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Literature summary extracted from

  • Wendland, J.; Schaub, Y.; Walther, A.
    N-Acetylglucosamine utilization by Saccharomyces cerevisiae based on expression of Candida albicans NAG genes (2009), Appl. Environ. Microbiol., 75, 5840-5845.
    View publication on PubMedView publication on EuropePMC

Cloned(Commentary)

EC Number Cloned (Comment) Organism
3.5.1.25 NAG genes are expressed in Saccharomyces cerevisiae BY strains to study their effect on making novel carbon sources available for Saccharomyces cerevisiae Candida albicans
3.5.99.6 expressed in Saccharomyces cerevisiae strain BY Candida albicans

Natural Substrates/ Products (Substrates)

EC Number Natural Substrates Organism Comment (Nat. Sub.) Natural Products Comment (Nat. Pro.) Rev. Reac.
3.5.99.6 D-glucosamine 6-phosphate + H2O Candida albicans
-
D-fructose 6-phosphate + NH3
-
?
3.5.99.6 D-glucosamine 6-phosphate + H2O Candida albicans BWP17
-
D-fructose 6-phosphate + NH3
-
?

Organism

EC Number Organism UniProt Comment Textmining
3.5.1.25 Candida albicans
-
BWP17
-
3.5.99.6 Candida albicans
-
-
-
3.5.99.6 Candida albicans BWP17
-
-
-

Substrates and Products (Substrate)

EC Number Substrates Comment Substrates Organism Products Comment (Products) Rev. Reac.
3.5.1.25 N-acetyl-D-glucosamine 6-phosphate + H2O
-
Candida albicans D-glucosamine 6-phosphate + acetate
-
?
3.5.1.25 N-acetyl-D-glucosamine 6-phosphate + H2O
-
Candida albicans BWP17 D-glucosamine 6-phosphate + acetate
-
?
3.5.99.6 D-glucosamine 6-phosphate + H2O
-
Candida albicans D-fructose 6-phosphate + NH3
-
?
3.5.99.6 D-glucosamine 6-phosphate + H2O
-
Candida albicans BWP17 D-fructose 6-phosphate + NH3
-
?

Synonyms

EC Number Synonyms Comment Organism
3.5.1.25 CaNAG2/Dac1
-
Candida albicans
3.5.1.25 GlcNAc-6-phosphate deacetylase
-
Candida albicans
3.5.1.25 NAG2
-
Candida albicans
3.5.99.6 NAG1
-
Candida albicans

General Information

EC Number General Information Comment Organism
3.5.1.25 physiological function the Candida albicans genes encoding GlcNAc permease, GlcNAc kinase, GlcNAc-6-phosphate deacetylase, and glucosamine-6-phosphate deaminase are expressed in Saccharomyces cerevisiae strains to enable the use of GlcNAc as a carbon source. Chitin is the second abundant polysaccharide after cellulose and consists of N-acetylglucosamine moieties, which cannot be used by wild-type Saccharomyces cerevisiae Candida albicans