EC Number | Metals/Ions | Comment | Organism | Structure |
---|---|---|---|---|
2.7.11.18 | Ca2+ | required for activity | Mus musculus |
EC Number | Organism | UniProt | Comment | Textmining |
---|---|---|---|---|
2.7.11.18 | Mus musculus | - |
- |
- |
EC Number | Source Tissue | Comment | Organism | Textmining |
---|---|---|---|---|
2.7.11.18 | bronchial smooth muscle cell | - |
Mus musculus | - |
2.7.11.18 | tracheal smooth muscle cell | - |
Mus musculus | - |
EC Number | Substrates | Comment Substrates | Organism | Products | Comment (Products) | Rev. | Reac. |
---|---|---|---|---|---|---|---|
2.7.11.18 | ATP + myosin regulatory light chain | - |
Mus musculus | ADP + myosin regulatory light chain phosphate | - |
? |
EC Number | Synonyms | Comment | Organism |
---|---|---|---|
2.7.11.18 | MLCK | - |
Mus musculus |
2.7.11.18 | myosin light chain kinase | - |
Mus musculus |
EC Number | Cofactor | Comment | Organism | Structure |
---|---|---|---|---|
2.7.11.18 | ATP | - |
Mus musculus | |
2.7.11.18 | Calmodulin | - |
Mus musculus |
EC Number | General Information | Comment | Organism |
---|---|---|---|
2.7.11.18 | malfunction | MLCK-deficient mice lack bronchial constrictions in normal and asthmatic airways, while the asthmatic inflammation response is not affected | Mus musculus |
2.7.11.18 | physiological function | myosin light chain kinase acts as a central participant in the contractile signaling module of tonic smooth muscle | Mus musculus |