, A.V.; Biochim. Biophys. Acta 1797, 738-746 (2010)

Data extracted from this reference:

Inhibitors
EC Number
Inhibitors
Commentary
Organism
Structure
7.2.1.1
2-n-heptyl-4-hydroxyquinoline-N-oxide
-
Haemophilus influenzae
7.2.1.1
2-n-heptyl-4-hydroxyquinoline-N-oxide
-
Klebsiella pneumoniae
7.2.1.1
2-n-heptyl-4-hydroxyquinoline-N-oxide
-
Neisseria gonorrhoeae
7.2.1.1
2-n-heptyl-4-hydroxyquinoline-N-oxide
-
Neisseria meningitidis
7.2.1.1
2-n-heptyl-4-hydroxyquinoline-N-oxide
-
Porphyromonas gingivalis
7.2.1.1
2-n-heptyl-4-hydroxyquinoline-N-oxide
-
Pseudomonas aeruginosa
7.2.1.1
2-n-heptyl-4-hydroxyquinoline-N-oxide
-
Vibrio alginolyticus
7.2.1.1
2-n-heptyl-4-hydroxyquinoline-N-oxide
-
Vibrio harveyi
7.2.1.1
2-n-heptyl-4-hydroxyquinoline-N-oxide
-
Yersinia pestis
7.2.1.1
2-n-heptyl-4-hydroxyquinoline-N-oxide
-
Vibrio cholerae
7.2.1.1
Ag+
-
Azotobacter vinelandii
7.2.1.1
Ag+
-
Haemophilus influenzae
7.2.1.1
Ag+
-
Neisseria gonorrhoeae
7.2.1.1
Ag+
-
Neisseria meningitidis
7.2.1.1
Ag+
-
Porphyromonas gingivalis
7.2.1.1
Ag+
-
Pseudomonas aeruginosa
7.2.1.1
Ag+
-
Vibrio cholerae
7.2.1.1
Ag+
-
Vibrio harveyi
7.2.1.1
Ag+
-
Yersinia pestis
7.2.1.1
Ag+
-
Vibrio alginolyticus
7.2.1.1
Cd2+
-
Azotobacter vinelandii
7.2.1.1
Cd2+
-
Haemophilus influenzae
7.2.1.1
Cd2+
-
Klebsiella pneumoniae
7.2.1.1
Cd2+
-
Neisseria gonorrhoeae
7.2.1.1
Cd2+
-
Neisseria meningitidis
7.2.1.1
Cd2+
-
Porphyromonas gingivalis
7.2.1.1
Cd2+
-
Pseudomonas aeruginosa
7.2.1.1
Cd2+
-
Vibrio alginolyticus
7.2.1.1
Cd2+
-
Vibrio cholerae
7.2.1.1
Cd2+
-
Vibrio harveyi
7.2.1.1
Cd2+
-
Yersinia pestis
7.2.1.1
Cu2+
-
Azotobacter vinelandii
7.2.1.1
Cu2+
-
Haemophilus influenzae
7.2.1.1
Cu2+
-
Klebsiella pneumoniae
7.2.1.1
Cu2+
-
Neisseria gonorrhoeae
7.2.1.1
Cu2+
-
Neisseria meningitidis
7.2.1.1
Cu2+
-
Porphyromonas gingivalis
7.2.1.1
Cu2+
-
Pseudomonas aeruginosa
7.2.1.1
Cu2+
-
Vibrio alginolyticus
7.2.1.1
Cu2+
-
Vibrio cholerae
7.2.1.1
Cu2+
-
Vibrio harveyi
7.2.1.1
Cu2+
-
Yersinia pestis
7.2.1.1
korormicin
specifically inhibits Na+-NQR at the level of its interaction with ubiquinone
Azotobacter vinelandii
7.2.1.1
korormicin
specifically inhibits Na+-NQR at the level of its interaction with ubiquinone
Klebsiella pneumoniae
7.2.1.1
korormicin
specifically inhibits Na+-NQR at the level of its interaction with ubiquinone
Neisseria gonorrhoeae
7.2.1.1
korormicin
specifically inhibits Na+-NQR at the level of its interaction with ubiquinone
Neisseria meningitidis
7.2.1.1
korormicin
specifically inhibits Na+-NQR at the level of its interaction with ubiquinone
Porphyromonas gingivalis
7.2.1.1
korormicin
specifically inhibits Na+-NQR at the level of its interaction with ubiquinone
Pseudomonas aeruginosa
7.2.1.1
korormicin
specifically inhibits Na+-NQR at the level of its interaction with ubiquinone
Vibrio alginolyticus
7.2.1.1
korormicin
specifically inhibits Na+-NQR at the level of its interaction with ubiquinone
Vibrio cholerae
7.2.1.1
korormicin
specifically inhibits Na+-NQR at the level of its interaction with ubiquinone
Vibrio harveyi
7.2.1.1
korormicin
specifically inhibits Na+-NQR at the level of its interaction with ubiquinone
Yersinia pestis
7.2.1.1
additional information
Na+-NQR from Azotobacter vinelandii is not sensitive to low 2-n-heptyl-4-hydroxyquinoline-N-oxide concentrations
Azotobacter vinelandii
7.2.1.1
additional information
korormicin has no effect on the enzyme from Haemophilus influenza
Haemophilus influenzae
7.2.1.1
additional information
Na+-NQR from Klebsiella pneumoniae is fully resistant to either Ag+ or N-ethylmaleimide
Klebsiella pneumoniae
7.2.1.1
N-ethylmaleimide
-
Azotobacter vinelandii
7.2.1.1
N-ethylmaleimide
-
Haemophilus influenzae
7.2.1.1
N-ethylmaleimide
-
Neisseria gonorrhoeae
7.2.1.1
N-ethylmaleimide
-
Neisseria meningitidis
7.2.1.1
N-ethylmaleimide
-
Porphyromonas gingivalis
7.2.1.1
N-ethylmaleimide
-
Pseudomonas aeruginosa
7.2.1.1
N-ethylmaleimide
-
Vibrio alginolyticus
7.2.1.1
N-ethylmaleimide
-
Vibrio cholerae
7.2.1.1
N-ethylmaleimide
-
Vibrio harveyi
7.2.1.1
N-ethylmaleimide
-
Yersinia pestis
7.2.1.1
Pb2+
-
Azotobacter vinelandii
7.2.1.1
Pb2+
-
Haemophilus influenzae
7.2.1.1
Pb2+
-
Klebsiella pneumoniae
7.2.1.1
Pb2+
-
Neisseria gonorrhoeae
7.2.1.1
Pb2+
-
Neisseria meningitidis
7.2.1.1
Pb2+
-
Porphyromonas gingivalis
7.2.1.1
Pb2+
-
Pseudomonas aeruginosa
7.2.1.1
Pb2+
-
Vibrio alginolyticus
7.2.1.1
Pb2+
-
Vibrio cholerae
7.2.1.1
Pb2+
-
Yersinia pestis
7.2.1.1
Pb2+
-
Vibrio harveyi
7.2.1.1
Zn2+
-
Azotobacter vinelandii
7.2.1.1
Zn2+
-
Haemophilus influenzae
7.2.1.1
Zn2+
-
Klebsiella pneumoniae
7.2.1.1
Zn2+
-
Neisseria gonorrhoeae
7.2.1.1
Zn2+
-
Neisseria meningitidis
7.2.1.1
Zn2+
-
Porphyromonas gingivalis
7.2.1.1
Zn2+
-
Pseudomonas aeruginosa
7.2.1.1
Zn2+
-
Vibrio alginolyticus
7.2.1.1
Zn2+
-
Vibrio cholerae
7.2.1.1
Zn2+
-
Vibrio harveyi
7.2.1.1
Zn2+
-
Yersinia pestis
Metals/Ions
EC Number
Metals/Ions
Commentary
Organism
Structure
7.2.1.1
Na+
specific requirement for sodium ions, even in the absence of sodium ions Na+-NQR is unable to translocate protons
Azotobacter vinelandii
7.2.1.1
Na+
specific requirement for sodium ions, even in the absence of sodium ions Na+-NQR is unable to translocate protons
Haemophilus influenzae
7.2.1.1
Na+
specific requirement for sodium ions, even in the absence of sodium ions Na+-NQR is unable to translocate protons
Klebsiella pneumoniae
7.2.1.1
Na+
specific requirement for sodium ions, even in the absence of sodium ions Na+-NQR is unable to translocate protons
Neisseria gonorrhoeae
7.2.1.1
Na+
specific requirement for sodium ions, even in the absence of sodium ions Na+-NQR is unable to translocate protons
Neisseria meningitidis
7.2.1.1
Na+
specific requirement for sodium ions, even in the absence of sodium ions Na+-NQR is unable to translocate protons
Porphyromonas gingivalis
7.2.1.1
Na+
specific requirement for sodium ions, even in the absence of sodium ions Na+-NQR is unable to translocate protons
Pseudomonas aeruginosa
7.2.1.1
Na+
specific requirement for sodium ions, even in the absence of sodium ions Na+-NQR is unable to translocate protons
Vibrio alginolyticus
7.2.1.1
Na+
specific requirement for sodium ions, even in the absence of sodium ions Na+-NQR is unable to translocate protons
Vibrio cholerae
7.2.1.1
Na+
specific requirement for sodium ions, even in the absence of sodium ions Na+-NQR is unable to translocate protons
Vibrio harveyi
7.2.1.1
Na+
specific requirement for sodium ions, even in the absence of sodium ions Na+-NQR is unable to translocate protons
Yersinia pestis
Molecular Weight [Da]
EC Number
Molecular Weight [Da]
Molecular Weight Maximum [Da]
Commentary
Organism
7.2.1.1
21500
-
1 * 48400 + 1 * 45400 + 1 * 27500 + 1 * 22700 + 1 * 21500 + 1 * 45200, calculated from amino acid sequence
Vibrio harveyi
7.2.1.1
22700
-
1 * 48400 + 1 * 45400 + 1 * 27500 + 1 * 22700 + 1 * 21500 + 1 * 45200, calculated from amino acid sequence
Vibrio harveyi
7.2.1.1
27500
-
1 * 48400 + 1 * 45400 + 1 * 27500 + 1 * 22700 + 1 * 21500 + 1 * 45200, calculated from amino acid sequence
Vibrio harveyi
7.2.1.1
45200
-
1 * 48400 + 1 * 45400 + 1 * 27500 + 1 * 22700 + 1 * 21500 + 1 * 45200, calculated from amino acid sequence
Vibrio harveyi
7.2.1.1
45400
-
1 * 48400 + 1 * 45400 + 1 * 27500 + 1 * 22700 + 1 * 21500 + 1 * 45200, calculated from amino acid sequence
Vibrio harveyi
7.2.1.1
48400
-
1 * 48400 + 1 * 45400 + 1 * 27500 + 1 * 22700 + 1 * 21500 + 1 * 45200, calculated from amino acid sequence
Vibrio harveyi
Natural Substrates/ Products (Substrates)
EC Number
Natural Substrates
Organism
Commentary (Nat. Sub.)
Natural Products
Commentary (Nat. Pro.)
Organism (Nat. Pro.)
