EC Number | Localization | Comment | Organism | GeneOntology No. | Textmining |
---|---|---|---|---|---|
3.1.26.5 | chloroplast | - |
Porphyra purpurea | 9507 | - |
3.1.26.5 | mitochondrion | - |
Homo sapiens | 5739 | - |
3.1.26.5 | mitochondrion | - |
Saccharomyces cerevisiae | 5739 | - |
3.1.26.5 | mitochondrion | - |
Giardia intestinalis | 5739 | - |
3.1.26.5 | mitochondrion | - |
Porphyra purpurea | 5739 | - |
3.1.26.5 | mitochondrion | - |
Reclinomonas americana | 5739 | - |
3.1.26.5 | nucleus | - |
Homo sapiens | 5634 | - |
3.1.26.5 | nucleus | - |
Saccharomyces cerevisiae | 5634 | - |
3.1.26.5 | nucleus | - |
Giardia intestinalis | 5634 | - |
3.1.26.5 | nucleus | - |
Porphyra purpurea | 5634 | - |
3.1.26.5 | nucleus | - |
Reclinomonas americana | 5634 | - |
EC Number | Organism | UniProt | Comment | Textmining |
---|---|---|---|---|
3.1.26.5 | Bacillus subtilis | - |
- |
- |
3.1.26.5 | Chlamydia trachomatis | - |
- |
- |
3.1.26.5 | Chlorobium limicola | - |
- |
- |
3.1.26.5 | Cupriavidus necator | - |
- |
- |
3.1.26.5 | Escherichia coli | - |
- |
- |
3.1.26.5 | Giardia intestinalis | - |
- |
- |
3.1.26.5 | Homo sapiens | - |
- |
- |
3.1.26.5 | Methanocaldococcus jannaschii | - |
- |
- |
3.1.26.5 | Methanothermobacter thermautotrophicus | - |
- |
- |
3.1.26.5 | Mycoplasma hyopneumoniae | - |
- |
- |
3.1.26.5 | Mycoplasmopsis fermentans | - |
- |
- |
3.1.26.5 | no activity in Aquifex aeolicus | - |
- |
- |
3.1.26.5 | Porphyra purpurea | - |
- |
- |
3.1.26.5 | Pyrobaculum aerophilum | - |
- |
- |
3.1.26.5 | Reclinomonas americana | - |
- |
- |
3.1.26.5 | Saccharomyces cerevisiae | - |
- |
- |
3.1.26.5 | Synechococcus elongatus PCC 6301 | - |
- |
- |
3.1.26.5 | Thermomicrobium roseum | - |
- |
- |
EC Number | Substrates | Comment Substrates | Organism | Products | Comment (Products) | Rev. | Reac. |
---|---|---|---|---|---|---|---|
3.1.26.5 | additional information | cleaves riboswitchs | Bacillus subtilis | ? | - |
? | |
3.1.26.5 | additional information | cleaves riboswitchs | Escherichia coli | ? | - |
? | |
3.1.26.5 | pre-tRNA + H2O | - |
Homo sapiens | tRNA + 5'-oligoribonucleotide | - |
? |
EC Number | Synonyms | Comment | Organism |
---|---|---|---|
3.1.26.5 | ribonuclease P | - |
Chlorobium limicola |
3.1.26.5 | ribonuclease P | - |
Chlamydia trachomatis |
3.1.26.5 | ribonuclease P | - |
Bacillus subtilis |
3.1.26.5 | ribonuclease P | - |
Escherichia coli |
3.1.26.5 | ribonuclease P | - |
Homo sapiens |
3.1.26.5 | ribonuclease P | - |
Saccharomyces cerevisiae |
3.1.26.5 | ribonuclease P | - |
Methanothermobacter thermautotrophicus |
3.1.26.5 | ribonuclease P | - |
Giardia intestinalis |
3.1.26.5 | ribonuclease P | - |
Cupriavidus necator |
3.1.26.5 | ribonuclease P | - |
Methanocaldococcus jannaschii |
3.1.26.5 | ribonuclease P | - |
Mycoplasmopsis fermentans |
3.1.26.5 | ribonuclease P | - |
Pyrobaculum aerophilum |
3.1.26.5 | ribonuclease P | - |
Thermomicrobium roseum |
3.1.26.5 | ribonuclease P | - |
Mycoplasma hyopneumoniae |
3.1.26.5 | ribonuclease P | - |
Synechococcus elongatus PCC 6301 |
3.1.26.5 | ribonuclease P | - |
Porphyra purpurea |
3.1.26.5 | ribonuclease P | - |
Reclinomonas americana |
3.1.26.5 | RNase P | - |
Chlorobium limicola |
3.1.26.5 | RNase P | - |
Chlamydia trachomatis |
3.1.26.5 | RNase P | - |
Bacillus subtilis |
3.1.26.5 | RNase P | - |
Escherichia coli |
3.1.26.5 | RNase P | - |
Homo sapiens |
3.1.26.5 | RNase P | - |
Saccharomyces cerevisiae |
3.1.26.5 | RNase P | - |
Methanothermobacter thermautotrophicus |
3.1.26.5 | RNase P | - |
Giardia intestinalis |
3.1.26.5 | RNase P | - |
Cupriavidus necator |
3.1.26.5 | RNase P | - |
Methanocaldococcus jannaschii |
3.1.26.5 | RNase P | - |
Mycoplasmopsis fermentans |
3.1.26.5 | RNase P | - |
Pyrobaculum aerophilum |
3.1.26.5 | RNase P | - |
Thermomicrobium roseum |
3.1.26.5 | RNase P | - |
Mycoplasma hyopneumoniae |
3.1.26.5 | RNase P | - |
Synechococcus elongatus PCC 6301 |
3.1.26.5 | RNase P | - |
Porphyra purpurea |
3.1.26.5 | RNase P | - |
Reclinomonas americana |
