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Literature summary extracted from

  • Novick, R.; Vezina, C.; Elfarra, A.
    Isoform distinct time-, dose-, and castration-dependent alterations in flavin-containing monooxygenase expression in mouse liver after 2,3,7,8-tetrachlorodibenzo-p-dioxin treatment (2010), Biochem. Pharmacol., 79, 1345-1351.
    View publication on PubMedView publication on EuropePMC

Localization

EC Number Localization Comment Organism GeneOntology No. Textmining
1.14.13.8 microsome
-
 Mus musculus
-
-

Natural Substrates/ Products (Substrates)

EC Number Natural Substrates Organism Comment (Nat. Sub.) Natural Products Comment (Nat. Pro.) Rev. Reac.
1.14.13.8 additional information Mus musculus flavin-containing monooxygenases catalyze the addition of oxygen to many sulfur-, nitrogen-, phosphorus-, and selenium-containing compounds including pesticides, therapeutics, and dietary substances ?
-
 ?
1.14.13.8 additional information Mus musculus C57/BL6J flavin-containing monooxygenases catalyze the addition of oxygen to many sulfur-, nitrogen-, phosphorus-, and selenium-containing compounds including pesticides, therapeutics, and dietary substances ?
-
 ?

Organism

EC Number Organism UniProt Comment Textmining
1.14.13.8 Mus musculus P50285 isozyme Fmo1, gene FMO1
-
1.14.13.8 Mus musculus P97501 isozyme Fmo3, gene FMO3
-
1.14.13.8 Mus musculus P97872 isozyme Fmo5, gene FMO5
-
1.14.13.8 Mus musculus Q8K2I3 isozyme Fmo2, gene FMO2
-
1.14.13.8 Mus musculus Q8VHG0 isozyme Fmo4, gene FMO4
-
1.14.13.8 Mus musculus C57/BL6J P50285 isozyme Fmo1, gene FMO1
-
1.14.13.8 Mus musculus C57/BL6J P97501 isozyme Fmo3, gene FMO3
-
1.14.13.8 Mus musculus C57/BL6J P97872 isozyme Fmo5, gene FMO5
-
1.14.13.8 Mus musculus C57/BL6J Q8K2I3 isozyme Fmo2, gene FMO2
-
1.14.13.8 Mus musculus C57/BL6J Q8VHG0 isozyme Fmo4, gene FMO4
-

Source Tissue

EC Number Source Tissue Comment Organism Textmining
1.14.13.8 liver
-
 Mus musculus
-

Substrates and Products (Substrate)

EC Number Substrates Comment Substrates Organism Products Comment (Products) Rev. Reac.
1.14.13.8 additional information flavin-containing monooxygenases catalyze the addition of oxygen to many sulfur-, nitrogen-, phosphorus-, and selenium-containing compounds including pesticides, therapeutics, and dietary substances Mus musculus ?
-
 ?
1.14.13.8 additional information flavin-containing monooxygenases catalyze the addition of oxygen to many sulfur-, nitrogen-, phosphorus-, and selenium-containing compounds including pesticides, therapeutics, and dietary substances Mus musculus C57/BL6J ?
-
 ?

Synonyms

EC Number Synonyms Comment Organism
1.14.13.8 FMO1
-
 Mus musculus
1.14.13.8 FMO2
-
 Mus musculus
1.14.13.8 FMO3
-
 Mus musculus
1.14.13.8 FMO4
-
 Mus musculus
1.14.13.8 FMO5
-
 Mus musculus

Expression

EC Number Organism Comment Expression
1.14.13.8 Mus musculus isozyme Fmo1 is not affected by 2,3,7,8-tetrachlorodibenzo-p-dioxin exposure or castration in contrast to other Fmo isozymes, overview additional information
1.14.13.8 Mus musculus isozyme Fmo2 is induced by 2,3,7,8-tetrachlorodibenzo-p-dioxin exposure or castration, 5fold and 20fold, respectively up
1.14.13.8 Mus musculus isozyme Fmo3 is induced by 2,3,7,8-tetrachlorodibenzo-p-dioxin exposure or castration, 130fold and 180fold, respectively up
1.14.13.8 Mus musculus isozyme Fmo4 is induced by castration, but not by exposure to 2,3,7,8-tetrachlorodibenzo-p-dioxin up