Reversibility
7.2.1.1
deamino-NADH + H+ + ubiquinone + 2 Na+/in
Haemophilus influenzae
-
deamino-NAD+ + ubiquinol + 2 Na+/out
-
-
?
7.2.1.1
deamino-NADH + H+ + ubiquinone + 2 Na+/in
Vibrio harveyi
-
deamino-NAD+ + ubiquinol + 2 Na+/out
-
-
?
7.2.1.1
deamino-NADH + H+ + ubiquinone + 2 Na+/in
Pseudomonas aeruginosa
-
deamino-NAD+ + ubiquinol + 2 Na+/out
-
-
?
7.2.1.1
deamino-NADH + H+ + ubiquinone + 2 Na+/in
Neisseria gonorrhoeae
-
deamino-NAD+ + ubiquinol + 2 Na+/out
-
-
?
7.2.1.1
deamino-NADH + H+ + ubiquinone + 2 Na+/in
Neisseria meningitidis
-
deamino-NAD+ + ubiquinol + 2 Na+/out
-
-
?
7.2.1.1
deamino-NADH + H+ + ubiquinone + 2 Na+/in
Klebsiella pneumoniae
-
deamino-NAD+ + ubiquinol + 2 Na+/out
-
-
?
7.2.1.1
deamino-NADH + H+ + ubiquinone + 2 Na+/in
Azotobacter vinelandii
-
deamino-NAD+ + ubiquinol + 2 Na+/out
-
-
?
7.2.1.1
deamino-NADH + H+ + ubiquinone + 2 Na+/in
Yersinia pestis
-
deamino-NAD+ + ubiquinol + 2 Na+/out
-
-
?
7.2.1.1
deamino-NADH + H+ + ubiquinone + 2 Na+/in
Porphyromonas gingivalis
-
deamino-NAD+ + ubiquinol + 2 Na+/out
-
-
?
7.2.1.1
deamino-NADH + H+ + ubiquinone + 2 Na+/in
Vibrio cholerae
-
deamino-NAD+ + ubiquinol + 2 Na+/out
-
-
?
7.2.1.1
deamino-NADH + H+ + ubiquinone + 2 Na+/in
Vibrio alginolyticus
-
deamino-NAD+ + ubiquinol + 2 Na+/out
-
-
?
7.2.1.1
additional information
Haemophilus influenzae
in addition to the quinone reductase reaction, the isolated enzyme can also catalyze the so-called NADH-dehydrogenase reaction during interaction with soluble quinones. This activity includes a single-electron reduction of soluble quinones (menadione, Q0, Q1, etc.) or some other electron acceptors (hexaammineruthenium (III), ferricyanide, etc.)
?
-
-
-
7.2.1.1
additional information
Vibrio harveyi
in addition to the quinone reductase reaction, the isolated enzyme can also catalyze the so-called NADH-dehydrogenase reaction during interaction with soluble quinones. This activity includes a single-electron reduction of soluble quinones (menadione, Q0, Q1, etc.) or some other electron acceptors (hexaammineruthenium (III), ferricyanide, etc.)
?
-
-
-
7.2.1.1
additional information
Pseudomonas aeruginosa
in addition to the quinone reductase reaction, the isolated enzyme can also catalyze the so-called NADH-dehydrogenase reaction during interaction with soluble quinones. This activity includes a single-electron reduction of soluble quinones (menadione, Q0, Q1, etc.) or some other electron acceptors (hexaammineruthenium (III), ferricyanide, etc.)
?
-
-
-
7.2.1.1
additional information
Neisseria gonorrhoeae
in addition to the quinone reductase reaction, the isolated enzyme can also catalyze the so-called NADH-dehydrogenase reaction during interaction with soluble quinones. This activity includes a single-electron reduction of soluble quinones (menadione, Q0, Q1, etc.) or some other electron acceptors (hexaammineruthenium (III), ferricyanide, etc.)
?
-
-
-
7.2.1.1
additional information
Neisseria meningitidis
in addition to the quinone reductase reaction, the isolated enzyme can also catalyze the so-called NADH-dehydrogenase reaction during interaction with soluble quinones. This activity includes a single-electron reduction of soluble quinones (menadione, Q0, Q1, etc.) or some other electron acceptors (hexaammineruthenium (III), ferricyanide, etc.)
?
-
-
-
7.2.1.1
additional information
Klebsiella pneumoniae
in addition to the quinone reductase reaction, the isolated enzyme can also catalyze the so-called NADH-dehydrogenase reaction during interaction with soluble quinones. This activity includes a single-electron reduction of soluble quinones (menadione, Q0, Q1, etc.) or some other electron acceptors (hexaammineruthenium (III), ferricyanide, etc.)
?
-
-
-
7.2.1.1
additional information
Azotobacter vinelandii
in addition to the quinone reductase reaction, the isolated enzyme can also catalyze the so-called NADH-dehydrogenase reaction during interaction with soluble quinones. This activity includes a single-electron reduction of soluble quinones (menadione, Q0, Q1, etc.) or some other electron acceptors (hexaammineruthenium (III), ferricyanide, etc.)
?
-
-
-
7.2.1.1
additional information
Yersinia pestis
in addition to the quinone reductase reaction, the isolated enzyme can also catalyze the so-called NADH-dehydrogenase reaction during interaction with soluble quinones. This activity includes a single-electron reduction of soluble quinones (menadione, Q0, Q1, etc.) or some other electron acceptors (hexaammineruthenium (III), ferricyanide, etc.)
?
-
-
-
7.2.1.1
additional information
Porphyromonas gingivalis
in addition to the quinone reductase reaction, the isolated enzyme can also catalyze the so-called NADH-dehydrogenase reaction during interaction with soluble quinones. This activity includes a single-electron reduction of soluble quinones (menadione, Q0, Q1, etc.) or some other electron acceptors (hexaammineruthenium (III), ferricyanide, etc.)
?
-
-
-
7.2.1.1
additional information
Vibrio cholerae
in addition to the quinone reductase reaction, the isolated enzyme can also catalyze the so-called NADH-dehydrogenase reaction during interaction with soluble quinones. This activity includes a single-electron reduction of soluble quinones (menadione, Q0, Q1, etc.) or some other electron acceptors (hexaammineruthenium (III), ferricyanide, etc.)
?
-
-
-
7.2.1.1
additional information
Vibrio alginolyticus
in addition to the quinone reductase reaction, the isolated enzyme can also catalyze the so-called NADH-dehydrogenase reaction during interaction with soluble quinones. This activity includes a single-electron reduction of soluble quinones (menadione, Q0, Q1, etc.) or some other electron acceptors (hexaammineruthenium (III), ferricyanide, etc.)
?
-
-
-
7.2.1.1
additional information
Haemophilus influenzae
Na+-NQR does not oxidize NADPH
?
-
-
-
7.2.1.1
additional information
Vibrio harveyi
Na+-NQR does not oxidize NADPH
?
-
-
-
7.2.1.1
additional information
Pseudomonas aeruginosa
Na+-NQR does not oxidize NADPH
?
-
-
-
7.2.1.1
additional information
Neisseria gonorrhoeae
Na+-NQR does not oxidize NADPH
?
-
-
-
7.2.1.1
additional information
Neisseria meningitidis
Na+-NQR does not oxidize NADPH
?
-
-
-
7.2.1.1
additional information
Klebsiella pneumoniae
Na+-NQR does not oxidize NADPH
?
-
-
-
7.2.1.1
additional information
Azotobacter vinelandii
Na+-NQR does not oxidize NADPH
?
-
-
-
7.2.1.1
additional information
Yersinia pestis
Na+-NQR does not oxidize NADPH
?
-
-
-
7.2.1.1
additional information
Porphyromonas gingivalis
Na+-NQR does not oxidize NADPH
?
-
-
-
7.2.1.1
additional information
Vibrio cholerae
Na+-NQR does not oxidize NADPH
?
-
-
-
7.2.1.1
additional information
Vibrio alginolyticus
Na+-NQR does not oxidize NADPH
?
-
-
-
7.2.1.1
NADH + H+ + ubiquinone + 2 Na+/in
Haemophilus influenzae
-
NAD+ + ubiquinol + 2 Na+/out
-
-
?
7.2.1.1
NADH + H+ + ubiquinone + 2 Na+/in
Vibrio harveyi
-
NAD+ + ubiquinol + 2 Na+/out
-
-
?
7.2.1.1
NADH + H+ + ubiquinone + 2 Na+/in
Pseudomonas aeruginosa
-
NAD+ + ubiquinol + 2 Na+/out
-
-
?
7.2.1.1
NADH + H+ + ubiquinone + 2 Na+/in
Neisseria gonorrhoeae
-
NAD+ + ubiquinol + 2 Na+/out
-
-
?
7.2.1.1
NADH + H+ + ubiquinone + 2 Na+/in
Neisseria meningitidis
-
NAD+ + ubiquinol + 2 Na+/out
-
-
?
7.2.1.1
NADH + H+ + ubiquinone + 2 Na+/in
Klebsiella pneumoniae
-
NAD+ + ubiquinol + 2 Na+/out
-
-
?
7.2.1.1
NADH + H+ + ubiquinone + 2 Na+/in
Azotobacter vinelandii
-
NAD+ + ubiquinol + 2 Na+/out
-
-
?
7.2.1.1
NADH + H+ + ubiquinone + 2 Na+/in
Yersinia pestis
-
NAD+ + ubiquinol + 2 Na+/out
-
-
?
7.2.1.1
NADH + H+ + ubiquinone + 2 Na+/in
Porphyromonas gingivalis
-
NAD+ + ubiquinol + 2 Na+/out
-
-
?
7.2.1.1
NADH + H+ + ubiquinone + 2 Na+/in
Vibrio cholerae
-
NAD+ + ubiquinol + 2 Na+/out
-
-
?
7.2.1.1
NADH + H+ + ubiquinone + 2 Na+/in
Vibrio alginolyticus
-
NAD+ + ubiquinol + 2 Na+/out
-
-
?
7.2.1.1
thio-NADH + H+ + ubiquinone + 2 Na+/in
Haemophilus influenzae
-
thio-NAD+ + ubiquinol + 2 Na+/out
-
-
?
7.2.1.1
thio-NADH + H+ + ubiquinone + 2 Na+/in
Vibrio harveyi
-
thio-NAD+ + ubiquinol + 2 Na+/out
-
-
?
7.2.1.1
thio-NADH + H+ + ubiquinone + 2 Na+/in
Pseudomonas aeruginosa
-
thio-NAD+ + ubiquinol + 2 Na+/out
-
-
?
7.2.1.1
thio-NADH + H+ + ubiquinone + 2 Na+/in
Neisseria gonorrhoeae
-
thio-NAD+ + ubiquinol + 2 Na+/out
-
-
?
7.2.1.1
thio-NADH + H+ + ubiquinone + 2 Na+/in
Neisseria meningitidis
-
thio-NAD+ + ubiquinol + 2 Na+/out
-
-
?
7.2.1.1
thio-NADH + H+ + ubiquinone + 2 Na+/in
Klebsiella pneumoniae
-
thio-NAD+ + ubiquinol + 2 Na+/out
-
-
?
