EC Number | Inhibitors | Comment | Organism | Structure |
---|---|---|---|---|
7.2.2.3 | adenosine | inhibits independently of the A3 receptor | Sus scrofa | |
7.2.2.3 | Furosemide | a Na+-ATPase specific inhibitor | Sus scrofa | |
7.2.2.3 | Inosine | inhibits independently of the A3 receptor | Sus scrofa | |
7.2.2.3 | additional information | adenine induces inhibition of Na+-ATPase activity | Sus scrofa |
EC Number | Localization | Comment | Organism | GeneOntology No. | Textmining |
---|---|---|---|---|---|
7.2.2.3 | membrane | - |
Sus scrofa | 16020 | - |
EC Number | Metals/Ions | Comment | Organism | Structure |
---|---|---|---|---|
7.2.2.3 | Mg2+ | required | Sus scrofa |
EC Number | Natural Substrates | Organism | Comment (Nat. Sub.) | Natural Products | Comment (Nat. Pro.) | Rev. | Reac. |
---|---|---|---|---|---|---|---|
7.2.2.3 | ATP + H2O + Na+/in | Sus scrofa | - |
ADP + phosphate + Na+/out | - |
? |
EC Number | Organism | UniProt | Comment | Textmining |
---|---|---|---|---|
7.2.2.3 | Sus scrofa | - |
- |
- |
EC Number | Purification (Comment) | Organism |
---|---|---|
7.2.2.3 | native enzyme from kidney cortex and basolateral membranes of proximal renal tubule cells | Sus scrofa |
EC Number | Source Tissue | Comment | Organism | Textmining |
---|---|---|---|---|
7.2.2.3 | kidney | - |
Sus scrofa | - |
7.2.2.3 | renal tubule | basolateral membranes of kidney proximal tubule cells | Sus scrofa | - |
EC Number | Substrates | Comment Substrates | Organism | Products | Comment (Products) | Rev. | Reac. |
---|---|---|---|---|---|---|---|
7.2.2.3 | ATP + H2O + Na+/in | - |
Sus scrofa | ADP + phosphate + Na+/out | - |
? |
EC Number | Synonyms | Comment | Organism |
---|---|---|---|
7.2.2.3 | renal Na+-ATPase | - |
Sus scrofa |
EC Number | pH Optimum Minimum | pH Optimum Maximum | Comment | Organism |
---|---|---|---|---|
7.2.2.3 | 7 | - |
assay at | Sus scrofa |
EC Number | General Information | Comment | Organism |
---|---|---|---|
7.2.2.3 | additional information | inosine-induced inhibition of Na+-ATPase activity could be involved in the increased renal sodium excretion during short periods of ischemia | Sus scrofa |