Any feedback?
Please rate this page
(literature.php)
(0/150)

BRENDA support

Literature summary extracted from

  • McKinnon, D.J.; Brzezowski, P.; Wilson, K.E.; Gray, G.R.
    Mitochondrial and chloroplastic targeting signals of NADP+-dependent isocitrate dehydrogenase (2009), Biochem. Cell Biol., 87, 963-974.
    View publication on PubMed

Cloned(Commentary)

EC Number Cloned (Comment) Organism
1.1.1.42 NADP+-ICDH contains two different translational ATG start sites, fusion of mitochondrial and chloroplastic targeting signals to YFP reporter, and transient expression in Nicotiana tabacum using Agrobacterium tumefaciens transfection method. The chloroplast-tageting signal constructs are localizes in the chloroplast, while the mitochondrial constructs are localized in either in mitochondria and chloroplasts, due to an 50 amino acid additional part that is added in expression in cultivars Xanthi and Petit Havana Nicotiana tabacum

Localization

EC Number Localization Comment Organism GeneOntology No. Textmining
1.1.1.42 chloroplast
-
 Nicotiana tabacum 9507
-
1.1.1.42 mitochondrion
-
 Nicotiana tabacum 5739
-

Natural Substrates/ Products (Substrates)

EC Number Natural Substrates Organism Comment (Nat. Sub.) Natural Products Comment (Nat. Pro.) Rev. Reac.
1.1.1.42 isocitrate + NADP+ Nicotiana tabacum
-
 2-oxoglutarate + NADPH + H+ + CO2
-
 ?

Organism

EC Number Organism UniProt Comment Textmining
1.1.1.42 Nicotiana tabacum O65853
-
-

Source Tissue

EC Number Source Tissue Comment Organism Textmining
1.1.1.42 leaf
-
 Nicotiana tabacum
-

Substrates and Products (Substrate)

EC Number Substrates Comment Substrates Organism Products Comment (Products) Rev. Reac.
1.1.1.42 isocitrate + NADP+
-
 Nicotiana tabacum 2-oxoglutarate + NADPH + H+ + CO2
-
 ?

Synonyms

EC Number Synonyms Comment Organism
1.1.1.42 NADP+-dependent isocitrate dehydrogenase
-
 Nicotiana tabacum
1.1.1.42 NADP+-ICDH belongs to a mutli-isoenzyme family Nicotiana tabacum

Cofactor

EC Number Cofactor Comment Organism Structure
1.1.1.42 NADP+
-
 Nicotiana tabacum