BRENDA - Enzyme Database

Recurrent emergence of catalytically inactive ornithine decarboxylase homologous forms that likely have regulatory function

Ivanov, I.P.; Firth, A.E.; Atkins, J.F.; J. Mol. Evol. 70, 289-302 (2010)

Data extracted from this reference:

Activating Compound
EC Number
Activating Compound
Commentary
Organism
Structure
4.1.1.17
additional information
antizyme inhibitors are homologs of ODC that have lost their decarboxylation activity but have retained their ability to bind the ODC inhibitor antizyme, in most cases even more tightly than ODC
Gallus gallus
4.1.1.17
additional information
antizyme inhibitors are homologs of ODC that have lost their decarboxylation activity but have retained their ability to bind the ODC inhibitor antizyme, in most cases even more tightly than ODC
Drosophila melanogaster
4.1.1.17
additional information
antizyme inhibitors are homologs of ODC that have lost their decarboxylation activity but have retained their ability to bind the ODC inhibitor antizyme, in most cases even more tightly than ODC
Mus musculus
4.1.1.17
additional information
antizyme inhibitors are homologs of ODC that have lost their decarboxylation activity but have retained their ability to bind the ODC inhibitor antizyme, in most cases even more tightly than ODC
Homo sapiens
4.1.1.17
additional information
antizyme inhibitors are homologs of ODC that have lost their decarboxylation activity but have retained their ability to bind the ODC inhibitor antizyme, in most cases even more tightly than ODC
Rattus norvegicus
4.1.1.17
additional information
antizyme inhibitors are homologs of ODC that have lost their decarboxylation activity but have retained their ability to bind the ODC inhibitor antizyme, in most cases even more tightly than ODC
Bos taurus
4.1.1.17
additional information
antizyme inhibitors are homologs of ODC that have lost their decarboxylation activity but have retained their ability to bind the ODC inhibitor antizyme, in most cases even more tightly than ODC
Neurospora crassa
4.1.1.17
additional information
antizyme inhibitors are homologs of ODC that have lost their decarboxylation activity but have retained their ability to bind the ODC inhibitor antizyme, in most cases even more tightly than ODC
Trypanosoma brucei
4.1.1.17
additional information
antizyme inhibitors are homologs of ODC that have lost their decarboxylation activity but have retained their ability to bind the ODC inhibitor antizyme, in most cases even more tightly than ODC
Dictyostelium discoideum
4.1.1.17
additional information
antizyme inhibitors are homologs of ODC that have lost their decarboxylation activity but have retained their ability to bind the ODC inhibitor antizyme, in most cases even more tightly than ODC
Canis lupus familiaris
4.1.1.17
additional information
antizyme inhibitors are homologs of ODC that have lost their decarboxylation activity but have retained their ability to bind the ODC inhibitor antizyme, in most cases even more tightly than ODC
Xenopus laevis
4.1.1.17
additional information
antizyme inhibitors are homologs of ODC that have lost their decarboxylation activity but have retained their ability to bind the ODC inhibitor antizyme, in most cases even more tightly than ODC
Caenorhabditis elegans
4.1.1.17
additional information
antizyme inhibitors are homologs of ODC that have lost their decarboxylation activity but have retained their ability to bind the ODC inhibitor antizyme, in most cases even more tightly than ODC
Meyerozyma guilliermondii
4.1.1.17
additional information
antizyme inhibitors are homologs of ODC that have lost their decarboxylation activity but have retained their ability to bind the ODC inhibitor antizyme, in most cases even more tightly than ODC
Aedes aegypti
4.1.1.17
additional information
antizyme inhibitors are homologs of ODC that have lost their decarboxylation activity but have retained their ability to bind the ODC inhibitor antizyme, in most cases even more tightly than ODC
Aspergillus fischeri
4.1.1.17
additional information
antizyme inhibitors are homologs of ODC that have lost their decarboxylation activity but have retained their ability to bind the ODC inhibitor antizyme, in most cases even more tightly than ODC
Aspergillus terreus
4.1.1.17
additional information
antizyme inhibitors are homologs of ODC that have lost their decarboxylation activity but have retained their ability to bind the ODC inhibitor antizyme, in most cases even more tightly than ODC
Fusarium oxysporum
4.1.1.17
additional information
antizyme inhibitors are homologs of ODC that have lost their decarboxylation activity but have retained their ability to bind the ODC inhibitor antizyme, in most cases even more tightly than ODC
Fusarium verticillioides
4.1.1.17
additional information
antizyme inhibitors are homologs of ODC that have lost their decarboxylation activity but have retained their ability to bind the ODC inhibitor antizyme, in most cases even more tightly than ODC
Aspergillus clavatus
4.1.1.17
additional information
antizyme inhibitors are homologs of ODC that have lost their decarboxylation activity but have retained their ability to bind the ODC inhibitor antizyme, in most cases even more tightly than ODC
Aspergillus fumigatus
4.1.1.17
additional information
antizyme inhibitors are homologs of ODC that have lost their decarboxylation activity but have retained their ability to bind the ODC inhibitor antizyme, in most cases even more tightly than ODC
Ciona intestinalis
4.1.1.17
additional information
antizyme inhibitors are homologs of ODC that have lost their decarboxylation activity but have retained their ability to bind the ODC inhibitor antizyme, in most cases even more tightly than ODC
Branchiostoma floridae
4.1.1.17
additional information
antizyme inhibitors are homologs of ODC that have lost their decarboxylation activity but have retained their ability to bind the ODC inhibitor antizyme, in most cases even more tightly than ODC
