Any feedback?
Please rate this page
(literature.php)
(0/150)

BRENDA support

Literature summary extracted from

  • Ellis, J.; Brown, J.
    The RNase P family (2009), RNA Biol., 6, 362-369.
    View publication on PubMed

Localization

EC Number Localization Comment Organism GeneOntology No. Textmining
3.1.26.5 chloroplast
-
Porphyra purpurea 9507
-
3.1.26.5 mitochondrion
-
Homo sapiens 5739
-
3.1.26.5 mitochondrion
-
Saccharomyces cerevisiae 5739
-
3.1.26.5 mitochondrion
-
Giardia intestinalis 5739
-
3.1.26.5 mitochondrion
-
Porphyra purpurea 5739
-
3.1.26.5 mitochondrion
-
Reclinomonas americana 5739
-
3.1.26.5 nucleus
-
Homo sapiens 5634
-
3.1.26.5 nucleus
-
Saccharomyces cerevisiae 5634
-
3.1.26.5 nucleus
-
Giardia intestinalis 5634
-
3.1.26.5 nucleus
-
Porphyra purpurea 5634
-
3.1.26.5 nucleus
-
Reclinomonas americana 5634
-

Organism

EC Number Organism UniProt Comment Textmining
3.1.26.5 Bacillus subtilis
-
-
-
3.1.26.5 Chlamydia trachomatis
-
-
-
3.1.26.5 Chlorobium limicola
-
-
-
3.1.26.5 Cupriavidus necator
-
-
-
3.1.26.5 Escherichia coli
-
-
-
3.1.26.5 Giardia intestinalis
-
-
-
3.1.26.5 Homo sapiens
-
-
-
3.1.26.5 Methanocaldococcus jannaschii
-
-
-
3.1.26.5 Methanothermobacter thermautotrophicus
-
-
-
3.1.26.5 Mycoplasma hyopneumoniae
-
-
-
3.1.26.5 Mycoplasmopsis fermentans
-
-
-
3.1.26.5 no activity in Aquifex aeolicus
-
-
-
3.1.26.5 Porphyra purpurea
-
-
-
3.1.26.5 Pyrobaculum aerophilum
-
-
-
3.1.26.5 Reclinomonas americana
-
-
-
3.1.26.5 Saccharomyces cerevisiae
-
-
-
3.1.26.5 Synechococcus elongatus PCC 6301
-
-
-
3.1.26.5 Thermomicrobium roseum
-
-
-

Substrates and Products (Substrate)

EC Number Substrates Comment Substrates Organism Products Comment (Products) Rev. Reac.
3.1.26.5 additional information cleaves riboswitchs Bacillus subtilis ?
-
?
3.1.26.5 additional information cleaves riboswitchs Escherichia coli ?
-
?
3.1.26.5 pre-tRNA + H2O
-
Homo sapiens tRNA + 5'-oligoribonucleotide
-
?

Synonyms

EC Number Synonyms Comment Organism
3.1.26.5 ribonuclease P
-
Chlorobium limicola
3.1.26.5 ribonuclease P
-
Chlamydia trachomatis
3.1.26.5 ribonuclease P
-
Bacillus subtilis
3.1.26.5 ribonuclease P
-
Escherichia coli
3.1.26.5 ribonuclease P
-
Homo sapiens
3.1.26.5 ribonuclease P
-
Saccharomyces cerevisiae
3.1.26.5 ribonuclease P
-
Methanothermobacter thermautotrophicus
3.1.26.5 ribonuclease P
-
Giardia intestinalis
3.1.26.5 ribonuclease P
-
Cupriavidus necator
3.1.26.5 ribonuclease P
-
Methanocaldococcus jannaschii
3.1.26.5 ribonuclease P
-
Mycoplasmopsis fermentans
3.1.26.5 ribonuclease P
-
Pyrobaculum aerophilum
3.1.26.5 ribonuclease P
-
Thermomicrobium roseum
3.1.26.5 ribonuclease P
-
Mycoplasma hyopneumoniae
3.1.26.5 ribonuclease P
-
Synechococcus elongatus PCC 6301
3.1.26.5 ribonuclease P
-
Porphyra purpurea
3.1.26.5 ribonuclease P
-
Reclinomonas americana
3.1.26.5 RNase P
-
Chlorobium limicola
3.1.26.5 RNase P
-
Chlamydia trachomatis
3.1.26.5 RNase P
-
Bacillus subtilis
3.1.26.5 RNase P
-
Escherichia coli
3.1.26.5 RNase P
-
Homo sapiens
3.1.26.5 RNase P
-
Saccharomyces cerevisiae
3.1.26.5 RNase P
-
Methanothermobacter thermautotrophicus
3.1.26.5 RNase P
-
Giardia intestinalis
3.1.26.5 RNase P
-
Cupriavidus necator
3.1.26.5 RNase P
-
Methanocaldococcus jannaschii
3.1.26.5 RNase P
-
Mycoplasmopsis fermentans
3.1.26.5 RNase P
-
Pyrobaculum aerophilum
3.1.26.5 RNase P
-
Thermomicrobium roseum
3.1.26.5 RNase P
-
Mycoplasma hyopneumoniae
3.1.26.5 RNase P
-
Synechococcus elongatus PCC 6301
3.1.26.5 RNase P
-
Porphyra purpurea
3.1.26.5 RNase P
-
Reclinomonas americana

