EC Number | Activating Compound | Comment | Organism | Structure |
---|---|---|---|---|
3.1.4.4 | L-ascorbic acid | activates the lipid signaling enzyme PLD at pharmacological doses, 5 mM, in the bovine lung microvascular endothelial cells, with modulation of PLD activation by phospholipase A2, PLA2. Antioxidants attenuate vitamin C-induced PLA2 , e.g. N-acetylcysteine, propyl gallate, or enzyme catalase activation | Bos taurus |
EC Number | Natural Substrates | Organism | Comment (Nat. Sub.) | Natural Products | Comment (Nat. Pro.) | Rev. | Reac. |
---|---|---|---|---|---|---|---|
3.1.4.4 | additional information | Bos taurus | PLD also performs transphosphatidylation using 1-butanol as phosphatidyl acceptor, the transphosphatidylation reaction is an index of PLD activity in intact cells | ? | - |
? |
EC Number | Organism | UniProt | Comment | Textmining |
---|---|---|---|---|
3.1.4.4 | Bos taurus | - |
- |
- |
EC Number | Source Tissue | Comment | Organism | Textmining |
---|---|---|---|---|
3.1.4.4 | lung | microvascular endothelial cells | Bos taurus | - |
3.1.4.4 | vascular endothelial cell | - |
Bos taurus | - |
EC Number | Specific Activity Minimum [µmol/min/mg] | Specific Activity Maximum [µmol/min/mg] | Comment | Organism |
---|---|---|---|---|
3.1.4.4 | additional information | - |
PLD transphosphatidylation activity at different conditions, overview | Bos taurus |
EC Number | Substrates | Comment Substrates | Organism | Products | Comment (Products) | Rev. | Reac. |
---|---|---|---|---|---|---|---|
3.1.4.4 | additional information | PLD also performs transphosphatidylation using 1-butanol as phosphatidyl acceptor, the transphosphatidylation reaction is an index of PLD activity in intact cells | Bos taurus | ? | - |
? |
EC Number | Synonyms | Comment | Organism |
---|---|---|---|
3.1.4.4 | PLD | - |
Bos taurus |