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Literature summary extracted from

  • Lee, M.; Schwab, C.; Yu, S.; McGeer, E.; McGeer, P.L.
    Astrocytes produce the antiinflammatory and neuroprotective agent hydrogen sulfide (2009), Neurobiol. Aging, 30, 1523-1534.
    View publication on PubMed

Inhibitors

EC Number Inhibitors Comment Organism Structure
4.4.1.1 DL-propargylglycine
-
Homo sapiens

Molecular Weight [Da]

EC Number Molecular Weight [Da] Molecular Weight Maximum [Da] Comment Organism
4.4.1.1 43600
-
deduced from SDS-PAGE Homo sapiens

Organism

EC Number Organism UniProt Comment Textmining
4.4.1.1 Homo sapiens
-
-
-

Source Tissue

EC Number Source Tissue Comment Organism Textmining
4.4.1.1 astrocyte
-
Homo sapiens
-
4.4.1.1 brain
-
Homo sapiens
-
4.4.1.1 HUVEC cell
-
Homo sapiens
-
4.4.1.1 microglial cell
-
Homo sapiens
-
4.4.1.1 NTERA-2 cell
-
Homo sapiens
-
4.4.1.1 SH-SY5Y cell
-
Homo sapiens
-
4.4.1.1 THP-1 cell
-
Homo sapiens
-
4.4.1.1 U-118MG cell
-
Homo sapiens
-
4.4.1.1 U-373MG cell
-
Homo sapiens
-

Substrates and Products (Substrate)

EC Number Substrates Comment Substrates Organism Products Comment (Products) Rev. Reac.
4.4.1.1 L-cysteine + H2O
-
Homo sapiens sulfide + NH3 + pyruvate
-
?

Synonyms

EC Number Synonyms Comment Organism
4.4.1.1 cgl
-
Homo sapiens
4.4.1.1 cystathionase
-
Homo sapiens
4.4.1.1 cystathionine-gamma-lyase
-
Homo sapiens

Cofactor

EC Number Cofactor Comment Organism Structure
4.4.1.1 pyridoxal 5'-phosphate
-
Homo sapiens