Botrytis cinerea
4.1.1.17
additional information
antizyme inhibitors are homologs of ODC that have lost their decarboxylation activity but have retained their ability to bind the ODC inhibitor antizyme, in most cases even more tightly than ODC
Coccidioides immitis
4.1.1.17
additional information
antizyme inhibitors are homologs of ODC that have lost their decarboxylation activity but have retained their ability to bind the ODC inhibitor antizyme, in most cases even more tightly than ODC
Anopheles gambiae
4.1.1.17
additional information
antizyme inhibitors are homologs of ODC that have lost their decarboxylation activity but have retained their ability to bind the ODC inhibitor antizyme, in most cases even more tightly than ODC
Caenorhabditis briggsae
4.1.1.17
additional information
antizyme inhibitors are homologs of ODC that have lost their decarboxylation activity but have retained their ability to bind the ODC inhibitor antizyme, in most cases even more tightly than ODC
Culex pipiens
4.1.1.17
additional information
antizyme inhibitors are homologs of ODC that have lost their decarboxylation activity but have retained their ability to bind the ODC inhibitor antizyme, in most cases even more tightly than ODC
Ancylostoma ceylanicum
4.1.1.17
additional information
antizyme inhibitors are homologs of ODC that have lost their decarboxylation activity but have retained their ability to bind the ODC inhibitor antizyme, in most cases even more tightly than ODC
Takifugu rubripes
4.1.1.17
additional information
antizyme inhibitors are homologs of ODC that have lost their decarboxylation activity but have retained their ability to bind the ODC inhibitor antizyme, in most cases even more tightly than ODC
Petromyzon marinus
4.1.1.17
additional information
antizyme inhibitors are homologs of ODC that have lost their decarboxylation activity but have retained their ability to bind the ODC inhibitor antizyme, in most cases even more tightly than ODC
Parastagonospora nodorum
4.1.1.17
additional information
antizyme inhibitors are homologs of ODC that have lost their decarboxylation activity but have retained their ability to bind the ODC inhibitor antizyme, in most cases even more tightly than ODC
Uncinocarpus reesii
4.1.1.17
additional information
antizyme inhibitors are homologs of ODC that have lost their decarboxylation activity but have retained their ability to bind the ODC inhibitor antizyme, in most cases even more tightly than ODC
Hydra vulgaris
4.1.1.17
additional information
antizyme inhibitors are homologs of ODC that have lost their decarboxylation activity but have retained their ability to bind the ODC inhibitor antizyme, in most cases even more tightly than ODC
Tetraodon nigroviridis
4.1.1.17
additional information
antizyme inhibitors are homologs of ODC that have lost their decarboxylation activity but have retained their ability to bind the ODC inhibitor antizyme, in most cases even more tightly than ODC
Gasterosteus aculeatus
4.1.1.17
additional information
antizyme inhibitors are homologs of ODC that have lost their decarboxylation activity but have retained their ability to bind the ODC inhibitor antizyme, in most cases even more tightly than ODC
Dugesia japonica
4.1.1.17
additional information
antizyme inhibitors are homologs of ODC that have lost their decarboxylation activity but have retained their ability to bind the ODC inhibitor antizyme, in most cases even more tightly than ODC
Anolis carolinensis
4.1.1.17
additional information
antizyme inhibitors are homologs of ODC that have lost their decarboxylation activity but have retained their ability to bind the ODC inhibitor antizyme, in most cases even more tightly than ODC
Schmidtea mediterranea
4.1.1.17
additional information
antizyme inhibitors are homologs of ODC that have lost their decarboxylation activity but have retained their ability to bind the ODC inhibitor antizyme, in most cases even more tightly than ODC
Nasonia vitripennis
Natural Substrates/ Products (Substrates)
EC Number
Natural Substrates
Organism
Commentary (Nat. Sub.)
Natural Products
Commentary (Nat. Pro.)
Organism (Nat. Pro.)
Reversibility
ID
4.1.1.17
L-ornithine
Gallus gallus
-
putrescine + CO2
-
-
?
4.1.1.17
L-ornithine
Drosophila melanogaster
-
putrescine + CO2
-
-
?
4.1.1.17
L-ornithine
Mus musculus
-
putrescine + CO2
-
-
?
4.1.1.17
L-ornithine
Homo sapiens
-
putrescine + CO2
-
-
?
4.1.1.17
L-ornithine
Rattus norvegicus
-
putrescine + CO2
-
-
?
4.1.1.17
L-ornithine
Bos taurus
-
putrescine + CO2
-
-
?
4.1.1.17
L-ornithine
Neurospora crassa
-
putrescine + CO2
-
-
?
4.1.1.17
L-ornithine
Trypanosoma brucei
-
putrescine + CO2
-
-
?
4.1.1.17
L-ornithine
Dictyostelium discoideum
-
putrescine + CO2
-
-
?
4.1.1.17
L-ornithine
Canis lupus familiaris
-
putrescine + CO2
-
-
?
4.1.1.17
L-ornithine
Xenopus laevis
-
putrescine + CO2
-
-
?
4.1.1.17
L-ornithine
Caenorhabditis elegans
-
putrescine + CO2
-
-
?
4.1.1.17
L-ornithine
Meyerozyma guilliermondii
-
putrescine + CO2
-
-
?
4.1.1.17
L-ornithine
Aedes aegypti
-
putrescine + CO2
-
-
?
4.1.1.17
L-ornithine
Aspergillus fischeri
-
putrescine + CO2
-
-
?
4.1.1.17
L-ornithine
Aspergillus terreus
-
putrescine + CO2
-
-
?
4.1.1.17
L-ornithine
Fusarium oxysporum
-
putrescine + CO2
-
-
?
4.1.1.17
L-ornithine
Fusarium verticillioides
-
putrescine + CO2
-
-
?
4.1.1.17
L-ornithine
Aspergillus clavatus
-
putrescine + CO2
-
-
?
4.1.1.17
L-ornithine
Aspergillus fumigatus
-
putrescine + CO2
-
-
?
4.1.1.17
L-ornithine
Ciona intestinalis
-
putrescine + CO2
-
-
?
4.1.1.17
L-ornithine
Branchiostoma floridae
-
putrescine + CO2
-
-
?
4.1.1.17
L-ornithine
Botrytis cinerea
-
putrescine + CO2
-
-
?
4.1.1.17
L-ornithine
Coccidioides immitis
-
putrescine + CO2
-
-
?
4.1.1.17
L-ornithine
Anopheles gambiae
-
putrescine + CO2
-
-
?
4.1.1.17
L-ornithine
Caenorhabditis briggsae
-
putrescine + CO2
-
-
?
4.1.1.17
L-ornithine
Culex pipiens
-
putrescine + CO2
-
-
?