7.2.1.1
thio-NADH + H+ + ubiquinone + 2 Na+/in
Azotobacter vinelandii
-
thio-NAD+ + ubiquinol + 2 Na+/out
-
-
?
7.2.1.1
thio-NADH + H+ + ubiquinone + 2 Na+/in
Yersinia pestis
-
thio-NAD+ + ubiquinol + 2 Na+/out
-
-
?
7.2.1.1
thio-NADH + H+ + ubiquinone + 2 Na+/in
Porphyromonas gingivalis
-
thio-NAD+ + ubiquinol + 2 Na+/out
-
-
?
7.2.1.1
thio-NADH + H+ + ubiquinone + 2 Na+/in
Vibrio cholerae
-
thio-NAD+ + ubiquinol + 2 Na+/out
-
-
?
7.2.1.1
thio-NADH + H+ + ubiquinone + 2 Na+/in
Vibrio alginolyticus
-
thio-NAD+ + ubiquinol + 2 Na+/out
-
-
?
Organism
EC Number
Organism
Primary Accession No. (UniProt)
Commentary
Textmining
7.2.1.1
Azotobacter vinelandii
-
-
-
7.2.1.1
Haemophilus influenzae
-
-
-
7.2.1.1
Klebsiella pneumoniae
-
-
-
7.2.1.1
Neisseria gonorrhoeae
-
-
-
7.2.1.1
Neisseria meningitidis
-
-
-
7.2.1.1
Porphyromonas gingivalis
-
-
-
7.2.1.1
Pseudomonas aeruginosa
-
-
-
7.2.1.1
Vibrio alginolyticus
-
-
-
7.2.1.1
Vibrio cholerae
-
-
-
7.2.1.1
Vibrio harveyi
-
-
-
7.2.1.1
Yersinia pestis
-
-
-
Substrates and Products (Substrate)
EC Number
Substrates
Commentary Substrates
Literature (Substrates)
Organism
Products
Commentary (Products)
Literature (Products)
Organism (Products)
Reversibility
7.2.1.1
deamino-NADH + H+ + ubiquinone + 2 Na+/in
-
711293
Haemophilus influenzae
deamino-NAD+ + ubiquinol + 2 Na+/out
-
-
-
?
7.2.1.1
deamino-NADH + H+ + ubiquinone + 2 Na+/in
-
711293
Vibrio harveyi
deamino-NAD+ + ubiquinol + 2 Na+/out
-
-
-
?
7.2.1.1
deamino-NADH + H+ + ubiquinone + 2 Na+/in
-
711293
Pseudomonas aeruginosa
deamino-NAD+ + ubiquinol + 2 Na+/out
-
-
-
?
7.2.1.1
deamino-NADH + H+ + ubiquinone + 2 Na+/in
-
711293
Neisseria gonorrhoeae
deamino-NAD+ + ubiquinol + 2 Na+/out
-
-
-
?
7.2.1.1
deamino-NADH + H+ + ubiquinone + 2 Na+/in
-
711293
Neisseria meningitidis
deamino-NAD+ + ubiquinol + 2 Na+/out
-
-
-
?
7.2.1.1
deamino-NADH + H+ + ubiquinone + 2 Na+/in
-
711293
Klebsiella pneumoniae
deamino-NAD+ + ubiquinol + 2 Na+/out
-
-
-
?
7.2.1.1
deamino-NADH + H+ + ubiquinone + 2 Na+/in
-
711293
Azotobacter vinelandii
deamino-NAD+ + ubiquinol + 2 Na+/out
-
-
-
?
7.2.1.1
deamino-NADH + H+ + ubiquinone + 2 Na+/in
-
711293
Yersinia pestis
deamino-NAD+ + ubiquinol + 2 Na+/out
-
-
-
?
7.2.1.1
deamino-NADH + H+ + ubiquinone + 2 Na+/in
-
711293
Porphyromonas gingivalis
deamino-NAD+ + ubiquinol + 2 Na+/out
-
-
-
?
7.2.1.1
deamino-NADH + H+ + ubiquinone + 2 Na+/in
-
711293
Vibrio cholerae
deamino-NAD+ + ubiquinol + 2 Na+/out
-
-
-
?
7.2.1.1
deamino-NADH + H+ + ubiquinone + 2 Na+/in
-
711293
Vibrio alginolyticus
deamino-NAD+ + ubiquinol + 2 Na+/out
-
-
-
?
7.2.1.1
additional information
in addition to the quinone reductase reaction, the isolated enzyme can also catalyze the so-called NADH-dehydrogenase reaction during interaction with soluble quinones. This activity includes a single-electron reduction of soluble quinones (menadione, Q0, Q1, etc.) or some other electron acceptors (hexaammineruthenium (III), ferricyanide, etc.)
711293
Haemophilus influenzae
?
-
-
-
-
7.2.1.1
additional information
in addition to the quinone reductase reaction, the isolated enzyme can also catalyze the so-called NADH-dehydrogenase reaction during interaction with soluble quinones. This activity includes a single-electron reduction of soluble quinones (menadione, Q0, Q1, etc.) or some other electron acceptors (hexaammineruthenium (III), ferricyanide, etc.)
711293
Vibrio harveyi
?
-
-
-
-
7.2.1.1
additional information
in addition to the quinone reductase reaction, the isolated enzyme can also catalyze the so-called NADH-dehydrogenase reaction during interaction with soluble quinones. This activity includes a single-electron reduction of soluble quinones (menadione, Q0, Q1, etc.) or some other electron acceptors (hexaammineruthenium (III), ferricyanide, etc.)
711293
Pseudomonas aeruginosa
?
-
-
-
-
7.2.1.1
additional information
in addition to the quinone reductase reaction, the isolated enzyme can also catalyze the so-called NADH-dehydrogenase reaction during interaction with soluble quinones. This activity includes a single-electron reduction of soluble quinones (menadione, Q0, Q1, etc.) or some other electron acceptors (hexaammineruthenium (III), ferricyanide, etc.)
711293
Neisseria gonorrhoeae
?
-
-
-
-
7.2.1.1
additional information
in addition to the quinone reductase reaction, the isolated enzyme can also catalyze the so-called NADH-dehydrogenase reaction during interaction with soluble quinones. This activity includes a single-electron reduction of soluble quinones (menadione, Q0, Q1, etc.) or some other electron acceptors (hexaammineruthenium (III), ferricyanide, etc.)
711293
Neisseria meningitidis
?
-
-
-
-
7.2.1.1
additional information
in addition to the quinone reductase reaction, the isolated enzyme can also catalyze the so-called NADH-dehydrogenase reaction during interaction with soluble quinones. This activity includes a single-electron reduction of soluble quinones (menadione, Q0, Q1, etc.) or some other electron acceptors (hexaammineruthenium (III), ferricyanide, etc.)
711293
Klebsiella pneumoniae
?
-
-
-
-
7.2.1.1
additional information
in addition to the quinone reductase reaction, the isolated enzyme can also catalyze the so-called NADH-dehydrogenase reaction during interaction with soluble quinones. This activity includes a single-electron reduction of soluble quinones (menadione, Q0, Q1, etc.) or some other electron acceptors (hexaammineruthenium (III), ferricyanide, etc.)
711293
Azotobacter vinelandii
?
-
-
-
-
7.2.1.1
additional information
in addition to the quinone reductase reaction, the isolated enzyme can also catalyze the so-called NADH-dehydrogenase reaction during interaction with soluble quinones. This activity includes a single-electron reduction of soluble quinones (menadione, Q0, Q1, etc.) or some other electron acceptors (hexaammineruthenium (III), ferricyanide, etc.)
711293
Yersinia pestis
?
-
-
-
-
7.2.1.1
additional information
in addition to the quinone reductase reaction, the isolated enzyme can also catalyze the so-called NADH-dehydrogenase reaction during interaction with soluble quinones. This activity includes a single-electron reduction of soluble quinones (menadione, Q0, Q1, etc.) or some other electron acceptors (hexaammineruthenium (III), ferricyanide, etc.)
711293
Porphyromonas gingivalis
?
-
-
-
-
7.2.1.1
additional information
in addition to the quinone reductase reaction, the isolated enzyme can also catalyze the so-called NADH-dehydrogenase reaction during interaction with soluble quinones. This activity includes a single-electron reduction of soluble quinones (menadione, Q0, Q1, etc.) or some other electron acceptors (hexaammineruthenium (III), ferricyanide, etc.)
711293
Vibrio cholerae
?
-
-
-
-
7.2.1.1
additional information
in addition to the quinone reductase reaction, the isolated enzyme can also catalyze the so-called NADH-dehydrogenase reaction during interaction with soluble quinones. This activity includes a single-electron reduction of soluble quinones (menadione, Q0, Q1, etc.) or some other electron acceptors (hexaammineruthenium (III), ferricyanide, etc.)
711293
Vibrio alginolyticus
?
-
-
-
-
7.2.1.1
additional information
Na+-NQR does not oxidize NADPH
711293
Haemophilus influenzae
?
-
-
-
-
7.2.1.1
additional information
Na+-NQR does not oxidize NADPH
711293
Vibrio harveyi
?
-
-
-
-
7.2.1.1
additional information
Na+-NQR does not oxidize NADPH
711293
Pseudomonas aeruginosa
?
-
-
-
-
7.2.1.1
additional information
Na+-NQR does not oxidize NADPH
711293
Neisseria gonorrhoeae
?
-
-
-
-
7.2.1.1
additional information
Na+-NQR does not oxidize NADPH
711293
Neisseria meningitidis
?
-
-
-
-
7.2.1.1
additional information
Na+-NQR does not oxidize NADPH
711293
Klebsiella pneumoniae
?
-
-
-
-
7.2.1.1
additional information
Na+-NQR does not oxidize NADPH
711293
Azotobacter vinelandii
?
-
-
-
-
7.2.1.1
additional information
Na+-NQR does not oxidize NADPH
711293
Yersinia pestis
?
-
-
-
-
7.2.1.1
additional information
Na+-NQR does not oxidize NADPH
711293
Porphyromonas gingivalis
?
-
-
-
-
7.2.1.1
additional information
Na+-NQR does not oxidize NADPH
711293
Vibrio cholerae
?
-
-
-
-
7.2.1.1
additional information
Na+-NQR does not oxidize NADPH
711293
Vibrio alginolyticus
?
-
-
-
-
7.2.1.1
NADH + H+ + ubiquinone + 2 Na+/in
-
711293
Haemophilus influenzae
NAD+ + ubiquinol + 2 Na+/out
-
-
-
?
7.2.1.1
NADH + H+ + ubiquinone + 2 Na+/in
-
711293
Vibrio harveyi
NAD+ + ubiquinol + 2 Na+/out
-
-
-
?
7.2.1.1
NADH + H+ + ubiquinone + 2 Na+/in
-
711293
Pseudomonas aeruginosa
NAD+ + ubiquinol + 2 Na+/out
-
-
-
?
7.2.1.1
NADH + H+ + ubiquinone + 2 Na+/in
-
711293
Neisseria gonorrhoeae
NAD+ + ubiquinol + 2 Na+/out
-
-
-
?
