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Literature summary extracted from
- The three trehalases Nth1p, Nth2p and Ath1p participate in the mobilization of intracellular trehalose required for recovery from saline stress in Saccharomyces cerevisiae (2009), Microbiology, 155, 3092-3099.
Cloned(Commentary)
| EC Number | Cloned (Comment) | Organism |
|---|---|---|
| 3.2.1.28 | genes NTH1 and ATH1 | Saccharomyces cerevisiae |
Protein Variants
| EC Number | Protein Variants | Comment | Organism |
|---|---|---|---|
| 3.2.1.28 | additional information | construction of mutants defective in neutral trehalase and/or acid trehalase isozymes, metabolism phenotypes and viability, overview. The mutants show altered recovery from salt stress compared to the wild-type enzyme | Saccharomyces cerevisiae |
Localization
| EC Number | Localization | Comment | Organism | GeneOntology No. | Textmining |
|---|
Natural Substrates/ Products (Substrates)
| EC Number | Natural Substrates | Organism | Comment (Nat. Sub.) | Natural Products | Comment (Nat. Pro.) | Rev. | Reac. |
|---|---|---|---|---|---|---|---|
| 3.2.1.28 | trehalose + H2O | Saccharomyces cerevisiae | - |
2 D-glucose | - |
? |  |
| 3.2.1.28 | trehalose + H2O | Saccharomyces cerevisiae MCY1264 | - |
2 D-glucose | - |
? | |
Organism
| EC Number | Organism | UniProt | Comment | Textmining |
|---|---|---|---|---|
| 3.2.1.28 | Saccharomyces cerevisiae | - |
neutral trehalase and acid trehalase isozymes encoded by the NTH1 and ATH1 genes | - |
| 3.2.1.28 | Saccharomyces cerevisiae MCY1264 | - |
neutral trehalase and acid trehalase isozymes encoded by the NTH1 and ATH1 genes | - |
Substrates and Products (Substrate)
| EC Number | Substrates | Comment Substrates | Organism | Products | Comment (Products) | Rev. | Reac. |
|---|---|---|---|---|---|---|---|
| 3.2.1.28 | trehalose + H2O | - |
Saccharomyces cerevisiae | 2 D-glucose | - |
? | |
| 3.2.1.28 | trehalose + H2O | - |
Saccharomyces cerevisiae MCY1264 | 2 D-glucose | - |
? | |
Synonyms
| EC Number | Synonyms | Comment | Organism |
|---|---|---|---|
| 3.2.1.28 | acid trehalase | - |
Saccharomyces cerevisiae |
| 3.2.1.28 | neutral trehalase | - |
Saccharomyces cerevisiae |
General Information
| EC Number | General Information | Comment | Organism |
|---|---|---|---|
| 3.2.1.28 | physiological function | role for Nth2p in the mobilization of intracellular trehalose during salt-stress recovery, overview | Saccharomyces cerevisiae |
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Release 2023.1 (January 2023)
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