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Literature summary extracted from

  • Collings, I.; Watier, Y.; Giffard, M.; Dagogo, S.; Kahn, R.; Bonnete, F.; Wright, J.P.; Fitch, A.N.; Margiolaki, I.
    Polymorphism of microcrystalline urate oxidase from Aspergillus flavus (2010), Acta Crystallogr. Sect. D, 66, 539-548.
    View publication on PubMed

Cloned(Commentary)

EC Number Cloned (Comment) Organism
1.7.3.3 expressed in Saccharomyces cerevisiae Aspergillus flavus

Crystallization (Commentary)

EC Number Crystallization (Comment) Organism
1.7.3.3 ligand-free Uox crystallized with NH4Cl and 15% (w/v) PEG 8000, ligand-free Uox crystallized in water with 10% (w/v) PEG 8000, ligand-free Uox crystallized with NaCl and 15% (w/v) PEG 8000, ligand-free Uox crystallized with (NH4)2SO4 and 15% (w/v) PEG 8000, ligand-free Uox crystallized with NaCl and 8% PEG 8000, ligand-free Uox crystallized with KCl and 10% (w/v) PEG 8000, and Uox complexed with 8-azaxanthine and crystallized with NaCl and 10% (w/v) PEG 8000, in 50 mM Tris buffer pH 8.0 Aspergillus flavus

Inhibitors

EC Number Inhibitors Comment Organism Structure
1.7.3.3 8-Azaxanthine
-
Aspergillus flavus

Molecular Weight [Da]

EC Number Molecular Weight [Da] Molecular Weight Maximum [Da] Comment Organism
1.7.3.3 135000
-
-
Aspergillus flavus

Organism

EC Number Organism UniProt Comment Textmining
1.7.3.3 Aspergillus flavus Q00511
-
-

Purification (Commentary)

EC Number Purification (Comment) Organism
1.7.3.3 Superdex S200PG gel filtration Aspergillus flavus

Subunits

EC Number Subunits Comment Organism
1.7.3.3 homotetramer x-ray crystallography Aspergillus flavus

Synonyms

EC Number Synonyms Comment Organism
1.7.3.3 Rasburicase
-
Aspergillus flavus
1.7.3.3 Uox
-
Aspergillus flavus
1.7.3.3 Urate oxidase
-
Aspergillus flavus