7.2.1.1
NADH + H+ + ubiquinone + 2 Na+/in
-
711293
Neisseria meningitidis
NAD+ + ubiquinol + 2 Na+/out
-
-
-
?
7.2.1.1
NADH + H+ + ubiquinone + 2 Na+/in
-
711293
Klebsiella pneumoniae
NAD+ + ubiquinol + 2 Na+/out
-
-
-
?
7.2.1.1
NADH + H+ + ubiquinone + 2 Na+/in
-
711293
Azotobacter vinelandii
NAD+ + ubiquinol + 2 Na+/out
-
-
-
?
7.2.1.1
NADH + H+ + ubiquinone + 2 Na+/in
-
711293
Yersinia pestis
NAD+ + ubiquinol + 2 Na+/out
-
-
-
?
7.2.1.1
NADH + H+ + ubiquinone + 2 Na+/in
-
711293
Porphyromonas gingivalis
NAD+ + ubiquinol + 2 Na+/out
-
-
-
?
7.2.1.1
NADH + H+ + ubiquinone + 2 Na+/in
-
711293
Vibrio cholerae
NAD+ + ubiquinol + 2 Na+/out
-
-
-
?
7.2.1.1
NADH + H+ + ubiquinone + 2 Na+/in
-
711293
Vibrio alginolyticus
NAD+ + ubiquinol + 2 Na+/out
-
-
-
?
7.2.1.1
thio-NADH + H+ + ubiquinone + 2 Na+/in
-
711293
Haemophilus influenzae
thio-NAD+ + ubiquinol + 2 Na+/out
-
-
-
?
7.2.1.1
thio-NADH + H+ + ubiquinone + 2 Na+/in
-
711293
Vibrio harveyi
thio-NAD+ + ubiquinol + 2 Na+/out
-
-
-
?
7.2.1.1
thio-NADH + H+ + ubiquinone + 2 Na+/in
-
711293
Pseudomonas aeruginosa
thio-NAD+ + ubiquinol + 2 Na+/out
-
-
-
?
7.2.1.1
thio-NADH + H+ + ubiquinone + 2 Na+/in
-
711293
Neisseria gonorrhoeae
thio-NAD+ + ubiquinol + 2 Na+/out
-
-
-
?
7.2.1.1
thio-NADH + H+ + ubiquinone + 2 Na+/in
-
711293
Neisseria meningitidis
thio-NAD+ + ubiquinol + 2 Na+/out
-
-
-
?
7.2.1.1
thio-NADH + H+ + ubiquinone + 2 Na+/in
-
711293
Klebsiella pneumoniae
thio-NAD+ + ubiquinol + 2 Na+/out
-
-
-
?
7.2.1.1
thio-NADH + H+ + ubiquinone + 2 Na+/in
-
711293
Azotobacter vinelandii
thio-NAD+ + ubiquinol + 2 Na+/out
-
-
-
?
7.2.1.1
thio-NADH + H+ + ubiquinone + 2 Na+/in
-
711293
Yersinia pestis
thio-NAD+ + ubiquinol + 2 Na+/out
-
-
-
?
7.2.1.1
thio-NADH + H+ + ubiquinone + 2 Na+/in
-
711293
Porphyromonas gingivalis
thio-NAD+ + ubiquinol + 2 Na+/out
-
-
-
?
7.2.1.1
thio-NADH + H+ + ubiquinone + 2 Na+/in
-
711293
Vibrio cholerae
thio-NAD+ + ubiquinol + 2 Na+/out
-
-
-
?
7.2.1.1
thio-NADH + H+ + ubiquinone + 2 Na+/in
-
711293
Vibrio alginolyticus
thio-NAD+ + ubiquinol + 2 Na+/out
-
-
-
?
Subunits
EC Number
Subunits
Commentary
Organism
7.2.1.1
heterohexamer
1 * 48400 + 1 * 45400 + 1 * 27500 + 1 * 22700 + 1 * 21500 + 1 * 45200, calculated from amino acid sequence
Vibrio harveyi
Cofactor
EC Number
Cofactor
Commentary
Organism
Structure
7.2.1.1
FAD
noncovalently bound to the NqrF subunit of Na+-NQR
Azotobacter vinelandii
7.2.1.1
FAD
noncovalently bound to the NqrF subunit of Na+-NQR
Haemophilus influenzae
7.2.1.1
FAD
noncovalently bound to the NqrF subunit of Na+-NQR
Klebsiella pneumoniae
7.2.1.1
FAD
noncovalently bound to the NqrF subunit of Na+-NQR
Neisseria gonorrhoeae
7.2.1.1
FAD
noncovalently bound to the NqrF subunit of Na+-NQR
Neisseria meningitidis
7.2.1.1
FAD
noncovalently bound to the NqrF subunit of Na+-NQR
Porphyromonas gingivalis
7.2.1.1
FAD
noncovalently bound to the NqrF subunit of Na+-NQR
Pseudomonas aeruginosa
7.2.1.1
FAD
noncovalently bound to the NqrF subunit of Na+-NQR
Vibrio alginolyticus
7.2.1.1
FAD
noncovalently bound to the NqrF subunit of Na+-NQR
Vibrio cholerae
7.2.1.1
FAD
noncovalently bound to the NqrF subunit of Na+-NQR
Vibrio harveyi
7.2.1.1
FAD
noncovalently bound to the NqrF subunit of Na+-NQR
Yersinia pestis
7.2.1.1
FMN
covalently bound to the NqrB and NqrC subunits of Na+-NQR
Azotobacter vinelandii
7.2.1.1
FMN
covalently bound to the NqrB and NqrC subunits of Na+-NQR
Haemophilus influenzae
7.2.1.1
FMN
covalently bound to the NqrB and NqrC subunits of Na+-NQR
Klebsiella pneumoniae
7.2.1.1
FMN
covalently bound to the NqrB and NqrC subunits of Na+-NQR
Neisseria gonorrhoeae
7.2.1.1
FMN
covalently bound to the NqrB and NqrC subunits of Na+-NQR
Neisseria meningitidis
7.2.1.1
FMN
covalently bound to the NqrB and NqrC subunits of Na+-NQR
Porphyromonas gingivalis
7.2.1.1
FMN
covalently bound to the NqrB and NqrC subunits of Na+-NQR
Pseudomonas aeruginosa
7.2.1.1
FMN
covalently bound to the NqrB and NqrC subunits of Na+-NQR
Vibrio alginolyticus
7.2.1.1
FMN
covalently bound to the NqrB and NqrC subunits of Na+-NQR
Vibrio cholerae
7.2.1.1
FMN
covalently bound to the NqrB and NqrC subunits of Na+-NQR
Vibrio harveyi
7.2.1.1
FMN
covalently bound to the NqrB and NqrC subunits of Na+-NQR
Yersinia pestis
7.2.1.1
NADH
Na+-NQR is specific to NADH
Azotobacter vinelandii
7.2.1.1
NADH
Na+-NQR is specific to NADH
Haemophilus influenzae
7.2.1.1
NADH
Na+-NQR is specific to NADH
Klebsiella pneumoniae
7.2.1.1
NADH
Na+-NQR is specific to NADH
Neisseria gonorrhoeae
7.2.1.1
NADH
Na+-NQR is specific to NADH
Neisseria meningitidis
7.2.1.1
NADH
Na+-NQR is specific to NADH
Porphyromonas gingivalis
7.2.1.1
NADH
Na+-NQR is specific to NADH
Pseudomonas aeruginosa
7.2.1.1
NADH
Na+-NQR is specific to NADH
Vibrio alginolyticus
7.2.1.1
NADH
Na+-NQR is specific to NADH
Vibrio cholerae
7.2.1.1
NADH
Na+-NQR is specific to NADH
Vibrio harveyi
7.2.1.1
NADH
Na+-NQR is specific to NADH
Yersinia pestis
7.2.1.1
riboflavin
the enzyme contains one noncovalently bound riboflavin
Azotobacter vinelandii
7.2.1.1
riboflavin
the enzyme contains one noncovalently bound riboflavin
Haemophilus influenzae
7.2.1.1
riboflavin
the enzyme contains one noncovalently bound riboflavin
Klebsiella pneumoniae
7.2.1.1
riboflavin
the enzyme contains one noncovalently bound riboflavin
Neisseria gonorrhoeae
7.2.1.1
riboflavin
the enzyme contains one noncovalently bound riboflavin
Neisseria meningitidis
7.2.1.1
riboflavin
the enzyme contains one noncovalently bound riboflavin
Porphyromonas gingivalis
7.2.1.1
riboflavin
the enzyme contains one noncovalently bound riboflavin
Pseudomonas aeruginosa
7.2.1.1
riboflavin
the enzyme contains one noncovalently bound riboflavin
Vibrio alginolyticus
7.2.1.1
riboflavin
the enzyme contains one noncovalently bound riboflavin
Vibrio cholerae
7.2.1.1
riboflavin
the enzyme contains one noncovalently bound riboflavin
Vibrio harveyi
7.2.1.1
riboflavin
the enzyme contains one noncovalently bound riboflavin
Yersinia pestis
7.2.1.1
ubiquinone-8
the enzyme contains one ubiquinone-8
Azotobacter vinelandii
7.2.1.1
ubiquinone-8
the enzyme contains one ubiquinone-8
Haemophilus influenzae
7.2.1.1
ubiquinone-8
the enzyme contains one ubiquinone-8
Klebsiella pneumoniae
7.2.1.1
ubiquinone-8
the enzyme contains one ubiquinone-8
Neisseria gonorrhoeae
7.2.1.1
ubiquinone-8
the enzyme contains one ubiquinone-8
Neisseria meningitidis
7.2.1.1
ubiquinone-8
the enzyme contains one ubiquinone-8
Porphyromonas gingivalis
7.2.1.1
ubiquinone-8
the enzyme contains one ubiquinone-8
Pseudomonas aeruginosa
7.2.1.1
ubiquinone-8
the enzyme contains one ubiquinone-8
Vibrio alginolyticus
7.2.1.1
ubiquinone-8
the enzyme contains one ubiquinone-8
Vibrio cholerae
7.2.1.1
ubiquinone-8
the enzyme contains one ubiquinone-8
Vibrio harveyi
7.2.1.1
ubiquinone-8
the enzyme contains one ubiquinone-8
Yersinia pestis
7.2.1.1
[2Fe-2S]-center
part of the NqrF subunit of Na+-NQR
Azotobacter vinelandii
7.2.1.1
[2Fe-2S]-center
part of the NqrF subunit of Na+-NQR
Haemophilus influenzae
7.2.1.1
[2Fe-2S]-center
part of the NqrF subunit of Na+-NQR
Klebsiella pneumoniae
7.2.1.1
[2Fe-2S]-center
part of the NqrF subunit of Na+-NQR
Neisseria gonorrhoeae
7.2.1.1
[2Fe-2S]-center
part of the NqrF subunit of Na+-NQR
Neisseria meningitidis
7.2.1.1
[2Fe-2S]-center
part of the NqrF subunit of Na+-NQR
Porphyromonas gingivalis
7.2.1.1
[2Fe-2S]-center
part of the NqrF subunit of Na+-NQR
Pseudomonas aeruginosa
7.2.1.1
[2Fe-2S]-center
part of the NqrF subunit of Na+-NQR
Vibrio alginolyticus
7.2.1.1
[2Fe-2S]-center
part of the NqrF subunit of Na+-NQR
Vibrio cholerae
7.2.1.1
[2Fe-2S]-center
part of the NqrF subunit of Na+-NQR
