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Literature summary extracted from

  • Sikora, J.; Urinovská, J.; Majer, F.; Poupetová, H.; Hlavatá, J.; Kostrouchová, M.; Ledvinová, J.; Hrebícek, M.
    Bioinformatic and biochemical studies point to AAGR-1 as the ortholog of human acid alpha-glucosidase in Caenorhabditis elegans (2010), Mol. Cell. Biochem., 341, 51-63.
    View publication on PubMed

Inhibitors

EC Number Inhibitors Comment Organism Structure
3.2.1.20 acarbose with 0.008 mM acarbose about 60 to 99% decrease in alpha-glucosidase activity at pH 4.0, with 0.008 mM acarbose about 6 to 92% decrease in alpha-glucosidase activity at pH 6.5 Caenorhabditis elegans

Localization

EC Number Localization Comment Organism GeneOntology No. Textmining

Organism

EC Number Organism UniProt Comment Textmining
3.2.1.20 Caenorhabditis elegans
-
-
-

Substrates and Products (Substrate)

EC Number Substrates Comment Substrates Organism Products Comment (Products) Rev. Reac.
3.2.1.20 4-methylumbelliferyl alpha-D-glucopyranoside + H2O assay at pH 4.0 or 6.5, 37°C Caenorhabditis elegans 4-methylumbelliferone + alpha-D-glucose
-
 ?

Synonyms

EC Number Synonyms Comment Organism
3.2.1.20 AAGR-1
-
 Caenorhabditis elegans
3.2.1.20 AAGR-2
-
 Caenorhabditis elegans
3.2.1.20 AAGR-3
-
 Caenorhabditis elegans
3.2.1.20 AAGR-4
-
 Caenorhabditis elegans
3.2.1.20 acidic alpha-glucosidase
-
 Caenorhabditis elegans
3.2.1.20 alpha-glucosidase
-
 Caenorhabditis elegans
3.2.1.20 neutral alpha-glucosidase
-
 Caenorhabditis elegans

Temperature Optimum [°C]

EC Number Temperature Optimum [°C] Temperature Optimum Maximum [°C] Comment Organism
3.2.1.20 37
-
 assay at Caenorhabditis elegans

pH Optimum

EC Number pH Optimum Minimum pH Optimum Maximum Comment Organism
3.2.1.20 4
-
 assay at, impact on enzyme activity with inhibitor acarbose Caenorhabditis elegans
3.2.1.20 6.5
-
 assay at, impact on enzyme activity with inhibitor acarbose Caenorhabditis elegans