Any feedback?
Please rate this page
(literature.php)
(0/150)

BRENDA support

Literature summary extracted from

  • Wei, C.C.; Hase, N.; Inoue, Y.; Bradley, E.W.; Yahiro, E.; Li, M.; Naqvi, N.; Powell, P.C.; Shi, K.; Takahashi, Y.; Saku, K.; Urata, H.; Dellitalia, L.J.; Husain, A.
    Mast cell chymase limits the cardiac efficacy of Ang I-converting enzyme inhibitor therapy in rodents (2010), J. Clin. Invest., 120, 1229-1239.
    View publication on PubMedView publication on EuropePMC

Localization

EC Number Localization Comment Organism GeneOntology No. Textmining
3.4.21.39 cytoplasmic vesicle
-
 Mus musculus 31410
-

Organism

EC Number Organism UniProt Comment Textmining
3.4.21.39 Mus musculus
-
-
-

Source Tissue

EC Number Source Tissue Comment Organism Textmining
3.4.21.39 heart interstitial fluid from left ventricle Mus musculus
-
3.4.21.39 mast cell
-
 Mus musculus
-

Substrates and Products (Substrate)

EC Number Substrates Comment Substrates Organism Products Comment (Products) Rev. Reac.
3.4.21.39 angiotensin I + H2O
-
 Mus musculus angiotensin II + ?
-
 ?

Synonyms

EC Number Synonyms Comment Organism
3.4.21.39 mast cell chymase
-
 Mus musculus

Expression

EC Number Organism Comment Expression
3.4.21.39 Mus musculus chronic angiotensin I-converting enzyme inhibition causes a marked bradykinin/B2 receptor-mediated increase in left ventricle interstitial fluid chymase activity up

General Information

EC Number General Information Comment Organism
3.4.21.39 malfunction chymase inhibition improves LV function and decreases adverse cardiac remodeling after myocardial infarction Mus musculus