Vibrio harveyi
7.2.1.1
[2Fe-2S]-center
part of the NqrF subunit of Na+-NQR
Yersinia pestis
Cofactor (protein specific)
EC Number
Cofactor
Commentary
Organism
Structure
7.2.1.1
FAD
noncovalently bound to the NqrF subunit of Na+-NQR
Azotobacter vinelandii
7.2.1.1
FAD
noncovalently bound to the NqrF subunit of Na+-NQR
Haemophilus influenzae
7.2.1.1
FAD
noncovalently bound to the NqrF subunit of Na+-NQR
Klebsiella pneumoniae
7.2.1.1
FAD
noncovalently bound to the NqrF subunit of Na+-NQR
Neisseria gonorrhoeae
7.2.1.1
FAD
noncovalently bound to the NqrF subunit of Na+-NQR
Neisseria meningitidis
7.2.1.1
FAD
noncovalently bound to the NqrF subunit of Na+-NQR
Porphyromonas gingivalis
7.2.1.1
FAD
noncovalently bound to the NqrF subunit of Na+-NQR
Pseudomonas aeruginosa
7.2.1.1
FAD
noncovalently bound to the NqrF subunit of Na+-NQR
Vibrio alginolyticus
7.2.1.1
FAD
noncovalently bound to the NqrF subunit of Na+-NQR
Vibrio cholerae
7.2.1.1
FAD
noncovalently bound to the NqrF subunit of Na+-NQR
Vibrio harveyi
7.2.1.1
FAD
noncovalently bound to the NqrF subunit of Na+-NQR
Yersinia pestis
7.2.1.1
FMN
covalently bound to the NqrB and NqrC subunits of Na+-NQR
Azotobacter vinelandii
7.2.1.1
FMN
covalently bound to the NqrB and NqrC subunits of Na+-NQR
Haemophilus influenzae
7.2.1.1
FMN
covalently bound to the NqrB and NqrC subunits of Na+-NQR
Klebsiella pneumoniae
7.2.1.1
FMN
covalently bound to the NqrB and NqrC subunits of Na+-NQR
Neisseria gonorrhoeae
7.2.1.1
FMN
covalently bound to the NqrB and NqrC subunits of Na+-NQR
Neisseria meningitidis
7.2.1.1
FMN
covalently bound to the NqrB and NqrC subunits of Na+-NQR
Porphyromonas gingivalis
7.2.1.1
FMN
covalently bound to the NqrB and NqrC subunits of Na+-NQR
Pseudomonas aeruginosa
7.2.1.1
FMN
covalently bound to the NqrB and NqrC subunits of Na+-NQR
Vibrio alginolyticus
7.2.1.1
FMN
covalently bound to the NqrB and NqrC subunits of Na+-NQR
Vibrio cholerae
7.2.1.1
FMN
covalently bound to the NqrB and NqrC subunits of Na+-NQR
Vibrio harveyi
7.2.1.1
FMN
covalently bound to the NqrB and NqrC subunits of Na+-NQR
Yersinia pestis
7.2.1.1
NADH
Na+-NQR is specific to NADH
Azotobacter vinelandii
7.2.1.1
NADH
Na+-NQR is specific to NADH
Haemophilus influenzae
7.2.1.1
NADH
Na+-NQR is specific to NADH
Klebsiella pneumoniae
7.2.1.1
NADH
Na+-NQR is specific to NADH
Neisseria gonorrhoeae
7.2.1.1
NADH
Na+-NQR is specific to NADH
Neisseria meningitidis
7.2.1.1
NADH
Na+-NQR is specific to NADH
Porphyromonas gingivalis
7.2.1.1
NADH
Na+-NQR is specific to NADH
Pseudomonas aeruginosa
7.2.1.1
NADH
Na+-NQR is specific to NADH
Vibrio alginolyticus
7.2.1.1
NADH
Na+-NQR is specific to NADH
Vibrio cholerae
7.2.1.1
NADH
Na+-NQR is specific to NADH
Vibrio harveyi
7.2.1.1
NADH
Na+-NQR is specific to NADH
Yersinia pestis
7.2.1.1
riboflavin
the enzyme contains one noncovalently bound riboflavin
Azotobacter vinelandii
7.2.1.1
riboflavin
the enzyme contains one noncovalently bound riboflavin
Haemophilus influenzae
7.2.1.1
riboflavin
the enzyme contains one noncovalently bound riboflavin
Klebsiella pneumoniae
7.2.1.1
riboflavin
the enzyme contains one noncovalently bound riboflavin
Neisseria gonorrhoeae
7.2.1.1
riboflavin
the enzyme contains one noncovalently bound riboflavin
Neisseria meningitidis
7.2.1.1
riboflavin
the enzyme contains one noncovalently bound riboflavin
Porphyromonas gingivalis
7.2.1.1
riboflavin
the enzyme contains one noncovalently bound riboflavin
Pseudomonas aeruginosa
7.2.1.1
riboflavin
the enzyme contains one noncovalently bound riboflavin
Vibrio alginolyticus
7.2.1.1
riboflavin
the enzyme contains one noncovalently bound riboflavin
Vibrio cholerae
7.2.1.1
riboflavin
the enzyme contains one noncovalently bound riboflavin
Vibrio harveyi
7.2.1.1
riboflavin
the enzyme contains one noncovalently bound riboflavin
Yersinia pestis
7.2.1.1
ubiquinone-8
the enzyme contains one ubiquinone-8
Azotobacter vinelandii
7.2.1.1
ubiquinone-8
the enzyme contains one ubiquinone-8
Haemophilus influenzae
7.2.1.1
ubiquinone-8
the enzyme contains one ubiquinone-8
Klebsiella pneumoniae
7.2.1.1
ubiquinone-8
the enzyme contains one ubiquinone-8
Neisseria gonorrhoeae
7.2.1.1
ubiquinone-8
the enzyme contains one ubiquinone-8
Neisseria meningitidis
7.2.1.1
ubiquinone-8
the enzyme contains one ubiquinone-8
Porphyromonas gingivalis
7.2.1.1
ubiquinone-8
the enzyme contains one ubiquinone-8
Pseudomonas aeruginosa
7.2.1.1
ubiquinone-8
the enzyme contains one ubiquinone-8
Vibrio alginolyticus
7.2.1.1
ubiquinone-8
the enzyme contains one ubiquinone-8
Vibrio cholerae
7.2.1.1
ubiquinone-8
the enzyme contains one ubiquinone-8
Vibrio harveyi
7.2.1.1
ubiquinone-8
the enzyme contains one ubiquinone-8
Yersinia pestis
7.2.1.1
[2Fe-2S]-center
part of the NqrF subunit of Na+-NQR
Azotobacter vinelandii
7.2.1.1
[2Fe-2S]-center
part of the NqrF subunit of Na+-NQR
Haemophilus influenzae
7.2.1.1
[2Fe-2S]-center
part of the NqrF subunit of Na+-NQR
Klebsiella pneumoniae
7.2.1.1
[2Fe-2S]-center
part of the NqrF subunit of Na+-NQR
Neisseria gonorrhoeae
7.2.1.1
[2Fe-2S]-center
part of the NqrF subunit of Na+-NQR
Neisseria meningitidis
7.2.1.1
[2Fe-2S]-center
part of the NqrF subunit of Na+-NQR
Porphyromonas gingivalis
7.2.1.1
[2Fe-2S]-center
part of the NqrF subunit of Na+-NQR
Pseudomonas aeruginosa
7.2.1.1
[2Fe-2S]-center
part of the NqrF subunit of Na+-NQR
Vibrio alginolyticus
7.2.1.1
[2Fe-2S]-center
part of the NqrF subunit of Na+-NQR
Vibrio cholerae
7.2.1.1
[2Fe-2S]-center
part of the NqrF subunit of Na+-NQR
Vibrio harveyi
7.2.1.1
[2Fe-2S]-center
part of the NqrF subunit of Na+-NQR
Yersinia pestis
Inhibitors (protein specific)
EC Number
Inhibitors
Commentary
Organism
Structure
7.2.1.1
2-n-heptyl-4-hydroxyquinoline-N-oxide
-
Haemophilus influenzae
7.2.1.1
2-n-heptyl-4-hydroxyquinoline-N-oxide
-
Klebsiella pneumoniae
7.2.1.1
2-n-heptyl-4-hydroxyquinoline-N-oxide
-
Neisseria gonorrhoeae
7.2.1.1
2-n-heptyl-4-hydroxyquinoline-N-oxide
-
Neisseria meningitidis
7.2.1.1
2-n-heptyl-4-hydroxyquinoline-N-oxide
-
Porphyromonas gingivalis
7.2.1.1
2-n-heptyl-4-hydroxyquinoline-N-oxide
-
Pseudomonas aeruginosa
7.2.1.1
2-n-heptyl-4-hydroxyquinoline-N-oxide
-
Vibrio alginolyticus
7.2.1.1
2-n-heptyl-4-hydroxyquinoline-N-oxide
-
Vibrio harveyi
7.2.1.1
2-n-heptyl-4-hydroxyquinoline-N-oxide
-
Yersinia pestis
7.2.1.1
2-n-heptyl-4-hydroxyquinoline-N-oxide
-
Vibrio cholerae
7.2.1.1
Ag+
-
Azotobacter vinelandii
7.2.1.1
Ag+
-
Haemophilus influenzae
7.2.1.1
Ag+
-
Neisseria gonorrhoeae
7.2.1.1
Ag+
-
Neisseria meningitidis
7.2.1.1
Ag+
-
Porphyromonas gingivalis
7.2.1.1
Ag+
-
Pseudomonas aeruginosa
7.2.1.1
Ag+
-
Vibrio cholerae
7.2.1.1
Ag+
-
Vibrio harveyi
7.2.1.1
Ag+
-
Yersinia pestis
7.2.1.1
Ag+
-
Vibrio alginolyticus
7.2.1.1
Cd2+
-
Azotobacter vinelandii
7.2.1.1
Cd2+
-
Haemophilus influenzae
7.2.1.1
Cd2+
-
Klebsiella pneumoniae
7.2.1.1
Cd2+
-
Neisseria gonorrhoeae
7.2.1.1
Cd2+
-
Neisseria meningitidis
7.2.1.1
Cd2+
-
Porphyromonas gingivalis
7.2.1.1
Cd2+
-
Pseudomonas aeruginosa
7.2.1.1
Cd2+
-
Vibrio alginolyticus
7.2.1.1
Cd2+
-
Vibrio cholerae
7.2.1.1
Cd2+
-
Vibrio harveyi
7.2.1.1
Cd2+
-
Yersinia pestis
7.2.1.1
Cu2+
-
Azotobacter vinelandii
7.2.1.1
Cu2+
-
Haemophilus influenzae
7.2.1.1
Cu2+
-
Klebsiella pneumoniae
7.2.1.1
Cu2+
-
Neisseria gonorrhoeae
7.2.1.1
Cu2+
-
Neisseria meningitidis
7.2.1.1
Cu2+
-
Porphyromonas gingivalis
7.2.1.1
Cu2+
-
Pseudomonas aeruginosa
7.2.1.1
Cu2+
-
Vibrio alginolyticus
7.2.1.1
Cu2+
-
Vibrio cholerae
7.2.1.1
Cu2+
-
Vibrio harveyi
7.2.1.1
Cu2+
-
Yersinia pestis
7.2.1.1
korormicin
specifically inhibits Na+-NQR at the level of its interaction with ubiquinone
Azotobacter vinelandii
7.2.1.1
korormicin
