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Literature summary extracted from

  • Nakahara, T.; Sano, A.; Yamaguchi, H.; Sugimoto, K.; Chikata, H.; Kinoshita, E.; Uchida, R.
    Antihypertensive effect of peptide-enriched soy sauce-like seasoning and identification of its angiotensin I-converting enzyme inhibitory substances (2010), J. Agric. Food Chem., 58, 821-827.
    View publication on PubMed

Inhibitors

EC Number Inhibitors Comment Organism Structure
3.4.15.1 Ala-Ile
-
 Rattus norvegicus
3.4.15.1 Ala-Phe
-
 Rattus norvegicus
3.4.15.1 Ala-Trp
-
 Rattus norvegicus
3.4.15.1 Ala-Tyr
-
 Rattus norvegicus
3.4.15.1 Gly-Trp
-
 Rattus norvegicus
3.4.15.1 Gly-Tyr
-
 Rattus norvegicus
3.4.15.1 additional information 2.7fold peptide-enriched soy sauce-like seasoning, termed Fermented Soybean Seasoning, FSS, shows ACE inhibitory activity with an IC50 of 0.454 mg/ml, fermentation method, overview. FSS shows antihypertensive effects, overview Rattus norvegicus
3.4.15.1 nicotianamine
-
 Rattus norvegicus
3.4.15.1 Ser-Tyr
-
 Rattus norvegicus
3.4.15.1 Val-Gly
-
 Rattus norvegicus
3.4.15.1 Val-Pro
-
 Rattus norvegicus

Organism

EC Number Organism UniProt Comment Textmining
3.4.15.1 Rattus norvegicus
-
-
-

Synonyms

EC Number Synonyms Comment Organism
3.4.15.1 ACE
-
 Rattus norvegicus
3.4.15.1 angiotensin I-converting enzyme
-
 Rattus norvegicus

IC50 Value

EC Number IC50 Value IC50 Value Maximum Comment Organism Inhibitor Structure
3.4.15.1 additional information
-
 IC50 values of nicotianamine, Val-Gly, Gly-Tyr, Ser-Tyr, Ala-Tyr, Ala-Ile, Val-Pro, Ala-Phe, Gly-Trp, and Ala-Trp are 0.442 mg/ml, 0.172 mg/ml, 0.132 mg/ml, 0.132 mg/ml, 0.132 mg/ml, 0.132 mg/ml, 0.172 mg/ml, 0.224 mg/ml, 0.199 mg/ml, and 0.199 mg/ml Rattus norvegicus additional information
3.4.15.1 0.132
-
-
 Rattus norvegicus Gly-Tyr
3.4.15.1 0.132
-
-
 Rattus norvegicus Ala-Tyr
3.4.15.1 0.132
-
-
 Rattus norvegicus Ser-Tyr
3.4.15.1 0.132
-
-
 Rattus norvegicus Ala-Ile
3.4.15.1 0.172
-
-
 Rattus norvegicus Val-Pro
3.4.15.1 0.172
-
-
 Rattus norvegicus Val-Gly
3.4.15.1 0.199
-
-
 Rattus norvegicus Gly-Trp
3.4.15.1 0.199
-
-
 Rattus norvegicus Ala-Trp
3.4.15.1 0.224
-
-
 Rattus norvegicus Ala-Phe
3.4.15.1 0.442
-
-
 Rattus norvegicus nicotianamine