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Literature summary extracted from

  • Bair, W.B.; Cabello, C.M.; Uchida, K.; Bause, A.S.; Wondrak, G.T.
    GLO1 overexpression in human malignant melanoma (2010), Melanoma Res., 20, 85-96.
    View publication on PubMedView publication on EuropePMC

Organism

EC Number Organism UniProt Comment Textmining
4.4.1.5 Homo sapiens
-
-
-

Source Tissue

EC Number Source Tissue Comment Organism Textmining
4.4.1.5 A-375 cell
-
 Homo sapiens
-
4.4.1.5 G-361 cell
-
 Homo sapiens
-
4.4.1.5 melanoma cell
-
 Homo sapiens
-

Substrates and Products (Substrate)

EC Number Substrates Comment Substrates Organism Products Comment (Products) Rev. Reac.
4.4.1.5 methylglyoxal + glutathione
-
 Homo sapiens (R)-S-lactoylglutathione
-
 ?

Synonyms

EC Number Synonyms Comment Organism
4.4.1.5 Glo1
-
 Homo sapiens
4.4.1.5 glyoxalase I
-
 Homo sapiens

Cofactor

EC Number Cofactor Comment Organism Structure
4.4.1.5 glutathione
-
 Homo sapiens

Expression

EC Number Organism Comment Expression
4.4.1.5 Homo sapiens glyoxylase I expression is upregulated up to 10fold at the mRNA and protein level in metastatic melanoma tissue up