specifically inhibits Na+-NQR at the level of its interaction with ubiquinone
Klebsiella pneumoniae
7.2.1.1
korormicin
specifically inhibits Na+-NQR at the level of its interaction with ubiquinone
Neisseria gonorrhoeae
7.2.1.1
korormicin
specifically inhibits Na+-NQR at the level of its interaction with ubiquinone
Neisseria meningitidis
7.2.1.1
korormicin
specifically inhibits Na+-NQR at the level of its interaction with ubiquinone
Porphyromonas gingivalis
7.2.1.1
korormicin
specifically inhibits Na+-NQR at the level of its interaction with ubiquinone
Pseudomonas aeruginosa
7.2.1.1
korormicin
specifically inhibits Na+-NQR at the level of its interaction with ubiquinone
Vibrio alginolyticus
7.2.1.1
korormicin
specifically inhibits Na+-NQR at the level of its interaction with ubiquinone
Vibrio cholerae
7.2.1.1
korormicin
specifically inhibits Na+-NQR at the level of its interaction with ubiquinone
Vibrio harveyi
7.2.1.1
korormicin
specifically inhibits Na+-NQR at the level of its interaction with ubiquinone
Yersinia pestis
7.2.1.1
additional information
Na+-NQR from Azotobacter vinelandii is not sensitive to low 2-n-heptyl-4-hydroxyquinoline-N-oxide concentrations
Azotobacter vinelandii
7.2.1.1
additional information
korormicin has no effect on the enzyme from Haemophilus influenza
Haemophilus influenzae
7.2.1.1
additional information
Na+-NQR from Klebsiella pneumoniae is fully resistant to either Ag+ or N-ethylmaleimide
Klebsiella pneumoniae
7.2.1.1
N-ethylmaleimide
-
Azotobacter vinelandii
7.2.1.1
N-ethylmaleimide
-
Haemophilus influenzae
7.2.1.1
N-ethylmaleimide
-
Neisseria gonorrhoeae
7.2.1.1
N-ethylmaleimide
-
Neisseria meningitidis
7.2.1.1
N-ethylmaleimide
-
Porphyromonas gingivalis
7.2.1.1
N-ethylmaleimide
-
Pseudomonas aeruginosa
7.2.1.1
N-ethylmaleimide
-
Vibrio alginolyticus
7.2.1.1
N-ethylmaleimide
-
Vibrio cholerae
7.2.1.1
N-ethylmaleimide
-
Vibrio harveyi
7.2.1.1
N-ethylmaleimide
-
Yersinia pestis
7.2.1.1
Pb2+
-
Azotobacter vinelandii
7.2.1.1
Pb2+
-
Haemophilus influenzae
7.2.1.1
Pb2+
-
Klebsiella pneumoniae
7.2.1.1
Pb2+
-
Neisseria gonorrhoeae
7.2.1.1
Pb2+
-
Neisseria meningitidis
7.2.1.1
Pb2+
-
Porphyromonas gingivalis
7.2.1.1
Pb2+
-
Pseudomonas aeruginosa
7.2.1.1
Pb2+
-
Vibrio alginolyticus
7.2.1.1
Pb2+
-
Vibrio cholerae
7.2.1.1
Pb2+
-
Vibrio harveyi
7.2.1.1
Pb2+
-
Yersinia pestis
7.2.1.1
Zn2+
-
Azotobacter vinelandii
7.2.1.1
Zn2+
-
Haemophilus influenzae
7.2.1.1
Zn2+
-
Klebsiella pneumoniae
7.2.1.1
Zn2+
-
Neisseria gonorrhoeae
7.2.1.1
Zn2+
-
Neisseria meningitidis
7.2.1.1
Zn2+
-
Porphyromonas gingivalis
7.2.1.1
Zn2+
-
Pseudomonas aeruginosa
7.2.1.1
Zn2+
-
Vibrio alginolyticus
7.2.1.1
Zn2+
-
Vibrio cholerae
7.2.1.1
Zn2+
-
Vibrio harveyi
7.2.1.1
Zn2+
-
Yersinia pestis
Metals/Ions (protein specific)
EC Number
Metals/Ions
Commentary
Organism
Structure
7.2.1.1
Na+
specific requirement for sodium ions, even in the absence of sodium ions Na+-NQR is unable to translocate protons
Azotobacter vinelandii
7.2.1.1
Na+
specific requirement for sodium ions, even in the absence of sodium ions Na+-NQR is unable to translocate protons
Haemophilus influenzae
7.2.1.1
Na+
specific requirement for sodium ions, even in the absence of sodium ions Na+-NQR is unable to translocate protons
Klebsiella pneumoniae
7.2.1.1
Na+
specific requirement for sodium ions, even in the absence of sodium ions Na+-NQR is unable to translocate protons
Neisseria gonorrhoeae
7.2.1.1
Na+
specific requirement for sodium ions, even in the absence of sodium ions Na+-NQR is unable to translocate protons
Neisseria meningitidis
7.2.1.1
Na+
specific requirement for sodium ions, even in the absence of sodium ions Na+-NQR is unable to translocate protons
Porphyromonas gingivalis
7.2.1.1
Na+
specific requirement for sodium ions, even in the absence of sodium ions Na+-NQR is unable to translocate protons
Pseudomonas aeruginosa
7.2.1.1
Na+
specific requirement for sodium ions, even in the absence of sodium ions Na+-NQR is unable to translocate protons
Vibrio alginolyticus
7.2.1.1
Na+
specific requirement for sodium ions, even in the absence of sodium ions Na+-NQR is unable to translocate protons
Vibrio cholerae
7.2.1.1
Na+
specific requirement for sodium ions, even in the absence of sodium ions Na+-NQR is unable to translocate protons
Vibrio harveyi
7.2.1.1
Na+
specific requirement for sodium ions, even in the absence of sodium ions Na+-NQR is unable to translocate protons
Yersinia pestis
Molecular Weight [Da] (protein specific)
EC Number
Molecular Weight [Da]
Molecular Weight Maximum [Da]
Commentary
Organism
7.2.1.1
21500
-
1 * 48400 + 1 * 45400 + 1 * 27500 + 1 * 22700 + 1 * 21500 + 1 * 45200, calculated from amino acid sequence
Vibrio harveyi
7.2.1.1
22700
-
1 * 48400 + 1 * 45400 + 1 * 27500 + 1 * 22700 + 1 * 21500 + 1 * 45200, calculated from amino acid sequence
Vibrio harveyi
7.2.1.1
27500
-
1 * 48400 + 1 * 45400 + 1 * 27500 + 1 * 22700 + 1 * 21500 + 1 * 45200, calculated from amino acid sequence
Vibrio harveyi
7.2.1.1
45200
-
1 * 48400 + 1 * 45400 + 1 * 27500 + 1 * 22700 + 1 * 21500 + 1 * 45200, calculated from amino acid sequence
Vibrio harveyi
7.2.1.1
45400
-
1 * 48400 + 1 * 45400 + 1 * 27500 + 1 * 22700 + 1 * 21500 + 1 * 45200, calculated from amino acid sequence
Vibrio harveyi
7.2.1.1
48400
-
1 * 48400 + 1 * 45400 + 1 * 27500 + 1 * 22700 + 1 * 21500 + 1 * 45200, calculated from amino acid sequence
Vibrio harveyi
Natural Substrates/ Products (Substrates) (protein specific)
EC Number
Natural Substrates
Organism
Commentary (Nat. Sub.)
Natural Products
Commentary (Nat. Pro.)
Organism (Nat. Pro.)
Reversibility
7.2.1.1
deamino-NADH + H+ + ubiquinone + 2 Na+/in
Haemophilus influenzae
-
deamino-NAD+ + ubiquinol + 2 Na+/out
-
-
?
7.2.1.1
deamino-NADH + H+ + ubiquinone + 2 Na+/in
Vibrio harveyi
-
deamino-NAD+ + ubiquinol + 2 Na+/out
-
-
?
7.2.1.1
deamino-NADH + H+ + ubiquinone + 2 Na+/in
Pseudomonas aeruginosa
-
deamino-NAD+ + ubiquinol + 2 Na+/out
-
-
?
7.2.1.1
deamino-NADH + H+ + ubiquinone + 2 Na+/in
Neisseria gonorrhoeae
-
deamino-NAD+ + ubiquinol + 2 Na+/out
-
-
?
7.2.1.1
deamino-NADH + H+ + ubiquinone + 2 Na+/in
Neisseria meningitidis
-
deamino-NAD+ + ubiquinol + 2 Na+/out
-
-
?
7.2.1.1
deamino-NADH + H+ + ubiquinone + 2 Na+/in
Klebsiella pneumoniae
-
deamino-NAD+ + ubiquinol + 2 Na+/out
-
-
?
7.2.1.1
deamino-NADH + H+ + ubiquinone + 2 Na+/in
Azotobacter vinelandii
-
deamino-NAD+ + ubiquinol + 2 Na+/out
-
-
?
7.2.1.1
deamino-NADH + H+ + ubiquinone + 2 Na+/in
Yersinia pestis
-
deamino-NAD+ + ubiquinol + 2 Na+/out
-
-
?
7.2.1.1
deamino-NADH + H+ + ubiquinone + 2 Na+/in
Porphyromonas gingivalis
-
deamino-NAD+ + ubiquinol + 2 Na+/out
-
-
?
7.2.1.1
deamino-NADH + H+ + ubiquinone + 2 Na+/in
Vibrio cholerae
-
deamino-NAD+ + ubiquinol + 2 Na+/out
-
-
?
7.2.1.1
deamino-NADH + H+ + ubiquinone + 2 Na+/in
Vibrio alginolyticus
-
deamino-NAD+ + ubiquinol + 2 Na+/out
-
-
?
7.2.1.1
additional information
Haemophilus influenzae
in addition to the quinone reductase reaction, the isolated enzyme can also catalyze the so-called NADH-dehydrogenase reaction during interaction with soluble quinones. This activity includes a single-electron reduction of soluble quinones (menadione, Q0, Q1, etc.) or some other electron acceptors (hexaammineruthenium (III), ferricyanide, etc.)
?
-
-
-
7.2.1.1
additional information
Vibrio harveyi
in addition to the quinone reductase reaction, the isolated enzyme can also catalyze the so-called NADH-dehydrogenase reaction during interaction with soluble quinones. This activity includes a single-electron reduction of soluble quinones (menadione, Q0, Q1, etc.) or some other electron acceptors (hexaammineruthenium (III), ferricyanide, etc.)
?
