BRENDA - Enzyme Database

The agmatine-degrading enzyme agmatinase: a key to agmatine signaling in rat and human brain?

Bernstein, H.G.; Derst, C.; Stich, C.; Pruess, H.; Peters, D.; Krauss, M.; Bogerts, B.; Veh, R.W.; Laube, G.; Amino Acids 40, 453-465 (2010)

Data extracted from this reference:

Natural Substrates/ Products (Substrates)
EC Number
Natural Substrates
Organism
Commentary (Nat. Sub.)
Natural Products
Commentary (Nat. Pro.)
Organism (Nat. Pro.)
Reversibility
3.5.3.11
agmatine + H2O
Homo sapiens
-
putrescine + urea
-
-
?
3.5.3.11
agmatine + H2O
Rattus norvegicus
-
putrescine + urea
-
-
?
Organism
EC Number
Organism
Primary Accession No. (UniProt)
Commentary
Textmining
3.5.3.11
Homo sapiens
-
-
-
3.5.3.11
Rattus norvegicus
-
-
-
Source Tissue
EC Number
Source Tissue
Commentary
Organism
Textmining
3.5.3.11
brain
-
Homo sapiens
-
3.5.3.11
brain
-
Rattus norvegicus
-
3.5.3.11
neuron
agmatinase is predominantly detected in distinct populations of neurons, especially cortical interneurons. Principal neurons in limbic regions like the habenula and in the cerebellum robustly express agmatinase protein
Homo sapiens
-
3.5.3.11
neuron
agmatinase is predominantly detected in distinct populations of neurons, especially cortical interneurons. Principal neurons in limbic regions like the habenula and in the cerebellum robustly express agmatinase protein
Rattus norvegicus
-
Substrates and Products (Substrate)
EC Number
Substrates
Commentary Substrates
Literature (Substrates)
Organism
Products
Commentary (Products)
Literature (Products)
Organism (Products)
Reversibility
3.5.3.11
agmatine + H2O
-
710833
Homo sapiens
putrescine + urea
-
-
-
?
3.5.3.11
agmatine + H2O
-
710833
Rattus norvegicus
putrescine + urea
-
-
-
?
Natural Substrates/ Products (Substrates) (protein specific)
EC Number
Natural Substrates
Organism
Commentary (Nat. Sub.)
Natural Products
Commentary (Nat. Pro.)
Organism (Nat. Pro.)
Reversibility
3.5.3.11
agmatine + H2O
Homo sapiens
-
putrescine + urea
-
-
?
3.5.3.11
agmatine + H2O
Rattus norvegicus
-
putrescine + urea
-
-
?
Source Tissue (protein specific)
EC Number
Source Tissue
Commentary
Organism
Textmining
3.5.3.11
brain
-
Homo sapiens
-
3.5.3.11
brain
-
Rattus norvegicus
-
3.5.3.11
neuron
agmatinase is predominantly detected in distinct populations of neurons, especially cortical interneurons. Principal neurons in limbic regions like the habenula and in the cerebellum robustly express agmatinase protein
Homo sapiens
-
3.5.3.11
neuron
agmatinase is predominantly detected in distinct populations of neurons, especially cortical interneurons. Principal neurons in limbic regions like the habenula and in the cerebellum robustly express agmatinase protein
Rattus norvegicus
-
Substrates and Products (Substrate) (protein specific)
EC Number
Substrates
Commentary Substrates
Literature (Substrates)
Organism
Products
Commentary (Products)
Literature (Products)
Organism (Products)
Reversibility
3.5.3.11
agmatine + H2O
-
710833
Homo sapiens
putrescine + urea
-
-
-
?
3.5.3.11
agmatine + H2O
-
710833
Rattus norvegicus
putrescine + urea
-
-
-
?