EC Number | General Information | Comment | Organism |
---|---|---|---|
3.1.26.5 | physiological function | mitochondrial RNase P RNA is primitive and recognizably similar to those of alpha-proteobacteria, the ancestors of mitochondria | Reclinomonas americana |
3.1.26.5 | physiological function | plastid RNase P RNA in the non-green alga is similar to those of their cyanobacterial ancestry | Porphyra purpurea |
3.1.26.5 | physiological function | the nuclear holoenzyme is comprised of protein subunits and RNase P RNA. In mitochondria, the usual RNA-containing RNase P is replaced by an enzyme composed of three proteins that are unrelated to RNase P enzymes in other systems (Rube Goldberg triad of unrelated proteins), but nevertheless are together responsible for the cleavage of pre-tRNA precursors | Homo sapiens |
3.1.26.5 | physiological function | the organism has distinct RNase P enzymes in the nucleus and mitochondria. The RNase P RNA from the mitochondrion is an example of a highly-derived (degenerate) mitochondrial RNase P RNA | Saccharomyces cerevisiae |
3.1.26.5 | physiological function | the RNase P holoenzyme is composed of a single RNA (type A1 RNase P RNA) and a single small protein subunit. Bacterial RNase P RNAs are comprised of two independently evolving domains, separated by P7. The RNA upstream and downstream of P7 contains all of the essential catalytic sequences and structures (C-domain). Changes in the RNA bound at each end by the two strands of P7 (the loop of P7) alter substrate specificity (S-domain). The RNA subunit is associated with a single, small conservative protein, encoded by the rnpA gene, which has an unusual left-handed betaalphabeta crossover connection and a large central cleft | Escherichia coli |
3.1.26.5 | physiological function | the RNase P holoenzyme is composed of a single RNA (type A2 RNase P RNA, lacks P13 and P14) and a single small protein subunit. Bacterial RNase P RNAs are comprised of two independently evolving domains, separated by P7. The RNA upstream and downstream of P7 contains all of the essential catalytic sequences and structures (C-domain). Changes in the RNA bound at each end by the two strands of P7 (the loop of P7) alter substrate specificity (S-domain). The RNA subunit is associated with a single, small conservative protein, encoded by the rnpA gene, which has an unusual left-handed betaalphabeta crossover connection and a large central cleft | Cupriavidus necator |
3.1.26.5 | physiological function | the RNase P holoenzyme is composed of a single RNA (type A3 RNase P RNA, with an altered L15 internal loop, in which the substrate 3'-NCCA tail is recognized) and a single small protein subunit. Bacterial RNase P RNAs are comprised of two independently evolving domains, separated by P7. The RNA upstream and downstream of P7 contains all of the essential catalytic sequences and structures (C-domain). Changes in the RNA bound at each end by the two strands of P7 (the loop of P7) alter substrate specificity (S-domain). The RNA subunit is associated with a single, small conservative protein, encoded by the rnpA gene, which has an unusual left-handed betaalphabeta crossover connection and a large central cleft | Chlamydia trachomatis |
3.1.26.5 | physiological function | the RNase P holoenzyme is composed of a single RNA (type A4 RNase P RNA, with an altered L15) and a single small protein subunit. Bacterial RNase P RNAs are comprised of two independently evolving domains, separated by P7. The RNA upstream and downstream of P7 contains all of the essential catalytic sequences and structures (C-domain). Changes in the RNA bound at each end by the two strands of P7 (the loop of P7) alter substrate specificity (S-domain). The RNA subunit is associated with a single, small conservative protein, encoded by the rnpA gene, which has an unusual left-handed betaalphabeta crossover connection and a large central cleft | Synechococcus elongatus PCC 6301 |