-
-
-
7.2.1.1
additional information
Pseudomonas aeruginosa
in addition to the quinone reductase reaction, the isolated enzyme can also catalyze the so-called NADH-dehydrogenase reaction during interaction with soluble quinones. This activity includes a single-electron reduction of soluble quinones (menadione, Q0, Q1, etc.) or some other electron acceptors (hexaammineruthenium (III), ferricyanide, etc.)
?
-
-
-
7.2.1.1
additional information
Neisseria gonorrhoeae
in addition to the quinone reductase reaction, the isolated enzyme can also catalyze the so-called NADH-dehydrogenase reaction during interaction with soluble quinones. This activity includes a single-electron reduction of soluble quinones (menadione, Q0, Q1, etc.) or some other electron acceptors (hexaammineruthenium (III), ferricyanide, etc.)
?
-
-
-
7.2.1.1
additional information
Neisseria meningitidis
in addition to the quinone reductase reaction, the isolated enzyme can also catalyze the so-called NADH-dehydrogenase reaction during interaction with soluble quinones. This activity includes a single-electron reduction of soluble quinones (menadione, Q0, Q1, etc.) or some other electron acceptors (hexaammineruthenium (III), ferricyanide, etc.)
?
-
-
-
7.2.1.1
additional information
Klebsiella pneumoniae
in addition to the quinone reductase reaction, the isolated enzyme can also catalyze the so-called NADH-dehydrogenase reaction during interaction with soluble quinones. This activity includes a single-electron reduction of soluble quinones (menadione, Q0, Q1, etc.) or some other electron acceptors (hexaammineruthenium (III), ferricyanide, etc.)
?
-
-
-
7.2.1.1
additional information
Azotobacter vinelandii
in addition to the quinone reductase reaction, the isolated enzyme can also catalyze the so-called NADH-dehydrogenase reaction during interaction with soluble quinones. This activity includes a single-electron reduction of soluble quinones (menadione, Q0, Q1, etc.) or some other electron acceptors (hexaammineruthenium (III), ferricyanide, etc.)
?
-
-
-
7.2.1.1
additional information
Yersinia pestis
in addition to the quinone reductase reaction, the isolated enzyme can also catalyze the so-called NADH-dehydrogenase reaction during interaction with soluble quinones. This activity includes a single-electron reduction of soluble quinones (menadione, Q0, Q1, etc.) or some other electron acceptors (hexaammineruthenium (III), ferricyanide, etc.)
?
-
-
-
7.2.1.1
additional information
Porphyromonas gingivalis
in addition to the quinone reductase reaction, the isolated enzyme can also catalyze the so-called NADH-dehydrogenase reaction during interaction with soluble quinones. This activity includes a single-electron reduction of soluble quinones (menadione, Q0, Q1, etc.) or some other electron acceptors (hexaammineruthenium (III), ferricyanide, etc.)
?
-
-
-
7.2.1.1
additional information
Vibrio cholerae
in addition to the quinone reductase reaction, the isolated enzyme can also catalyze the so-called NADH-dehydrogenase reaction during interaction with soluble quinones. This activity includes a single-electron reduction of soluble quinones (menadione, Q0, Q1, etc.) or some other electron acceptors (hexaammineruthenium (III), ferricyanide, etc.)
?
-
-
-
7.2.1.1
additional information
Vibrio alginolyticus
in addition to the quinone reductase reaction, the isolated enzyme can also catalyze the so-called NADH-dehydrogenase reaction during interaction with soluble quinones. This activity includes a single-electron reduction of soluble quinones (menadione, Q0, Q1, etc.) or some other electron acceptors (hexaammineruthenium (III), ferricyanide, etc.)
?
-
-
-
7.2.1.1
additional information
Haemophilus influenzae
Na+-NQR does not oxidize NADPH
?
-
-
-
7.2.1.1
additional information
Vibrio harveyi
Na+-NQR does not oxidize NADPH
?
-
-
-
7.2.1.1
additional information
Pseudomonas aeruginosa
Na+-NQR does not oxidize NADPH
?
-
-
-
7.2.1.1
additional information
Neisseria gonorrhoeae
Na+-NQR does not oxidize NADPH
?
-
-
-
7.2.1.1
additional information
Neisseria meningitidis
Na+-NQR does not oxidize NADPH
?
-
-
-
7.2.1.1
additional information
Klebsiella pneumoniae
Na+-NQR does not oxidize NADPH
?
-
-
-
7.2.1.1
additional information
Azotobacter vinelandii
Na+-NQR does not oxidize NADPH
?
-
-
-
7.2.1.1
additional information
Yersinia pestis
Na+-NQR does not oxidize NADPH
?
-
-
-
7.2.1.1
additional information
Porphyromonas gingivalis
Na+-NQR does not oxidize NADPH
?
-
-
-
7.2.1.1
additional information
Vibrio cholerae
Na+-NQR does not oxidize NADPH
?
-
-
-
7.2.1.1
additional information
Vibrio alginolyticus
Na+-NQR does not oxidize NADPH
?
-
-
-
7.2.1.1
NADH + H+ + ubiquinone + 2 Na+/in
Haemophilus influenzae
-
NAD+ + ubiquinol + 2 Na+/out
-
-
?
7.2.1.1
NADH + H+ + ubiquinone + 2 Na+/in
Vibrio harveyi
-
NAD+ + ubiquinol + 2 Na+/out
-
-
?
7.2.1.1
NADH + H+ + ubiquinone + 2 Na+/in
Pseudomonas aeruginosa
-
NAD+ + ubiquinol + 2 Na+/out
-
-
?
7.2.1.1
NADH + H+ + ubiquinone + 2 Na+/in
Neisseria gonorrhoeae
-
NAD+ + ubiquinol + 2 Na+/out
-
-
?
7.2.1.1
NADH + H+ + ubiquinone + 2 Na+/in
Neisseria meningitidis
-
NAD+ + ubiquinol + 2 Na+/out
-
-
?
7.2.1.1
NADH + H+ + ubiquinone + 2 Na+/in
Klebsiella pneumoniae
-
NAD+ + ubiquinol + 2 Na+/out
-
-
?
7.2.1.1
NADH + H+ + ubiquinone + 2 Na+/in
Azotobacter vinelandii
-
NAD+ + ubiquinol + 2 Na+/out
-
-
?
7.2.1.1
NADH + H+ + ubiquinone + 2 Na+/in
Yersinia pestis
-
NAD+ + ubiquinol + 2 Na+/out
-
-
?
7.2.1.1
NADH + H+ + ubiquinone + 2 Na+/in
Porphyromonas gingivalis
-
NAD+ + ubiquinol + 2 Na+/out
-
-
?
7.2.1.1
NADH + H+ + ubiquinone + 2 Na+/in
Vibrio cholerae
-
NAD+ + ubiquinol + 2 Na+/out
-
-
?
7.2.1.1
NADH + H+ + ubiquinone + 2 Na+/in
Vibrio alginolyticus
-
NAD+ + ubiquinol + 2 Na+/out
-
-
?
7.2.1.1
thio-NADH + H+ + ubiquinone + 2 Na+/in
Haemophilus influenzae
-
thio-NAD+ + ubiquinol + 2 Na+/out
-
-
?
7.2.1.1
thio-NADH + H+ + ubiquinone + 2 Na+/in
Vibrio harveyi
-
thio-NAD+ + ubiquinol + 2 Na+/out
-
-
?
7.2.1.1
thio-NADH + H+ + ubiquinone + 2 Na+/in
Pseudomonas aeruginosa
-
thio-NAD+ + ubiquinol + 2 Na+/out
-
-
?
7.2.1.1
thio-NADH + H+ + ubiquinone + 2 Na+/in
Neisseria gonorrhoeae
-
thio-NAD+ + ubiquinol + 2 Na+/out
-
-
?
7.2.1.1
thio-NADH + H+ + ubiquinone + 2 Na+/in
Neisseria meningitidis
-
thio-NAD+ + ubiquinol + 2 Na+/out
-
-
?
7.2.1.1
thio-NADH + H+ + ubiquinone + 2 Na+/in
Klebsiella pneumoniae
-
thio-NAD+ + ubiquinol + 2 Na+/out
-
-
?
7.2.1.1
thio-NADH + H+ + ubiquinone + 2 Na+/in
Azotobacter vinelandii
-
thio-NAD+ + ubiquinol + 2 Na+/out
-
-
?
7.2.1.1
thio-NADH + H+ + ubiquinone + 2 Na+/in
Yersinia pestis
-
thio-NAD+ + ubiquinol + 2 Na+/out
-
-
?
7.2.1.1
thio-NADH + H+ + ubiquinone + 2 Na+/in
Porphyromonas gingivalis
-
thio-NAD+ + ubiquinol + 2 Na+/out
-
-
?
7.2.1.1
thio-NADH + H+ + ubiquinone + 2 Na+/in
Vibrio cholerae
-
thio-NAD+ + ubiquinol + 2 Na+/out
-
-
?
7.2.1.1
thio-NADH + H+ + ubiquinone + 2 Na+/in
Vibrio alginolyticus
-
thio-NAD+ + ubiquinol + 2 Na+/out
-
-
?
Substrates and Products (Substrate) (protein specific)
EC Number
Substrates
Commentary Substrates
Literature (Substrates)
Organism
Products
Commentary (Products)
Literature (Products)
Organism (Products)
Reversibility
7.2.1.1
deamino-NADH + H+ + ubiquinone + 2 Na+/in
-
711293
Haemophilus influenzae
deamino-NAD+ + ubiquinol + 2 Na+/out
-
-
-
?
7.2.1.1
deamino-NADH + H+ + ubiquinone + 2 Na+/in
-
711293
Vibrio harveyi
deamino-NAD+ + ubiquinol + 2 Na+/out
-
-
-
?
7.2.1.1
deamino-NADH + H+ + ubiquinone + 2 Na+/in
-
711293
Pseudomonas aeruginosa
deamino-NAD+ + ubiquinol + 2 Na+/out
-
-
-
?
7.2.1.1
deamino-NADH + H+ + ubiquinone + 2 Na+/in
-
711293
Neisseria gonorrhoeae
deamino-NAD+ + ubiquinol + 2 Na+/out
-
-
-
?
7.2.1.1
deamino-NADH + H+ + ubiquinone + 2 Na+/in
-
711293
Neisseria meningitidis
deamino-NAD+ + ubiquinol + 2 Na+/out
-
-
-
?
7.2.1.1
deamino-NADH + H+ + ubiquinone + 2 Na+/in
-
711293
Klebsiella pneumoniae
deamino-NAD+ + ubiquinol + 2 Na+/out
-
-
-
?
7.2.1.1
deamino-NADH + H+ + ubiquinone + 2 Na+/in
-
711293
Azotobacter vinelandii
deamino-NAD+ + ubiquinol + 2 Na+/out
-
-
-
?
7.2.1.1
deamino-NADH + H+ + ubiquinone + 2 Na+/in
-
711293
Yersinia pestis
deamino-NAD+ + ubiquinol + 2 Na+/out
-
-
-
?
7.2.1.1
deamino-NADH + H+ + ubiquinone + 2 Na+/in
-
711293
Porphyromonas gingivalis
deamino-NAD+ + ubiquinol + 2 Na+/out
-
-
-
?
