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Literature summary extracted from

  • Lopez-Sanchez, A.; Floriano, B.; Andujar, E.; Hernaez, M.J.; Santero, E.
    Tetralin-induced and ThnR-regulated aldehyde dehydrogenase and beta-oxidation genes in Sphingomonas macrogolitabida strain TFA (2010), Appl. Environ. Microbiol., 76, 110-118.
    View publication on PubMedView publication on EuropePMC

Activating Compound

EC Number Activating Compound Comment Organism Structure
1.2.1.3 additional information ThnG activity is not affected by the addition of 0.5 mM coenzyme A or dithiothreitol Sphingopyxis macrogoltabida

Cloned(Commentary)

EC Number Cloned (Comment) Organism
1.2.1.3 expressed in Escherichia coli C41 cells Sphingopyxis macrogoltabida

Protein Variants

EC Number Protein Variants Comment Organism
1.2.1.3 additional information the TFA T-668 mutant is obtained by insertion of a nonpolar KIXX cassette into the NaeI site of thnG, resulting in truncation of the gene beyond codon 169, the mutant shows reduced but clearly evident ALDH activity Sphingopyxis macrogoltabida

Organism

EC Number Organism UniProt Comment Textmining
1.2.1.3 Sphingopyxis macrogoltabida
-
-
-
1.2.1.3 Sphingopyxis macrogoltabida TFA
-
-
-

Substrates and Products (Substrate)

EC Number Substrates Comment Substrates Organism Products Comment (Products) Rev. Reac.
1.2.1.3 additional information no activity is detected when NADP+ is used as the oxidant instead of NAD+ Sphingopyxis macrogoltabida ?
-
 ?
1.2.1.3 additional information no activity is detected when NADP+ is used as the oxidant instead of NAD+ Sphingopyxis macrogoltabida TFA ?
-
 ?
1.2.1.3 pimelic semialdehyde + NAD+ + H2O
-
 Sphingopyxis macrogoltabida ?
-
 ?
1.2.1.3 pimelic semialdehyde + NAD+ + H2O
-
 Sphingopyxis macrogoltabida TFA ?
-
 ?

Synonyms

EC Number Synonyms Comment Organism
1.2.1.3 NAD+-pimelic semialdehyde-dependent aldehyde dehydrogenase
-
 Sphingopyxis macrogoltabida
1.2.1.3 ThnG
-
 Sphingopyxis macrogoltabida

Cofactor

EC Number Cofactor Comment Organism Structure
1.2.1.3 NAD+
-
 Sphingopyxis macrogoltabida