4.1.1.17
L-ornithine
Ancylostoma ceylanicum
-
putrescine + CO2
-
-
?
4.1.1.17
L-ornithine
Takifugu rubripes
-
putrescine + CO2
-
-
?
4.1.1.17
L-ornithine
Petromyzon marinus
-
putrescine + CO2
-
-
?
4.1.1.17
L-ornithine
Parastagonospora nodorum
-
putrescine + CO2
-
-
?
4.1.1.17
L-ornithine
Uncinocarpus reesii
-
putrescine + CO2
-
-
?
4.1.1.17
L-ornithine
Hydra vulgaris
-
putrescine + CO2
-
-
?
4.1.1.17
L-ornithine
Tetraodon nigroviridis
-
putrescine + CO2
-
-
?
4.1.1.17
L-ornithine
Gasterosteus aculeatus
-
putrescine + CO2
-
-
?
4.1.1.17
L-ornithine
Dugesia japonica
-
putrescine + CO2
-
-
?
4.1.1.17
L-ornithine
Anolis carolinensis
-
putrescine + CO2
-
-
?
4.1.1.17
L-ornithine
Schmidtea mediterranea
-
putrescine + CO2
-
-
?
4.1.1.17
L-ornithine
Nasonia vitripennis
-
putrescine + CO2
-
-
?
Organism
EC Number
Organism
UniProt
Commentary
Textmining
4.1.1.17
Aedes aegypti
-
-
-
4.1.1.17
Ancylostoma ceylanicum
-
-
-
4.1.1.17
Anolis carolinensis
-
-
-
4.1.1.17
Anopheles gambiae
-
-
-
4.1.1.17
Aspergillus clavatus
-
-
-
4.1.1.17
Aspergillus fischeri
-
-
-
4.1.1.17
Aspergillus fumigatus
-
-
-
4.1.1.17
Aspergillus terreus
-
-
-
4.1.1.17
Bos taurus
-
-
-
4.1.1.17
Botrytis cinerea
-
-
-
4.1.1.17
Branchiostoma floridae
-
-
-
4.1.1.17
Caenorhabditis briggsae
-
-
-
4.1.1.17
Caenorhabditis elegans
-
-
-
4.1.1.17
Canis lupus familiaris
-
-
-
4.1.1.17
Ciona intestinalis
-
-
-
4.1.1.17
Coccidioides immitis
-
-
-
4.1.1.17
Culex pipiens
-
-
-
4.1.1.17
Dictyostelium discoideum
-
-
-
4.1.1.17
Drosophila melanogaster
-
-
-
4.1.1.17
Dugesia japonica
-
-
-
4.1.1.17
Fusarium oxysporum
-
-
-
4.1.1.17
Fusarium verticillioides
-
-
-
4.1.1.17
Gallus gallus
-
-
-
4.1.1.17
Gasterosteus aculeatus
-
-
-
4.1.1.17
Homo sapiens
-
-
-
4.1.1.17
Hydra vulgaris
-
-
-
4.1.1.17
Meyerozyma guilliermondii
-
-
-
4.1.1.17
Mus musculus
-
-
-
4.1.1.17
Nasonia vitripennis
-
-
-
4.1.1.17
Neurospora crassa
-
-
-
4.1.1.17
Parastagonospora nodorum
-
-
-
4.1.1.17
Petromyzon marinus
-
-
-
4.1.1.17
Rattus norvegicus
-
-
-
4.1.1.17
Schmidtea mediterranea
-
-
-
4.1.1.17
Takifugu rubripes
-
-
-
4.1.1.17
Tetraodon nigroviridis
-
-
-
4.1.1.17
Trypanosoma brucei
-
-
-
4.1.1.17
Uncinocarpus reesii
-
-
-
4.1.1.17
Xenopus laevis
-
-
-
Substrates and Products (Substrate)
EC Number
Substrates
Commentary Substrates
Literature (Substrates)
Organism
Products
Commentary (Products)
Literature (Products)
Organism (Products)
Reversibility
Substrate Product ID
4.1.1.17
L-ornithine
-
709568
Gallus gallus
putrescine + CO2
-
-
-
?
4.1.1.17
L-ornithine
-
709568
Drosophila melanogaster
putrescine + CO2
-
-
-
?
4.1.1.17
L-ornithine
-
709568
Mus musculus
putrescine + CO2
-
-
-
?
4.1.1.17
L-ornithine
-
709568
Homo sapiens
putrescine + CO2
-
-
-
?
4.1.1.17
L-ornithine
-
709568
Rattus norvegicus
putrescine + CO2
-
-
-
?
4.1.1.17
L-ornithine
-
709568
Bos taurus
putrescine + CO2
-
-
-
?
4.1.1.17
L-ornithine
-
709568
Neurospora crassa
putrescine + CO2
-
-
-
?
4.1.1.17
L-ornithine
-
709568
Trypanosoma brucei
putrescine + CO2
-
-
-
?
4.1.1.17
L-ornithine
-
709568
Dictyostelium discoideum
putrescine + CO2
-
-
-
?
4.1.1.17
L-ornithine
-
709568
Canis lupus familiaris
putrescine + CO2
-
-
-
?
4.1.1.17
L-ornithine
-
709568
Xenopus laevis
putrescine + CO2
-
-
-
?
4.1.1.17
L-ornithine
-
709568
Caenorhabditis elegans
putrescine + CO2
-
-
-
?
4.1.1.17
L-ornithine
-
709568
Meyerozyma guilliermondii
putrescine + CO2
-
-
-
?
4.1.1.17
L-ornithine
-
709568
Aedes aegypti
putrescine + CO2
-
-
-
?
4.1.1.17
L-ornithine
-
709568
Aspergillus fischeri
putrescine + CO2
-
-
-
?
4.1.1.17
L-ornithine
-
709568
Aspergillus terreus
putrescine + CO2
-
-
-
?
4.1.1.17
L-ornithine
-
709568
Fusarium oxysporum
putrescine + CO2
-
-
-
?
4.1.1.17
L-ornithine
-
709568
Fusarium verticillioides
putrescine + CO2
-
-
-
?
4.1.1.17
L-ornithine
-
709568
Aspergillus clavatus
putrescine + CO2
-
-
-
?
