EC Number | Cloned (Comment) | Organism |
---|---|---|
6.5.1.1 | expressed in Escherichia coli and in Sf9 insect cells | Homo sapiens |
EC Number | Inhibitors | Comment | Organism | Structure |
---|---|---|---|---|
6.5.1.1 | Replication factor C | LigI interacts with and is inhibited by replication factor C | Homo sapiens |
EC Number | Organism | UniProt | Comment | Textmining |
---|---|---|---|---|
6.5.1.1 | Homo sapiens | - |
- |
- |
EC Number | Posttranslational Modification | Comment | Organism |
---|---|---|---|
6.5.1.1 | phosphoprotein | phosphorylation of human DNA ligase I regulates its interaction with replication factor C and its participation in DNA replication and DNA repair | Homo sapiens |
EC Number | Purification (Comment) | Organism |
---|---|---|
6.5.1.1 | Sepharose column chromatography, Source Q column chromatography, and Superdex 200 gel filtration | Homo sapiens |
EC Number | Source Tissue | Comment | Organism | Textmining |
---|---|---|---|---|
6.5.1.1 | 46BR.1G1 cell | - |
Homo sapiens | - |
EC Number | Substrates | Comment Substrates | Organism | Products | Comment (Products) | Rev. | Reac. |
---|---|---|---|---|---|---|---|
6.5.1.1 | ATP + (deoxyribonucleotide)n + (deoxyribonucleotide)m | - |
Homo sapiens | AMP + diphosphate + (deoxyribonucleotide)n+m | - |
? |
EC Number | Synonyms | Comment | Organism |
---|---|---|---|
6.5.1.1 | DNA ligase I | - |
Homo sapiens |
6.5.1.1 | LigI | - |
Homo sapiens |
EC Number | Cofactor | Comment | Organism | Structure |
---|---|---|---|---|
6.5.1.1 | ATP | - |
Homo sapiens |