7.2.1.1
deamino-NADH + H+ + ubiquinone + 2 Na+/in
-
711293
Vibrio cholerae
deamino-NAD+ + ubiquinol + 2 Na+/out
-
-
-
?
7.2.1.1
deamino-NADH + H+ + ubiquinone + 2 Na+/in
-
711293
Vibrio alginolyticus
deamino-NAD+ + ubiquinol + 2 Na+/out
-
-
-
?
7.2.1.1
additional information
in addition to the quinone reductase reaction, the isolated enzyme can also catalyze the so-called NADH-dehydrogenase reaction during interaction with soluble quinones. This activity includes a single-electron reduction of soluble quinones (menadione, Q0, Q1, etc.) or some other electron acceptors (hexaammineruthenium (III), ferricyanide, etc.)
711293
Haemophilus influenzae
?
-
-
-
-
7.2.1.1
additional information
in addition to the quinone reductase reaction, the isolated enzyme can also catalyze the so-called NADH-dehydrogenase reaction during interaction with soluble quinones. This activity includes a single-electron reduction of soluble quinones (menadione, Q0, Q1, etc.) or some other electron acceptors (hexaammineruthenium (III), ferricyanide, etc.)
711293
Vibrio harveyi
?
-
-
-
-
7.2.1.1
additional information
in addition to the quinone reductase reaction, the isolated enzyme can also catalyze the so-called NADH-dehydrogenase reaction during interaction with soluble quinones. This activity includes a single-electron reduction of soluble quinones (menadione, Q0, Q1, etc.) or some other electron acceptors (hexaammineruthenium (III), ferricyanide, etc.)
711293
Pseudomonas aeruginosa
?
-
-
-
-
7.2.1.1
additional information
in addition to the quinone reductase reaction, the isolated enzyme can also catalyze the so-called NADH-dehydrogenase reaction during interaction with soluble quinones. This activity includes a single-electron reduction of soluble quinones (menadione, Q0, Q1, etc.) or some other electron acceptors (hexaammineruthenium (III), ferricyanide, etc.)
711293
Neisseria gonorrhoeae
?
-
-
-
-
7.2.1.1
additional information
in addition to the quinone reductase reaction, the isolated enzyme can also catalyze the so-called NADH-dehydrogenase reaction during interaction with soluble quinones. This activity includes a single-electron reduction of soluble quinones (menadione, Q0, Q1, etc.) or some other electron acceptors (hexaammineruthenium (III), ferricyanide, etc.)
711293
Neisseria meningitidis
?
-
-
-
-
7.2.1.1
additional information
in addition to the quinone reductase reaction, the isolated enzyme can also catalyze the so-called NADH-dehydrogenase reaction during interaction with soluble quinones. This activity includes a single-electron reduction of soluble quinones (menadione, Q0, Q1, etc.) or some other electron acceptors (hexaammineruthenium (III), ferricyanide, etc.)
711293
Klebsiella pneumoniae
?
-
-
-
-
7.2.1.1
additional information
in addition to the quinone reductase reaction, the isolated enzyme can also catalyze the so-called NADH-dehydrogenase reaction during interaction with soluble quinones. This activity includes a single-electron reduction of soluble quinones (menadione, Q0, Q1, etc.) or some other electron acceptors (hexaammineruthenium (III), ferricyanide, etc.)
711293
Azotobacter vinelandii
?
-
-
-
-
7.2.1.1
additional information
in addition to the quinone reductase reaction, the isolated enzyme can also catalyze the so-called NADH-dehydrogenase reaction during interaction with soluble quinones. This activity includes a single-electron reduction of soluble quinones (menadione, Q0, Q1, etc.) or some other electron acceptors (hexaammineruthenium (III), ferricyanide, etc.)
711293
Yersinia pestis
?
-
-
-
-
7.2.1.1
additional information
in addition to the quinone reductase reaction, the isolated enzyme can also catalyze the so-called NADH-dehydrogenase reaction during interaction with soluble quinones. This activity includes a single-electron reduction of soluble quinones (menadione, Q0, Q1, etc.) or some other electron acceptors (hexaammineruthenium (III), ferricyanide, etc.)
711293
Porphyromonas gingivalis
?
-
-
-
-
7.2.1.1
additional information
in addition to the quinone reductase reaction, the isolated enzyme can also catalyze the so-called NADH-dehydrogenase reaction during interaction with soluble quinones. This activity includes a single-electron reduction of soluble quinones (menadione, Q0, Q1, etc.) or some other electron acceptors (hexaammineruthenium (III), ferricyanide, etc.)
711293
Vibrio cholerae
?
-
-
-
-
7.2.1.1
additional information
in addition to the quinone reductase reaction, the isolated enzyme can also catalyze the so-called NADH-dehydrogenase reaction during interaction with soluble quinones. This activity includes a single-electron reduction of soluble quinones (menadione, Q0, Q1, etc.) or some other electron acceptors (hexaammineruthenium (III), ferricyanide, etc.)
711293
Vibrio alginolyticus
?
-
-
-
-
7.2.1.1
additional information
Na+-NQR does not oxidize NADPH
711293
Haemophilus influenzae
?
-
-
-
-
7.2.1.1
additional information
Na+-NQR does not oxidize NADPH
711293
Vibrio harveyi
?
-
-
-
-
7.2.1.1
additional information
Na+-NQR does not oxidize NADPH
711293
Pseudomonas aeruginosa
?
-
-
-
-
7.2.1.1
additional information
Na+-NQR does not oxidize NADPH
711293
Neisseria gonorrhoeae
?
-
-
-
-
7.2.1.1
additional information
Na+-NQR does not oxidize NADPH
711293
Neisseria meningitidis
?
-
-
-
-
7.2.1.1
additional information
Na+-NQR does not oxidize NADPH
711293
Klebsiella pneumoniae
?
-
-
-
-
7.2.1.1
additional information
Na+-NQR does not oxidize NADPH
711293
Azotobacter vinelandii
?
-
-
-
-
7.2.1.1
additional information
Na+-NQR does not oxidize NADPH
711293
Yersinia pestis
?
-
-
-
-
7.2.1.1
additional information
Na+-NQR does not oxidize NADPH
711293
Porphyromonas gingivalis
?
-
-
-
-
7.2.1.1
additional information
Na+-NQR does not oxidize NADPH
711293
Vibrio cholerae
?
-
-
-
-
7.2.1.1
additional information
Na+-NQR does not oxidize NADPH
711293
Vibrio alginolyticus
?
-
-
-
-
7.2.1.1
NADH + H+ + ubiquinone + 2 Na+/in
-
711293
Haemophilus influenzae
NAD+ + ubiquinol + 2 Na+/out
-
-
-
?
7.2.1.1
NADH + H+ + ubiquinone + 2 Na+/in
-
711293
Vibrio harveyi
NAD+ + ubiquinol + 2 Na+/out
-
-
-
?
7.2.1.1
NADH + H+ + ubiquinone + 2 Na+/in
-
711293
Pseudomonas aeruginosa
NAD+ + ubiquinol + 2 Na+/out
-
-
-
?
7.2.1.1
NADH + H+ + ubiquinone + 2 Na+/in
-
711293
Neisseria gonorrhoeae
NAD+ + ubiquinol + 2 Na+/out
-
-
-
?
7.2.1.1
NADH + H+ + ubiquinone + 2 Na+/in
-
711293
Neisseria meningitidis
NAD+ + ubiquinol + 2 Na+/out
-
-
-
?
7.2.1.1
NADH + H+ + ubiquinone + 2 Na+/in
-
711293
Klebsiella pneumoniae
NAD+ + ubiquinol + 2 Na+/out
-
-
-
?
7.2.1.1
NADH + H+ + ubiquinone + 2 Na+/in
-
711293
Azotobacter vinelandii
NAD+ + ubiquinol + 2 Na+/out
-
-
-
?
7.2.1.1
NADH + H+ + ubiquinone + 2 Na+/in
-
711293
Yersinia pestis
NAD+ + ubiquinol + 2 Na+/out
-
-
-
?
7.2.1.1
NADH + H+ + ubiquinone + 2 Na+/in
-
711293
Porphyromonas gingivalis
NAD+ + ubiquinol + 2 Na+/out
-
-
-
?
7.2.1.1
NADH + H+ + ubiquinone + 2 Na+/in
-
711293
Vibrio cholerae
NAD+ + ubiquinol + 2 Na+/out
-
-
-
?
7.2.1.1
NADH + H+ + ubiquinone + 2 Na+/in
-
711293
Vibrio alginolyticus
NAD+ + ubiquinol + 2 Na+/out
-
-
-
?
7.2.1.1
thio-NADH + H+ + ubiquinone + 2 Na+/in
-
711293
Haemophilus influenzae
thio-NAD+ + ubiquinol + 2 Na+/out
-
-
-
?
7.2.1.1
thio-NADH + H+ + ubiquinone + 2 Na+/in
-
711293
Vibrio harveyi
thio-NAD+ + ubiquinol + 2 Na+/out
-
-
-
?
7.2.1.1
thio-NADH + H+ + ubiquinone + 2 Na+/in
-
711293
Pseudomonas aeruginosa
thio-NAD+ + ubiquinol + 2 Na+/out
-
-
-
?
7.2.1.1
thio-NADH + H+ + ubiquinone + 2 Na+/in
-
711293
Neisseria gonorrhoeae
thio-NAD+ + ubiquinol + 2 Na+/out
-
-
-
?
7.2.1.1
thio-NADH + H+ + ubiquinone + 2 Na+/in
-
711293
Neisseria meningitidis
thio-NAD+ + ubiquinol + 2 Na+/out
-
-
-
?
7.2.1.1
thio-NADH + H+ + ubiquinone + 2 Na+/in
-
711293
Klebsiella pneumoniae
thio-NAD+ + ubiquinol + 2 Na+/out
-
-
-
?
7.2.1.1
thio-NADH + H+ + ubiquinone + 2 Na+/in
-
711293
Azotobacter vinelandii
thio-NAD+ + ubiquinol + 2 Na+/out
-
-
-
?
7.2.1.1
thio-NADH + H+ + ubiquinone + 2 Na+/in
-
711293
Yersinia pestis
thio-NAD+ + ubiquinol + 2 Na+/out
-
-
-
?
7.2.1.1
thio-NADH + H+ + ubiquinone + 2 Na+/in
-
711293
Porphyromonas gingivalis
thio-NAD+ + ubiquinol + 2 Na+/out
-
-
-
?
7.2.1.1
thio-NADH + H+ + ubiquinone + 2 Na+/in
-
711293
Vibrio cholerae
thio-NAD+ + ubiquinol + 2 Na+/out
-
-
-
?
7.2.1.1
thio-NADH + H+ + ubiquinone + 2 Na+/in
-
711293
Vibrio alginolyticus
thio-NAD+ + ubiquinol + 2 Na+/out
-
-
-
?
Subunits (protein specific)
EC Number
Subunits
Commentary
Organism
7.2.1.1
heterohexamer
1 * 48400 + 1 * 45400 + 1 * 27500 + 1 * 22700 + 1 * 21500 + 1 * 45200, calculated from amino acid sequence
Vibrio harveyi