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Literature summary extracted from
- High-performance liquid chromatography ultraviolet assay for human erythrocytic catalase activity by measuring glutathione as o-phthalaldehyde derivative (2011), Anal. Biochem., 410, 296-303.
Inhibitors
| EC Number | Inhibitors | Comment | Organism | Structure |
|---|---|---|---|---|
| 1.11.1.6 | 1H-[1,2,4]oxadiazolo[4,3-a]quinoxalin-1-one | - |
Homo sapiens |  |
| 1.11.1.6 | 3-Amino-1,2,4-triazole | very weak inhibitor of erythrocytic CAT activity | Homo sapiens | |
| 1.11.1.6 | azide | very strong inhibitor of erythrocytic CAT but a relatively weak CAT inhibitor in human hemolysates | Homo sapiens | |
| 1.11.1.6 | CAS 1609 | - |
Homo sapiens | |
| 1.11.1.6 | glycerol trinitrate | - |
Homo sapiens | |
| 1.11.1.6 | isosorbide dinitrate | - |
Homo sapiens | |
| 1.11.1.6 | additional information | acetazolamide and nitrate at concentrations up to 0.1 mM do not inhibit erythrocytic CAT activity | Homo sapiens | |
| 1.11.1.6 | nitrite | uncompetitive inhibitor | Homo sapiens | |
| 1.11.1.6 | pentaerythritol tetranitrate | - |
Homo sapiens | |
| 1.11.1.6 | S-nitrosoglutathione | - |
Homo sapiens | |
| 1.11.1.6 | sodium nitroprusside | - |
Homo sapiens | |
Organism
| EC Number | Organism | UniProt | Comment | Textmining |
|---|---|---|---|---|
| 1.11.1.6 | Homo sapiens | - |
- |
- |
Source Tissue
| EC Number | Source Tissue | Comment | Organism | Textmining |
|---|---|---|---|---|
| 1.11.1.6 | erythrocyte | - |
Homo sapiens | - |
Substrates and Products (Substrate)
| EC Number | Substrates | Comment Substrates | Organism | Products | Comment (Products) | Rev. | Reac. |
|---|---|---|---|---|---|---|---|
| 1.11.1.6 | H2O2 | - |
Homo sapiens | O2 + H2O | - |
? | |
Synonyms
| EC Number | Synonyms | Comment | Organism |
|---|---|---|---|
| 1.11.1.6 | CAT | - |
Homo sapiens |
| 1.11.1.6 | H2O2:H2O2 oxidoreductase | - |
Homo sapiens |
Cofactor
| EC Number | Cofactor | Comment | Organism | Structure |
|---|---|---|---|---|
| 1.11.1.6 | heme | - |
Homo sapiens | |
IC50 Value
| EC Number | IC50 Value | IC50 Value Maximum | Comment | Organism | Inhibitor | Structure |
|---|---|---|---|---|---|---|
| 1.11.1.6 | 0.0000002 | - |
erytrocyctic CAT, at 25°C, pH not specified in the publication | Homo sapiens | azide | |
| 1.11.1.6 | 0.009 | - |
erythrocytic CAT, at 25°C, pH not specified in the publication | Homo sapiens | nitrite | |
| 1.11.1.6 | 0.009 | - |
hemolysate CAT, at 25°C, pH not specified in the publication | Homo sapiens | azide | |
| 1.11.1.6 | 0.75 | - |
hemolysate CAT, at 25°C, pH not specified in the publication | Homo sapiens | nitrite | |
| 1.11.1.6 | 20 | - |
erythrocytic CAT, at 25°C, pH not specified in the publication | Homo sapiens | 3-Amino-1,2,4-triazole | |
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