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Literature summary extracted from

  • Llamas, A.; Otte, T.; Multhaup, G.; Mendel, R.R.; Schwarz, G.
    The Mechanism of nucleotide-assisted molybdenum insertion into molybdopterin. A novel route toward metal cofactor assembly (2006), J. Biol. Chem., 281, 18343-18350.
    View publication on PubMed

Inhibitors

EC Number Inhibitors Comment Organism Structure
2.10.1.1 sulfate less efficient inhibition than tungstate Arabidopsis thaliana
2.10.1.1 tungstate 20fold excess to molybdate Arabidopsis thaliana

Metals/Ions

EC Number Metals/Ions Comment Organism Structure
2.10.1.1 Mg2+ required Arabidopsis thaliana
2.10.1.1 Mn2+ required, less efficient Arabidopsis thaliana
2.10.1.1 Ni2+ required, less efficient Arabidopsis thaliana
2.10.1.1 Zn2+ required Arabidopsis thaliana

Natural Substrates/ Products (Substrates)

EC Number Natural Substrates Organism Comment (Nat. Sub.) Natural Products Comment (Nat. Pro.) Rev. Reac.
2.10.1.1 adenylyl-molybdopterin + molybdate + 4 H+ Arabidopsis thaliana
-
 molybdenum cofactor + AMP + H2O
-
 ?

Organism

EC Number Organism UniProt Comment Textmining
2.10.1.1 Arabidopsis thaliana Q39054 domain E
-

Substrates and Products (Substrate)

EC Number Substrates Comment Substrates Organism Products Comment (Products) Rev. Reac.
2.10.1.1 adenylyl-molybdopterin + molybdate + 4 H+
-
 Arabidopsis thaliana molybdenum cofactor + AMP + H2O
-
 ?

Synonyms

EC Number Synonyms Comment Organism
2.10.1.1 Cnx1 N-terminal E-domain, gene name Arabidopsis thaliana

Turnover Number [1/s]

EC Number Turnover Number Minimum [1/s] Turnover Number Maximum [1/s] Substrate Comment Organism Structure
2.10.1.1 0.25
-
 molybdate in presence of Mg2+, pH 7.2, temperature not specified in the publication Arabidopsis thaliana
2.10.1.1 2.5
-
 molybdate in presence of Zn2+, pH 7.2, temperature not specified in the publication Arabidopsis thaliana

General Information

EC Number General Information Comment Organism
2.10.1.1 metabolism molybdenum cofactor biosynthesis Arabidopsis thaliana