4.1.1.17
L-ornithine
-
709568
Aspergillus fumigatus
putrescine + CO2
-
-
-
?
4.1.1.17
L-ornithine
-
709568
Ciona intestinalis
putrescine + CO2
-
-
-
?
4.1.1.17
L-ornithine
-
709568
Branchiostoma floridae
putrescine + CO2
-
-
-
?
4.1.1.17
L-ornithine
-
709568
Botrytis cinerea
putrescine + CO2
-
-
-
?
4.1.1.17
L-ornithine
-
709568
Coccidioides immitis
putrescine + CO2
-
-
-
?
4.1.1.17
L-ornithine
-
709568
Anopheles gambiae
putrescine + CO2
-
-
-
?
4.1.1.17
L-ornithine
-
709568
Caenorhabditis briggsae
putrescine + CO2
-
-
-
?
4.1.1.17
L-ornithine
-
709568
Culex pipiens
putrescine + CO2
-
-
-
?
4.1.1.17
L-ornithine
-
709568
Ancylostoma ceylanicum
putrescine + CO2
-
-
-
?
4.1.1.17
L-ornithine
-
709568
Takifugu rubripes
putrescine + CO2
-
-
-
?
4.1.1.17
L-ornithine
-
709568
Petromyzon marinus
putrescine + CO2
-
-
-
?
4.1.1.17
L-ornithine
-
709568
Parastagonospora nodorum
putrescine + CO2
-
-
-
?
4.1.1.17
L-ornithine
-
709568
Uncinocarpus reesii
putrescine + CO2
-
-
-
?
4.1.1.17
L-ornithine
-
709568
Hydra vulgaris
putrescine + CO2
-
-
-
?
4.1.1.17
L-ornithine
-
709568
Tetraodon nigroviridis
putrescine + CO2
-
-
-
?
4.1.1.17
L-ornithine
-
709568
Gasterosteus aculeatus
putrescine + CO2
-
-
-
?
4.1.1.17
L-ornithine
-
709568
Dugesia japonica
putrescine + CO2
-
-
-
?
4.1.1.17
L-ornithine
-
709568
Anolis carolinensis
putrescine + CO2
-
-
-
?
4.1.1.17
L-ornithine
-
709568
Schmidtea mediterranea
putrescine + CO2
-
-
-
?
4.1.1.17
L-ornithine
-
709568
Nasonia vitripennis
putrescine + CO2
-
-
-
?
Synonyms
EC Number
Synonyms
Commentary
Organism
4.1.1.17
ODC
-
Gallus gallus
4.1.1.17
ODC
-
Drosophila melanogaster
4.1.1.17
ODC
-
Mus musculus
4.1.1.17
ODC
-
Homo sapiens
4.1.1.17
ODC
-
Rattus norvegicus
4.1.1.17
ODC
-
Bos taurus
4.1.1.17
ODC
-
Neurospora crassa
4.1.1.17
ODC
-
Trypanosoma brucei
4.1.1.17
ODC
-
Dictyostelium discoideum
4.1.1.17
ODC
-
Canis lupus familiaris
4.1.1.17
ODC
-
Xenopus laevis
4.1.1.17
ODC
-
Caenorhabditis elegans
4.1.1.17
ODC
-
Meyerozyma guilliermondii
4.1.1.17
ODC
-
Aedes aegypti
4.1.1.17
ODC
-
Aspergillus fischeri
4.1.1.17
ODC
-
Aspergillus terreus
4.1.1.17
ODC
-
Fusarium oxysporum
4.1.1.17
ODC
-
Fusarium verticillioides
4.1.1.17
ODC
-
Aspergillus clavatus
4.1.1.17
ODC
-
Aspergillus fumigatus
4.1.1.17
ODC
-
Ciona intestinalis
4.1.1.17
ODC
-
Branchiostoma floridae
4.1.1.17
ODC
-
Botrytis cinerea
4.1.1.17
ODC
-
Coccidioides immitis
4.1.1.17
ODC
-
Anopheles gambiae
4.1.1.17
ODC
-
Caenorhabditis briggsae
4.1.1.17
ODC
-
Culex pipiens
4.1.1.17
ODC
-
Ancylostoma ceylanicum
4.1.1.17
ODC
-
Takifugu rubripes
4.1.1.17
ODC
-
Petromyzon marinus
4.1.1.17
ODC
-
Parastagonospora nodorum
4.1.1.17
ODC
-
Uncinocarpus reesii
4.1.1.17
ODC
-
Hydra vulgaris
4.1.1.17
ODC
-
Tetraodon nigroviridis
4.1.1.17
ODC
-
Gasterosteus aculeatus
4.1.1.17
ODC
-
Dugesia japonica
4.1.1.17
ODC
-
Anolis carolinensis
4.1.1.17
ODC
-
Schmidtea mediterranea
4.1.1.17
ODC
-
Nasonia vitripennis
Cofactor
EC Number
Cofactor
Commentary
Organism
Structure
4.1.1.17
pyridoxal 5'-phosphate
dependent on
Gallus gallus
4.1.1.17
pyridoxal 5'-phosphate
dependent on
Drosophila melanogaster
4.1.1.17
pyridoxal 5'-phosphate
dependent on
Mus musculus
4.1.1.17
pyridoxal 5'-phosphate
dependent on
Homo sapiens
4.1.1.17
pyridoxal 5'-phosphate
dependent on
Rattus norvegicus
4.1.1.17
pyridoxal 5'-phosphate
dependent on
Bos taurus
4.1.1.17
pyridoxal 5'-phosphate
dependent on
Neurospora crassa
4.1.1.17
pyridoxal 5'-phosphate
dependent on
Trypanosoma brucei
4.1.1.17
pyridoxal 5'-phosphate
dependent on
Dictyostelium discoideum
4.1.1.17
pyridoxal 5'-phosphate
dependent on
Canis lupus familiaris
4.1.1.17
pyridoxal 5'-phosphate
dependent on
Xenopus laevis
4.1.1.17
pyridoxal 5'-phosphate
dependent on
Caenorhabditis elegans
4.1.1.17
pyridoxal 5'-phosphate
dependent on
Meyerozyma guilliermondii
4.1.1.17
pyridoxal 5'-phosphate
dependent on
Aedes aegypti
4.1.1.17
pyridoxal 5'-phosphate
dependent on
Aspergillus fischeri
4.1.1.17
pyridoxal 5'-phosphate
dependent on
Aspergillus terreus
4.1.1.17
pyridoxal 5'-phosphate
dependent on
Fusarium oxysporum
4.1.1.17
pyridoxal 5'-phosphate
dependent on
Fusarium verticillioides
4.1.1.17
pyridoxal 5'-phosphate
dependent on
Aspergillus clavatus
4.1.1.17
pyridoxal 5'-phosphate
dependent on
Aspergillus fumigatus
4.1.1.17
pyridoxal 5'-phosphate
dependent on
Ciona intestinalis
4.1.1.17
pyridoxal 5'-phosphate
dependent on
Branchiostoma floridae
4.1.1.17
pyridoxal 5'-phosphate
dependent on
Botrytis cinerea
4.1.1.17
pyridoxal 5'-phosphate
dependent on
Coccidioides immitis
4.1.1.17
pyridoxal 5'-phosphate
dependent on
Anopheles gambiae
4.1.1.17
pyridoxal 5'-phosphate
dependent on
Caenorhabditis briggsae
4.1.1.17
pyridoxal 5'-phosphate
dependent on
Culex pipiens
4.1.1.17
pyridoxal 5'-phosphate
dependent on
Ancylostoma ceylanicum
4.1.1.17
pyridoxal 5'-phosphate
dependent on
Takifugu rubripes
4.1.1.17
pyridoxal 5'-phosphate
dependent on
Petromyzon marinus
4.1.1.17
pyridoxal 5'-phosphate
dependent on
