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Literature summary extracted from

  • Yu, L.; Lee, T.; Lin, N.; Wolf, M.J.
    Affecting Rhomboid-3 function causes a dilated heart in adult Drosophila (2010), PLoS Genet., 6, e1000969.
    View publication on PubMedView publication on EuropePMC

Organism

EC Number Organism UniProt Comment Textmining
3.4.21.105 Drosophila melanogaster
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-
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Source Tissue

EC Number Source Tissue Comment Organism Textmining
3.4.21.105 embryo
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Drosophila melanogaster
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3.4.21.105 heart
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Drosophila melanogaster
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3.4.21.105 pupa
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Drosophila melanogaster
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Synonyms

EC Number Synonyms Comment Organism
3.4.21.105 rhomboid-3
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Drosophila melanogaster

General Information

EC Number General Information Comment Organism
3.4.21.105 malfunction using optical coherence tomography to examine the cardiac function in adult Drosophila from a set of molecularly defined genomic deficiencies an abnormally enlarged cardiac chamber in a series of deficiency mutants spanning the rhomboid 3 locus are identified. It is demonstrated that rhomboid 3 mediated activation of the EGF receptor pathway is necessary for proper adult cardiac function Drosophila melanogaster