General Information

EC Number General Information Comment Organism
3.1.26.5 physiological function mitochondrial RNase P RNA is primitive and recognizably similar to those of alpha-proteobacteria, the ancestors of mitochondria Reclinomonas americana
3.1.26.5 physiological function plastid RNase P RNA in the non-green alga is similar to those of their cyanobacterial ancestry Porphyra purpurea
3.1.26.5 physiological function the nuclear holoenzyme is comprised of protein subunits and RNase P RNA. In mitochondria, the usual RNA-containing RNase P is replaced by an enzyme composed of three proteins that are unrelated to RNase P enzymes in other systems (Rube Goldberg triad of unrelated proteins), but nevertheless are together responsible for the cleavage of pre-tRNA precursors Homo sapiens
3.1.26.5 physiological function the organism has distinct RNase P enzymes in the nucleus and mitochondria. The RNase P RNA from the mitochondrion is an example of a highly-derived (degenerate) mitochondrial RNase P RNA Saccharomyces cerevisiae
3.1.26.5 physiological function the RNase P holoenzyme is composed of a single RNA (type A1 RNase P RNA) and a single small protein subunit. Bacterial RNase P RNAs are comprised of two independently evolving domains, separated by P7. The RNA upstream and downstream of P7 contains all of the essential catalytic sequences and structures (C-domain). Changes in the RNA bound at each end by the two strands of P7 (the loop of P7) alter substrate specificity (S-domain). The RNA subunit is associated with a single, small conservative protein, encoded by the rnpA gene, which has an unusual left-handed betaalphabeta crossover connection and a large central cleft Escherichia coli
3.1.26.5 physiological function the RNase P holoenzyme is composed of a single RNA (type A2 RNase P RNA, lacks P13 and P14) and a single small protein subunit. Bacterial RNase P RNAs are comprised of two independently evolving domains, separated by P7. The RNA upstream and downstream of P7 contains all of the essential catalytic sequences and structures (C-domain). Changes in the RNA bound at each end by the two strands of P7 (the loop of P7) alter substrate specificity (S-domain). The RNA subunit is associated with a single, small conservative protein, encoded by the rnpA gene, which has an unusual left-handed betaalphabeta crossover connection and a large central cleft Cupriavidus necator
3.1.26.5 physiological function the RNase P holoenzyme is composed of a single RNA (type A3 RNase P RNA, with an altered L15 internal loop, in which the substrate 3'-NCCA tail is recognized) and a single small protein subunit. Bacterial RNase P RNAs are comprised of two independently evolving domains, separated by P7. The RNA upstream and downstream of P7 contains all of the essential catalytic sequences and structures (C-domain). Changes in the RNA bound at each end by the two strands of P7 (the loop of P7) alter substrate specificity (S-domain). The RNA subunit is associated with a single, small conservative protein, encoded by the rnpA gene, which has an unusual left-handed betaalphabeta crossover connection and a large central cleft Chlamydia trachomatis
3.1.26.5 physiological function the RNase P holoenzyme is composed of a single RNA (type A4 RNase P RNA, with an altered L15) and a single small protein subunit. Bacterial RNase P RNAs are comprised of two independently evolving domains, separated by P7. The RNA upstream and downstream of P7 contains all of the essential catalytic sequences and structures (C-domain). Changes in the RNA bound at each end by the two strands of P7 (the loop of P7) alter substrate specificity (S-domain). The RNA subunit is associated with a single, small conservative protein, encoded by the rnpA gene, which has an unusual left-handed betaalphabeta crossover connection and a large central cleft Synechococcus elongatus PCC 6301