Parastagonospora nodorum
4.1.1.17
pyridoxal 5'-phosphate
dependent on
Uncinocarpus reesii
4.1.1.17
pyridoxal 5'-phosphate
dependent on
Hydra vulgaris
4.1.1.17
pyridoxal 5'-phosphate
dependent on
Tetraodon nigroviridis
4.1.1.17
pyridoxal 5'-phosphate
dependent on
Gasterosteus aculeatus
4.1.1.17
pyridoxal 5'-phosphate
dependent on
Dugesia japonica
4.1.1.17
pyridoxal 5'-phosphate
dependent on
Anolis carolinensis
4.1.1.17
pyridoxal 5'-phosphate
dependent on
Schmidtea mediterranea
4.1.1.17
pyridoxal 5'-phosphate
dependent on
Nasonia vitripennis
Activating Compound (protein specific)
EC Number
Activating Compound
Commentary
Organism
Structure
4.1.1.17
additional information
antizyme inhibitors are homologs of ODC that have lost their decarboxylation activity but have retained their ability to bind the ODC inhibitor antizyme, in most cases even more tightly than ODC
Gallus gallus
4.1.1.17
additional information
antizyme inhibitors are homologs of ODC that have lost their decarboxylation activity but have retained their ability to bind the ODC inhibitor antizyme, in most cases even more tightly than ODC
Drosophila melanogaster
4.1.1.17
additional information
antizyme inhibitors are homologs of ODC that have lost their decarboxylation activity but have retained their ability to bind the ODC inhibitor antizyme, in most cases even more tightly than ODC
Mus musculus
4.1.1.17
additional information
antizyme inhibitors are homologs of ODC that have lost their decarboxylation activity but have retained their ability to bind the ODC inhibitor antizyme, in most cases even more tightly than ODC
Homo sapiens
4.1.1.17
additional information
antizyme inhibitors are homologs of ODC that have lost their decarboxylation activity but have retained their ability to bind the ODC inhibitor antizyme, in most cases even more tightly than ODC
Rattus norvegicus
4.1.1.17
additional information
antizyme inhibitors are homologs of ODC that have lost their decarboxylation activity but have retained their ability to bind the ODC inhibitor antizyme, in most cases even more tightly than ODC
Bos taurus
4.1.1.17
additional information
antizyme inhibitors are homologs of ODC that have lost their decarboxylation activity but have retained their ability to bind the ODC inhibitor antizyme, in most cases even more tightly than ODC
Neurospora crassa
4.1.1.17
additional information
antizyme inhibitors are homologs of ODC that have lost their decarboxylation activity but have retained their ability to bind the ODC inhibitor antizyme, in most cases even more tightly than ODC
Trypanosoma brucei
4.1.1.17
additional information
antizyme inhibitors are homologs of ODC that have lost their decarboxylation activity but have retained their ability to bind the ODC inhibitor antizyme, in most cases even more tightly than ODC
Dictyostelium discoideum
4.1.1.17
additional information
antizyme inhibitors are homologs of ODC that have lost their decarboxylation activity but have retained their ability to bind the ODC inhibitor antizyme, in most cases even more tightly than ODC
Canis lupus familiaris
4.1.1.17
additional information
antizyme inhibitors are homologs of ODC that have lost their decarboxylation activity but have retained their ability to bind the ODC inhibitor antizyme, in most cases even more tightly than ODC
Xenopus laevis
4.1.1.17
additional information
antizyme inhibitors are homologs of ODC that have lost their decarboxylation activity but have retained their ability to bind the ODC inhibitor antizyme, in most cases even more tightly than ODC
Caenorhabditis elegans
4.1.1.17
additional information
antizyme inhibitors are homologs of ODC that have lost their decarboxylation activity but have retained their ability to bind the ODC inhibitor antizyme, in most cases even more tightly than ODC
Meyerozyma guilliermondii
4.1.1.17
additional information
antizyme inhibitors are homologs of ODC that have lost their decarboxylation activity but have retained their ability to bind the ODC inhibitor antizyme, in most cases even more tightly than ODC
Aedes aegypti
4.1.1.17
additional information
antizyme inhibitors are homologs of ODC that have lost their decarboxylation activity but have retained their ability to bind the ODC inhibitor antizyme, in most cases even more tightly than ODC
Aspergillus fischeri
4.1.1.17
additional information
antizyme inhibitors are homologs of ODC that have lost their decarboxylation activity but have retained their ability to bind the ODC inhibitor antizyme, in most cases even more tightly than ODC
Aspergillus terreus
4.1.1.17
additional information
antizyme inhibitors are homologs of ODC that have lost their decarboxylation activity but have retained their ability to bind the ODC inhibitor antizyme, in most cases even more tightly than ODC
Fusarium oxysporum
4.1.1.17
additional information
