EC Number | Protein Variants | Comment | Organism |
---|---|---|---|
3.5.1.97 | additional information | the strain PAO1-DELTApvd is shown to be more virulent than the wild-type strain, confirming the role of PvdQ as a virulence-reducing agent | Pseudomonas aeruginosa PAO1 |
EC Number | Organism | UniProt | Comment | Textmining |
---|---|---|---|---|
3.5.1.97 | Pseudomonas aeruginosa PAO1 | - |
the virulence of Pseudomonas aeruginosa PAO1 is analyzed in a Caenorhabditis elegans infection model | - |
EC Number | Purification (Comment) | Organism |
---|---|---|
3.5.1.97 | a two-step purification protocol, anion exchange chromatography and hydrophobic interaction chromatography | Pseudomonas aeruginosa PAO1 |
EC Number | Source Tissue | Comment | Organism | Textmining |
---|---|---|---|---|
3.5.1.97 | additional information | in the Caenorhabditis elegans infection model it is observed that larval stage 1 to 3 benefit much more from the protection by PvdQ than larval stage 4 worms | Pseudomonas aeruginosa PAO1 | - |
EC Number | Substrates | Comment Substrates | Organism | Products | Comment (Products) | Rev. | Reac. |
---|---|---|---|---|---|---|---|
3.5.1.97 | N-3-oxododecanoyl-L-homoserine lactone + H2O | - |
Pseudomonas aeruginosa PAO1 | L-homoserine lactone + 3-oxododecanoic acid | - |
? |
EC Number | Synonyms | Comment | Organism |
---|---|---|---|
3.5.1.97 | acyl-homoserine lactone acylase | - |
Pseudomonas aeruginosa PAO1 |
3.5.1.97 | AHL acylase | - |
Pseudomonas aeruginosa PAO1 |
3.5.1.97 | PvdQ | - |
Pseudomonas aeruginosa PAO1 |
EC Number | Temperature Optimum [°C] | Temperature Optimum Maximum [°C] | Comment | Organism |
---|---|---|---|---|
3.5.1.97 | 37 | - |
assay at | Pseudomonas aeruginosa PAO1 |
EC Number | General Information | Comment | Organism |
---|---|---|---|
3.5.1.97 | physiological function | PvdQ functions as a quorum quencher in vitro. Purified PvdQ is added to Caenorhabditis elegans worms infected with wild-type PAO1 and this results in reduced pathogenicity and increases the life span of the nematodes. PvdQ might be a strong candidate for antibacterial therapy against Pseudomonas infections | Pseudomonas aeruginosa PAO1 |