Literature summary extracted from

Suzuki, T.; Nishimukai, M.; Takechi, M.; Taguchi, H.; Hamada, S.; Yokota, A.; Ito, S.; Hara, H.; Matsui, H.
The nondigestible disaccharide epilactose increases paracellular Ca absorption via Rho-associated kinase- and myosin light chain kinase-dependent mechanisms in rat small intestines (2010), J. Agric. Food Chem., 58, 1927-1932.

Activating Compound

EC Number	Activating Compound	Comment	Organism	Structure
2.7.11.18	additional information	epilactose induces myosin light chain phosphorylation via MLCK	Rattus norvegicus

Inhibitors

EC Number	Inhibitors	Comment	Organism	Structure
2.7.11.18	ML-7	specific MLCK inhibitor	Rattus norvegicus

Organism

EC Number	Organism	UniProt	Comment	Textmining
2.7.11.18	Rattus norvegicus	-	-	-

Source Tissue

EC Number	Source Tissue	Comment	Organism	Textmining
2.7.11.18	small intestine	-	Rattus norvegicus	-

Substrates and Products (Substrate)

EC Number	Substrates	Comment Substrates	Organism	Products	Comment (Products)	Rev.	Reac.
2.7.11.18	ATP + myosin light chain	myosin light chain is phosphorylated at Thr 18 and Ser 19 by myosin light chain kinase	Rattus norvegicus	ADP + myosin light chain phosphate	-	?

Synonyms

EC Number	Synonyms	Comment	Organism
2.7.11.18	MLCK	-	Rattus norvegicus
2.7.11.18	myosin light chain kinase	-	Rattus norvegicus

Cofactor

EC Number	Cofactor	Comment	Organism	Structure
2.7.11.18	ATP	-	Rattus norvegicus

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Release 2023.1 (January 2023)