antizyme inhibitors are homologs of ODC that have lost their decarboxylation activity but have retained their ability to bind the ODC inhibitor antizyme, in most cases even more tightly than ODC
Fusarium verticillioides
4.1.1.17
additional information
antizyme inhibitors are homologs of ODC that have lost their decarboxylation activity but have retained their ability to bind the ODC inhibitor antizyme, in most cases even more tightly than ODC
Aspergillus clavatus
4.1.1.17
additional information
antizyme inhibitors are homologs of ODC that have lost their decarboxylation activity but have retained their ability to bind the ODC inhibitor antizyme, in most cases even more tightly than ODC
Aspergillus fumigatus
4.1.1.17
additional information
antizyme inhibitors are homologs of ODC that have lost their decarboxylation activity but have retained their ability to bind the ODC inhibitor antizyme, in most cases even more tightly than ODC
Ciona intestinalis
4.1.1.17
additional information
antizyme inhibitors are homologs of ODC that have lost their decarboxylation activity but have retained their ability to bind the ODC inhibitor antizyme, in most cases even more tightly than ODC
Branchiostoma floridae
4.1.1.17
additional information
antizyme inhibitors are homologs of ODC that have lost their decarboxylation activity but have retained their ability to bind the ODC inhibitor antizyme, in most cases even more tightly than ODC
Botrytis cinerea
4.1.1.17
additional information
antizyme inhibitors are homologs of ODC that have lost their decarboxylation activity but have retained their ability to bind the ODC inhibitor antizyme, in most cases even more tightly than ODC
Coccidioides immitis
4.1.1.17
additional information
antizyme inhibitors are homologs of ODC that have lost their decarboxylation activity but have retained their ability to bind the ODC inhibitor antizyme, in most cases even more tightly than ODC
Anopheles gambiae
4.1.1.17
additional information
antizyme inhibitors are homologs of ODC that have lost their decarboxylation activity but have retained their ability to bind the ODC inhibitor antizyme, in most cases even more tightly than ODC
Caenorhabditis briggsae
4.1.1.17
additional information
antizyme inhibitors are homologs of ODC that have lost their decarboxylation activity but have retained their ability to bind the ODC inhibitor antizyme, in most cases even more tightly than ODC
Culex pipiens
4.1.1.17
additional information
antizyme inhibitors are homologs of ODC that have lost their decarboxylation activity but have retained their ability to bind the ODC inhibitor antizyme, in most cases even more tightly than ODC
Ancylostoma ceylanicum
4.1.1.17
additional information
antizyme inhibitors are homologs of ODC that have lost their decarboxylation activity but have retained their ability to bind the ODC inhibitor antizyme, in most cases even more tightly than ODC
Takifugu rubripes
4.1.1.17
additional information
antizyme inhibitors are homologs of ODC that have lost their decarboxylation activity but have retained their ability to bind the ODC inhibitor antizyme, in most cases even more tightly than ODC
Petromyzon marinus
4.1.1.17
additional information
antizyme inhibitors are homologs of ODC that have lost their decarboxylation activity but have retained their ability to bind the ODC inhibitor antizyme, in most cases even more tightly than ODC
Parastagonospora nodorum
4.1.1.17
additional information
antizyme inhibitors are homologs of ODC that have lost their decarboxylation activity but have retained their ability to bind the ODC inhibitor antizyme, in most cases even more tightly than ODC
Uncinocarpus reesii
4.1.1.17
additional information
antizyme inhibitors are homologs of ODC that have lost their decarboxylation activity but have retained their ability to bind the ODC inhibitor antizyme, in most cases even more tightly than ODC
Hydra vulgaris
4.1.1.17
additional information
antizyme inhibitors are homologs of ODC that have lost their decarboxylation activity but have retained their ability to bind the ODC inhibitor antizyme, in most cases even more tightly than ODC
Tetraodon nigroviridis
4.1.1.17
additional information
antizyme inhibitors are homologs of ODC that have lost their decarboxylation activity but have retained their ability to bind the ODC inhibitor antizyme, in most cases even more tightly than ODC
Gasterosteus aculeatus
4.1.1.17
additional information
antizyme inhibitors are homologs of ODC that have lost their decarboxylation activity but have retained their ability to bind the ODC inhibitor antizyme, in most cases even more tightly than ODC
Dugesia japonica
4.1.1.17
additional information
antizyme inhibitors are homologs of ODC that have lost their decarboxylation activity but have retained their ability to bind the ODC inhibitor antizyme, in most cases even more tightly than ODC
Anolis carolinensis
4.1.1.17
additional information