3.1.26.5 physiological function the RNase P holoenzyme is composed of a single RNA (type A5 RNase P RNA, lacks P18) and a single small protein subunit. Bacterial RNase P RNAs are comprised of two independently evolving domains, separated by P7. The RNA upstream and downstream of P7 contains all of the essential catalytic sequences and structures (C-domain). Changes in the RNA bound at each end by the two strands of P7 (the loop of P7) alter substrate specificity (S-domain). The RNA subunit is associated with a single, small conservative protein, encoded by the rnpA gene, which has an unusual left-handed betaalphabeta crossover connection and a large central cleft Chlorobium limicola
3.1.26.5 physiological function the RNase P holoenzyme is composed of a single RNA (type B1 RNase P RNA) and a single small protein subunit. Bacterial RNase P RNAs are comprised of two independently evolving domains, separated by P7. The RNA upstream and downstream of P7 contains all of the essential catalytic sequences and structures (C-domain). Changes in the RNA bound at each end by the two strands of P7 (the loop of P7) alter substrate specificity (S-domain). The RNA subunit is associated with a single, small conservative protein, encoded by the rnpA gene, which has an unusual left-handed betaalphabeta crossover connection and a large central cleft Bacillus subtilis
3.1.26.5 physiological function the RNase P holoenzyme is composed of a single RNA (type B2 RNase P RNA, lacks P10.1) and a single small protein subunit. Bacterial RNase P RNAs are comprised of two independently evolving domains, separated by P7. The RNA upstream and downstream of P7 contains all of the essential catalytic sequences and structures (C-domain). Changes in the RNA bound at each end by the two strands of P7 (the loop of P7) alter substrate specificity (S-domain). The RNA subunit is associated with a single, small conservative protein, encoded by the rnpA gene, which has an unusual left-handed betaalphabeta crossover connection and a large central cleft Mycoplasma hyopneumoniae
3.1.26.5 physiological function the RNase P holoenzyme is composed of a single RNA (type B3 RNase P RNA, lacks P12) and a single small protein subunit. Bacterial RNase P RNAs are comprised of two independently evolving domains, separated by P7. The RNA upstream and downstream of P7 contains all of the essential catalytic sequences and structures (C-domain). Changes in the RNA bound at each end by the two strands of P7 (the loop of P7) alter substrate specificity (S-domain). The RNA subunit is associated with a single, small conservative protein, encoded by the rnpA gene, which has an unusual left-handed betaalphabeta crossover connection and a large central cleft Mycoplasmopsis fermentans
3.1.26.5 physiological function the RNase P holoenzyme is composed of a single RNA (type C RNase P RNA) and a single small protein subunit. Bacterial RNase P RNAs are comprised of two independently evolving domains, separated by P7. The RNA upstream and downstream of P7 contains all of the essential catalytic sequences and structures (C-domain). Changes in the RNA bound at each end by the two strands of P7 (the loop of P7) alter substrate specificity (S-domain). The RNA subunit is associated with a single, small conservative protein, encoded by the rnpA gene, which has an unusual left-handed betaalphabeta crossover connection and a large central cleft Thermomicrobium roseum
3.1.26.5 physiological function the RNase P holoenzyme is composed of a single RNA molecule (type A RNase P RNA) and several protein subunits Methanothermobacter thermautotrophicus
3.1.26.5 physiological function the RNase P holoenzyme is composed of a single RNA molecule (type M RNase P RNA, lacking P6, P8, P16 and P17) and several protein subunits Methanocaldococcus jannaschii
3.1.26.5 physiological function the RNase P holoenzyme is composed of a single RNA molecule (type T RNase P RNA, lacking the S-domain) and several protein subunits Pyrobaculum aerophilum