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Literature summary extracted from
- Cell-based assay for screening 11beta-hydroxysteroid dehydrogenase 1 inhibitors (2009), Anal. Biochem., 392, 110-116.
Inhibitors
| EC Number | Inhibitors | Comment | Organism | Structure |
|---|---|---|---|---|
| 1.1.1.146 | carbenoxolone | - |
Mus musculus |  |
Organism
| EC Number | Organism | UniProt | Comment | Textmining |
|---|---|---|---|---|
| 1.1.1.146 | Mus musculus | - |
- |
- |
Source Tissue
| EC Number | Source Tissue | Comment | Organism | Textmining |
|---|---|---|---|---|
| 1.1.1.146 | C2C12 cell | myotube | Mus musculus | - |
Substrates and Products (Substrate)
| EC Number | Substrates | Comment Substrates | Organism | Products | Comment (Products) | Rev. | Reac. |
|---|---|---|---|---|---|---|---|
| 1.1.1.146 | cortisone + NADPH + H+ | - |
Mus musculus | cortisol + NADP+ | - |
? | |
Synonyms
| EC Number | Synonyms | Comment | Organism |
|---|---|---|---|
| 1.1.1.146 | 11beta-hydroxysteroid dehydrogenase 1 | - |
Mus musculus |
IC50 Value
| EC Number | IC50 Value | IC50 Value Maximum | Comment | Organism | Inhibitor | Structure |
|---|---|---|---|---|---|---|
| 1.1.1.146 | 0.000281 | - |
cell-based assay, pH not specified in the publication, temperature not specified in the publication | Mus musculus | carbenoxolone | |
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