antizyme inhibitors are homologs of ODC that have lost their decarboxylation activity but have retained their ability to bind the ODC inhibitor antizyme, in most cases even more tightly than ODC
Schmidtea mediterranea
4.1.1.17
additional information
antizyme inhibitors are homologs of ODC that have lost their decarboxylation activity but have retained their ability to bind the ODC inhibitor antizyme, in most cases even more tightly than ODC
Nasonia vitripennis
Cofactor (protein specific)
EC Number
Cofactor
Commentary
Organism
Structure
4.1.1.17
pyridoxal 5'-phosphate
dependent on
Gallus gallus
4.1.1.17
pyridoxal 5'-phosphate
dependent on
Drosophila melanogaster
4.1.1.17
pyridoxal 5'-phosphate
dependent on
Mus musculus
4.1.1.17
pyridoxal 5'-phosphate
dependent on
Homo sapiens
4.1.1.17
pyridoxal 5'-phosphate
dependent on
Rattus norvegicus
4.1.1.17
pyridoxal 5'-phosphate
dependent on
Bos taurus
4.1.1.17
pyridoxal 5'-phosphate
dependent on
Neurospora crassa
4.1.1.17
pyridoxal 5'-phosphate
dependent on
Trypanosoma brucei
4.1.1.17
pyridoxal 5'-phosphate
dependent on
Dictyostelium discoideum
4.1.1.17
pyridoxal 5'-phosphate
dependent on
Canis lupus familiaris
4.1.1.17
pyridoxal 5'-phosphate
dependent on
Xenopus laevis
4.1.1.17
pyridoxal 5'-phosphate
dependent on
Caenorhabditis elegans
4.1.1.17
pyridoxal 5'-phosphate
dependent on
Meyerozyma guilliermondii
4.1.1.17
pyridoxal 5'-phosphate
dependent on
Aedes aegypti
4.1.1.17
pyridoxal 5'-phosphate
dependent on
Aspergillus fischeri
4.1.1.17
pyridoxal 5'-phosphate
dependent on
Aspergillus terreus
4.1.1.17
pyridoxal 5'-phosphate
dependent on
Fusarium oxysporum
4.1.1.17
pyridoxal 5'-phosphate
dependent on
Fusarium verticillioides
4.1.1.17
pyridoxal 5'-phosphate
dependent on
Aspergillus clavatus
4.1.1.17
pyridoxal 5'-phosphate
dependent on
Aspergillus fumigatus
4.1.1.17
pyridoxal 5'-phosphate
dependent on
Ciona intestinalis
4.1.1.17
pyridoxal 5'-phosphate
dependent on
Branchiostoma floridae
4.1.1.17
pyridoxal 5'-phosphate
dependent on
Botrytis cinerea
4.1.1.17
pyridoxal 5'-phosphate
dependent on
Coccidioides immitis
4.1.1.17
pyridoxal 5'-phosphate
dependent on
Anopheles gambiae
4.1.1.17
pyridoxal 5'-phosphate
dependent on
Caenorhabditis briggsae
4.1.1.17
pyridoxal 5'-phosphate
dependent on
Culex pipiens
4.1.1.17
pyridoxal 5'-phosphate
dependent on
Ancylostoma ceylanicum
4.1.1.17
pyridoxal 5'-phosphate
dependent on
Takifugu rubripes
4.1.1.17
pyridoxal 5'-phosphate
dependent on
Petromyzon marinus
4.1.1.17
pyridoxal 5'-phosphate
dependent on
Parastagonospora nodorum
4.1.1.17
pyridoxal 5'-phosphate
dependent on
Uncinocarpus reesii
4.1.1.17
pyridoxal 5'-phosphate
dependent on
Hydra vulgaris
4.1.1.17
pyridoxal 5'-phosphate
dependent on
Tetraodon nigroviridis
4.1.1.17
pyridoxal 5'-phosphate
dependent on
Gasterosteus aculeatus
4.1.1.17
pyridoxal 5'-phosphate
dependent on
Dugesia japonica
4.1.1.17
pyridoxal 5'-phosphate
dependent on
Anolis carolinensis
4.1.1.17
pyridoxal 5'-phosphate
dependent on
Schmidtea mediterranea
4.1.1.17
pyridoxal 5'-phosphate
dependent on
Nasonia vitripennis
Natural Substrates/ Products (Substrates) (protein specific)
EC Number
Natural Substrates
Organism
Commentary (Nat. Sub.)
Natural Products
Commentary (Nat. Pro.)
Organism (Nat. Pro.)
Reversibility
ID
4.1.1.17
L-ornithine
Gallus gallus
-
putrescine + CO2
-
-
?
4.1.1.17
L-ornithine
Drosophila melanogaster
-
putrescine + CO2
-
-
?
4.1.1.17
L-ornithine
Mus musculus
-
putrescine + CO2
-
-
?
4.1.1.17
L-ornithine
Homo sapiens
-
putrescine + CO2
-
-
?
4.1.1.17
L-ornithine
Rattus norvegicus
-
putrescine + CO2
-
-
?
4.1.1.17
L-ornithine
Bos taurus
-
putrescine + CO2
-
-
?
4.1.1.17
L-ornithine
Neurospora crassa
-
putrescine + CO2
-
-
?
4.1.1.17
L-ornithine
Trypanosoma brucei
-
putrescine + CO2
-
-
?
4.1.1.17
L-ornithine
Dictyostelium discoideum
-
putrescine + CO2
-
-
?
4.1.1.17
L-ornithine
Canis lupus familiaris
-
putrescine + CO2
-
-
?
4.1.1.17
L-ornithine
Xenopus laevis
-
putrescine + CO2
-
-
?
4.1.1.17
L-ornithine
Caenorhabditis elegans
-
putrescine + CO2
-
-
?
4.1.1.17
L-ornithine
Meyerozyma guilliermondii
-
putrescine + CO2
-
-
?
4.1.1.17
L-ornithine
Aedes aegypti
-
putrescine + CO2
-
-
?
4.1.1.17
L-ornithine
Aspergillus fischeri
-
putrescine + CO2
-
-
?
4.1.1.17
L-ornithine
Aspergillus terreus
-
putrescine + CO2
-
-
?
4.1.1.17
L-ornithine
Fusarium oxysporum
-
putrescine + CO2
-
-
?
4.1.1.17
L-ornithine
Fusarium verticillioides
-
putrescine + CO2
-
-
?
4.1.1.17
L-ornithine
Aspergillus clavatus
-
putrescine + CO2
-
-
?
4.1.1.17
L-ornithine
Aspergillus fumigatus
-
putrescine + CO2
-
-
?
4.1.1.17
L-ornithine
Ciona intestinalis
-
putrescine + CO2
-
-
?
4.1.1.17
L-ornithine
Branchiostoma floridae
-
putrescine + CO2
-
-
?
4.1.1.17
L-ornithine
Botrytis cinerea
-
putrescine + CO2
-
-
?
4.1.1.17
L-ornithine
Coccidioides immitis
-
putrescine + CO2
-
-
?
4.1.1.17
L-ornithine
Anopheles gambiae
-
putrescine + CO2
-
-
?
4.1.1.17
L-ornithine
Caenorhabditis briggsae
-
putrescine + CO2
-
-
?
4.1.1.17
L-ornithine
Culex pipiens
-
putrescine + CO2
-
-
?
