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Literature summary extracted from

  • Rai, K.; Chidester, S.; Zavala, C.V.; Manos, E.J.; James, S.R.; Karpf, A.R.; Jones, D.A.; Cairns, B.R.
    Dnmt2 functions in the cytoplasm to promote liver, brain, and retina development in zebrafish (2007), Genes Dev., 21, 261-266.
    View publication on PubMedView publication on EuropePMC

Localization

EC Number Localization Comment Organism GeneOntology No. Textmining
2.1.1.204 cytoplasm
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 Danio rerio 5737
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Organism

EC Number Organism UniProt Comment Textmining
2.1.1.204 Danio rerio
-
-
-

Source Tissue

EC Number Source Tissue Comment Organism Textmining
2.1.1.204 embryo
-
 Danio rerio
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General Information

EC Number General Information Comment Organism
2.1.1.204 malfunction knockdown of Dnmt2 protein in zebrafish embryos confers differentiation defects in particular organs, including the retina, liver, and brain Danio rerio
2.1.1.204 physiological function Dnmt2 methylates an RNA species of about 80 bases, consistent with tRNA methylation. Thus, Dnmt2 promotes zebrafish development, likely through cytoplasmic RNA methylation Danio rerio