3.1.26.5 | physiological function | the RNase P holoenzyme is composed of a single RNA (type A5 RNase P RNA, lacks P18) and a single small protein subunit. Bacterial RNase P RNAs are comprised of two independently evolving domains, separated by P7. The RNA upstream and downstream of P7 contains all of the essential catalytic sequences and structures (C-domain). Changes in the RNA bound at each end by the two strands of P7 (the loop of P7) alter substrate specificity (S-domain). The RNA subunit is associated with a single, small conservative protein, encoded by the rnpA gene, which has an unusual left-handed betaalphabeta crossover connection and a large central cleft | Chlorobium limicola |
3.1.26.5 | physiological function | the RNase P holoenzyme is composed of a single RNA (type B1 RNase P RNA) and a single small protein subunit. Bacterial RNase P RNAs are comprised of two independently evolving domains, separated by P7. The RNA upstream and downstream of P7 contains all of the essential catalytic sequences and structures (C-domain). Changes in the RNA bound at each end by the two strands of P7 (the loop of P7) alter substrate specificity (S-domain). The RNA subunit is associated with a single, small conservative protein, encoded by the rnpA gene, which has an unusual left-handed betaalphabeta crossover connection and a large central cleft | Bacillus subtilis |
3.1.26.5 | physiological function | the RNase P holoenzyme is composed of a single RNA (type B2 RNase P RNA, lacks P10.1) and a single small protein subunit. Bacterial RNase P RNAs are comprised of two independently evolving domains, separated by P7. The RNA upstream and downstream of P7 contains all of the essential catalytic sequences and structures (C-domain). Changes in the RNA bound at each end by the two strands of P7 (the loop of P7) alter substrate specificity (S-domain). The RNA subunit is associated with a single, small conservative protein, encoded by the rnpA gene, which has an unusual left-handed betaalphabeta crossover connection and a large central cleft | Mycoplasma hyopneumoniae |
3.1.26.5 | physiological function | the RNase P holoenzyme is composed of a single RNA (type B3 RNase P RNA, lacks P12) and a single small protein subunit. Bacterial RNase P RNAs are comprised of two independently evolving domains, separated by P7. The RNA upstream and downstream of P7 contains all of the essential catalytic sequences and structures (C-domain). Changes in the RNA bound at each end by the two strands of P7 (the loop of P7) alter substrate specificity (S-domain). The RNA subunit is associated with a single, small conservative protein, encoded by the rnpA gene, which has an unusual left-handed betaalphabeta crossover connection and a large central cleft | Mycoplasmopsis fermentans |
3.1.26.5 | physiological function | the RNase P holoenzyme is composed of a single RNA (type C RNase P RNA) and a single small protein subunit. Bacterial RNase P RNAs are comprised of two independently evolving domains, separated by P7. The RNA upstream and downstream of P7 contains all of the essential catalytic sequences and structures (C-domain). Changes in the RNA bound at each end by the two strands of P7 (the loop of P7) alter substrate specificity (S-domain). The RNA subunit is associated with a single, small conservative protein, encoded by the rnpA gene, which has an unusual left-handed betaalphabeta crossover connection and a large central cleft | Thermomicrobium roseum |
3.1.26.5 | physiological function | the RNase P holoenzyme is composed of a single RNA molecule (type A RNase P RNA) and several protein subunits | Methanothermobacter thermautotrophicus |
3.1.26.5 | physiological function | the RNase P holoenzyme is composed of a single RNA molecule (type M RNase P RNA, lacking P6, P8, P16 and P17) and several protein subunits | Methanocaldococcus jannaschii |
3.1.26.5 | physiological function | the RNase P holoenzyme is composed of a single RNA molecule (type T RNase P RNA, lacking the S-domain) and several protein subunits | Pyrobaculum aerophilum |