4.1.1.17
L-ornithine
Ancylostoma ceylanicum
-
putrescine + CO2
-
-
?
4.1.1.17
L-ornithine
Takifugu rubripes
-
putrescine + CO2
-
-
?
4.1.1.17
L-ornithine
Petromyzon marinus
-
putrescine + CO2
-
-
?
4.1.1.17
L-ornithine
Parastagonospora nodorum
-
putrescine + CO2
-
-
?
4.1.1.17
L-ornithine
Uncinocarpus reesii
-
putrescine + CO2
-
-
?
4.1.1.17
L-ornithine
Hydra vulgaris
-
putrescine + CO2
-
-
?
4.1.1.17
L-ornithine
Tetraodon nigroviridis
-
putrescine + CO2
-
-
?
4.1.1.17
L-ornithine
Gasterosteus aculeatus
-
putrescine + CO2
-
-
?
4.1.1.17
L-ornithine
Dugesia japonica
-
putrescine + CO2
-
-
?
4.1.1.17
L-ornithine
Anolis carolinensis
-
putrescine + CO2
-
-
?
4.1.1.17
L-ornithine
Schmidtea mediterranea
-
putrescine + CO2
-
-
?
4.1.1.17
L-ornithine
Nasonia vitripennis
-
putrescine + CO2
-
-
?
Substrates and Products (Substrate) (protein specific)
EC Number
Substrates
Commentary Substrates
Literature (Substrates)
Organism
Products
Commentary (Products)
Literature (Products)
Organism (Products)
Reversibility
ID
4.1.1.17
L-ornithine
-
709568
Gallus gallus
putrescine + CO2
-
-
-
?
4.1.1.17
L-ornithine
-
709568
Drosophila melanogaster
putrescine + CO2
-
-
-
?
4.1.1.17
L-ornithine
-
709568
Mus musculus
putrescine + CO2
-
-
-
?
4.1.1.17
L-ornithine
-
709568
Homo sapiens
putrescine + CO2
-
-
-
?
4.1.1.17
L-ornithine
-
709568
Rattus norvegicus
putrescine + CO2
-
-
-
?
4.1.1.17
L-ornithine
-
709568
Bos taurus
putrescine + CO2
-
-
-
?
4.1.1.17
L-ornithine
-
709568
Neurospora crassa
putrescine + CO2
-
-
-
?
4.1.1.17
L-ornithine
-
709568
Trypanosoma brucei
putrescine + CO2
-
-
-
?
4.1.1.17
L-ornithine
-
709568
Dictyostelium discoideum
putrescine + CO2
-
-
-
?
4.1.1.17
L-ornithine
-
709568
Canis lupus familiaris
putrescine + CO2
-
-
-
?
4.1.1.17
L-ornithine
-
709568
Xenopus laevis
putrescine + CO2
-
-
-
?
4.1.1.17
L-ornithine
-
709568
Caenorhabditis elegans
putrescine + CO2
-
-
-
?
4.1.1.17
L-ornithine
-
709568
Meyerozyma guilliermondii
putrescine + CO2
-
-
-
?
4.1.1.17
L-ornithine
-
709568
Aedes aegypti
putrescine + CO2
-
-
-
?
4.1.1.17
L-ornithine
-
709568
Aspergillus fischeri
putrescine + CO2
-
-
-
?
4.1.1.17
L-ornithine
-
709568
Aspergillus terreus
putrescine + CO2
-
-
-
?
4.1.1.17
L-ornithine
-
709568
Fusarium oxysporum
putrescine + CO2
-
-
-
?
4.1.1.17
L-ornithine
-
709568
Fusarium verticillioides
putrescine + CO2
-
-
-
?
4.1.1.17
L-ornithine
-
709568
Aspergillus clavatus
putrescine + CO2
-
-
-
?
4.1.1.17
L-ornithine
-
709568
Aspergillus fumigatus
putrescine + CO2
-
-
-
?
4.1.1.17
L-ornithine
-
709568
Ciona intestinalis
putrescine + CO2
-
-
-
?
4.1.1.17
L-ornithine
-
709568
Branchiostoma floridae
putrescine + CO2
-
-
-
?
4.1.1.17
L-ornithine
-
709568
Botrytis cinerea
putrescine + CO2
-
-
-
?
4.1.1.17
L-ornithine
-
709568
Coccidioides immitis
putrescine + CO2
-
-
-
?
4.1.1.17
L-ornithine
-
709568
Anopheles gambiae
putrescine + CO2
-
-
-
?
4.1.1.17
L-ornithine
-
709568
Caenorhabditis briggsae
putrescine + CO2
-
-
-
?
4.1.1.17
L-ornithine
-
709568
Culex pipiens
putrescine + CO2
-
-
-
?
4.1.1.17
L-ornithine
-
709568
Ancylostoma ceylanicum
putrescine + CO2
-
-
-
?
4.1.1.17
L-ornithine
-
709568
Takifugu rubripes
putrescine + CO2
-
-
-
?
4.1.1.17
L-ornithine
-
709568
Petromyzon marinus
putrescine + CO2
-
-
-
?
4.1.1.17
L-ornithine
-
709568
Parastagonospora nodorum
putrescine + CO2
-
-
-
?
4.1.1.17
L-ornithine
-
709568
Uncinocarpus reesii
putrescine + CO2
-
-
-
?
4.1.1.17
L-ornithine
-
709568
Hydra vulgaris
putrescine + CO2
-
-
-
?
4.1.1.17
L-ornithine
-
709568
Tetraodon nigroviridis
putrescine + CO2
-
-
-
?
4.1.1.17
L-ornithine
-
709568
Gasterosteus aculeatus
putrescine + CO2
-
-
-
?
4.1.1.17
L-ornithine
-
709568
Dugesia japonica
putrescine + CO2
-
-
-
?
4.1.1.17
L-ornithine
-
709568
Anolis carolinensis
putrescine + CO2
-
-
-
?
4.1.1.17
L-ornithine
-
709568
Schmidtea mediterranea
putrescine + CO2
-
-
-
?
4.1.1.17
L-ornithine
-
709568
Nasonia vitripennis
putrescine + CO2
-
-
-
?